185P Influence of corticosteroids and antibiotics on the microbiota and the efficacy of immunotherapy in patients with non-small cell lung cancer (NSCLC) by García, M. Zapata, Lastra, R., Pellitero, A. Moratiel, Ruiz, M. Gascon, Goñi, A. Sesma, Bielsa, E. Quilez, Lapena, M. Cruellas, Paño-Pardo, J.R., Del Campo, R., Ramon, M.I. Torres, Esteban, A. Yubero, Ramírez-Labrada, A., Gálvez, E.M., Pardo, J., Casado, M.D. Isla

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165P SCLC subtypes are associated with distinct dinicopathological features and outcomes: A biomarker analysis from the CANTABRICO study by Rocha, P., Sanchez, I., Pinto, L. Masfarre, Giner, M., Gorro, N. Navarro, Hoyo, A. Rios, Garcia, A. Taus, Pérez-Buira, S., Torres-Fernandez, É., Clave, S., Paricio, B. Bellosillo, Rojo, F., Paz-Ares, L., Cubells, C. Martí, de la Rosa, C. Aguado, Casado, M.D. Isla, Garcia-Campelo, R., Baez, L., Mellén, Á. Callejo, Arriola, E.

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74P Non-small cell lung cancer (NSCLC) predictors of response to immunotherapy (ICI): LIPI index and immune-related toxicity by Pellitero, A. Moratiel, Lastra, R., García, M. Zapata, Berjaga, M. Zurera, Moreno, I. Ruiz, Gómez, A. Goás, Pi, M. Martí, Monleón, A. Romero, Osorio, K., Velasco, M. Arribas, Per, S. Esteras, Ruiz, M. Gascon, Goñi, A. Sesma, Bielsa, E. Quilez, Casado, M.D. Isla

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12P Spatially preserved multi-region transcriptomic subtyping and biomarkers associated with long-term benefit with chemoimmunotherapy in extensive-stage small cell lung cancer (ES... by Peressini, M., Cubells, C. Martí, Calderon, V. Gutierrez, Sureda, B. Massuti, Majem, M., García-Campelo, M.R., Tain, P. Diz, Isla Casado, M.D., Paul, A. Moreno, Navalon, F.J. Garcia, Molero, M., Adradas, V., Gallego, E. Conde, Paz-Ares, L., Zugazagoitia, J.

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3P Exploratory efficacy analysis by smoking status in PD-L1 high patients in the phase III, non-small cell lung cancer (NSCLC) IMpower110 study by Paz-Ares, L., García-Campelo, M.R., Isla Casado, M.D., Carcereny, E., Abreu, D. Rodriguez, Gonzalez, J.J. Garcia, Parente, D. Perez, Mancha, N. Gonzalez, Vilas, E., Gracia, P. Ruiz, Greco, A., Spigel, D.R., de Marinis, F., Jassem, J.

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178P Germline testing in non-small cell lung cancer (NSCLC): Real-world impact of the discovery of germline pathogenic variants (PGV) in the INHERITY LC (ILC) study by Montes, J.C. Laguna, Lastra, R., Gomez, O. Higuera, Berjaga, M. Zurera, Pellitero, A. Moratiel, Menao-Guillen, S., Arruebo, M., Potrony, M., Sole, X., Arcocha, A., Moreno, L., Sainz, L. Gutierrez, Teixido, C., Segarra, N. Vinolas, De-Castro, J., Casado, M.D. Isla, Mezquita, L.

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120MO Adjuvant pembrolizumab versus placebo for early-stage NSCLC after resection and optional chemotherapy: Updated results from PEARLS/KEYNOTE-091 by Besse, B., Havel, L., Peters, S., Marreaud, S.I., Jha, N., Oselin, K., Esteban Gonzalez, E., Isla Casado, M.D., Martinez-Marti, A., Faehling, M., Lee, J-S., Luo, Y., Keller, S.M., Dafni, U., Mauer, M.E., Stahel, R.A., O'Brien, M.E.R., Tsuboi, M., Paz-Ares, L.

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