Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize res... by Slavish, Peter J., Cuypers, Maxime G., Rimmer, Mary Ashley, Abdolvahabi, Alireza, Jeevan, Trushar, Kumar, Gyanendra, Jarusiewicz, Jamie A., Vaithiyalingam, Sivaraja, Jones, Jeremy C., Bowling, John J., Price, Jeanine E., DuBois, Rebecca M., Min, Jaeki, Webby, Richard J., Rankovic, Zoran, White, Stephen W.

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Development of Potent and Selective Janus Kinase 2/3 Directing PG–PROTACs by Alcock, Lisa J, Chang, Yunchao, Jarusiewicz, Jamie A, Actis, Marisa, Nithianantham, Stanley, Mayasundari, Anand, Min, Jaeki, Maxwell, Dylan, Hunt, Jeremy, Smart, Brandon, Yang, Jun J, Nishiguchi, Gisele, Fischer, Marcus, Mullighan, Charles G, Rankovic, Zoran

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Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize res... by Slavish, Peter J., Cuypers, Maxime G., Rimmer, Mary Ashley, Abdolvahabi, Alireza, Jeevan, Trushar, Kumar, Gyanendra, Jarusiewicz, Jamie A., Vaithiyalingam, Sivaraja, Jones, Jeremy C., Bowling, John J., Price, Jeanine E., DuBois, Rebecca M., Min, Jaeki, Webby, Richard J., Rankovic, Zoran, White, Stephen W.

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TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA by Jonchere, Barbara, Stripay, Jennifer, Pribnow, Allison, Zindy, Frederique, Min, Jaeki, Freeman, Burgess, Shelat, Anang, Rankovic, Zoran, Roussel, Martine

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Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents by Min, Jaeki, Guo, Kexiao, Suryadevara, Praveen K, Zhu, Fangyi, Holbrook, Gloria, Chen, Yizhe, Feau, Clementine, Young, Brandon M, Lemoff, Andrew, Connelly, Michele C, Kastan, Michael B, Guy, R. Kiplin

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Lead Optimization of 3-Carboxyl-4(1H)-Quinolones to Deliver Orally Bioavailable Antimalarials by Zhang, Yiqun, Clark, Julie A, Connelly, Michele C, Zhu, Fangyi, Min, Jaeki, Guiguemde, W. Armand, Pradhan, Anupam, Iyer, Lalitha, Furimsky, Anna, Gow, Jason, Parman, Toufan, El Mazouni, Farah, Phillips, Margaret A, Kyle, Dennis E, Mirsalis, Jon, Guy, R. Kiplin

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Mechanistic Insight on the Mode of Action of Colletoic Acid by Ling, Taotao, Miller, Darcie J, Lang, Walter H, Griffith, Elizabeth, Rodriguez-Cortes, Adaris, El Ayachi, Ikbale, Palacios, Gustavo, Min, Jaeki, Miranda-Carboni, Gustavo, Lee, Richard E, Rivas, Fatima

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BRAF inhibition protects against hearing loss in mice by Ingersoll, Matthew A, Malloy, Emma A, Caster, Lauryn E, Holland, Eva M, Xu, Zhenhang, Zallocchi, Marisa, Currier, Duane, Liu, Huizhan, He, David Z Z, Min, Jaeki, Chen, Taosheng, Zuo, Jian, Teitz, Tal

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Abstract 5410: Modulating metabolic homeostasis as a therapeutic tool for leukemia by Attia, Ramy R., Min, Jaeki, Guy, Rodney K.

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Performance of a docking/molecular dynamics protocol for virtual screening of nutlin-class inhibitors of Mdmx by Bharatham, Nagakumar, Finch, Kristin E., Min, Jaeki, Mayasundari, Anand, Dyer, Michael A., Guy, R. Kiplin, Bashford, Donald

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Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins by Danelius, Emma, Pettersson, Mariell, Bred, Matilda, Min, Jaeki, Waddell, M Brett, Guy, R Kiplin, Grøtli, Morten, Erdelyi, Mate

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Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpinsElectronic supplementary information (ESI) available: Synthesis details and... by Danelius, Emma, Pettersson, Mariell, Bred, Matilda, Min, Jaeki, Waddell, M. Brett, Guy, R. Kiplin, Grøtli, Morten, Erdelyi, Mate

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A High-Throughput Screen for Compounds That Inhibit Aggregation of the Alzheimer’s Peptide by Kim, Woojin, Kim, Yunkyoung, Min, Jaeki, Kim, Dong Jin, Chang, Young-Tae, Hecht, Michael H

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Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents by Zhou, Chunhui, Min, Jaeki, Liu, Zhigang, Young, Anne, Deshazer, Heather, Gao, Tian, Chang, Young-Tae, Kallenbach, Neville R.

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Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway by Genthe, Jamie R, Min, Jaeki, Farmer, Dana M, Shelat, Anang A, Grenet, Jose A, Lin, Wenwei, Finkelstein, David, Vrijens, Karen, Chen, Taosheng, Guy, R. Kiplin, Clements, Wilson K, Roussel, Martine F

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Ca 2+ -mediated mitochondrial inner membrane permeabilization induces cell death independently of Bax and Bak by Quarato, Giovanni, Llambi, Fabien, Guy, Cliff S, Min, Jaeki, Actis, Marisa, Sun, Huan, Narina, Shilpa, Pruett-Miller, Shondra M, Peng, Junmin, Rankovic, Zoran, Green, Douglas R

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Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway by Genthe, Jamie R, Min, Jaeki, Farmer, Dana M, Shelat, Anang A, Grenet, Jose A, Lin, Wenwei, Finkelstein, David, Vrijens, Karen, Chen, Taosheng, Guy, R. Kiplin, Clements, Wilson K, Roussel, Martine F

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Abstract A28: The link between the metabolic effects of nuclear receptor (NR) modulators and anticarcinogenic properties on leukemia cancer cells can be revealed through studying t... by Attia, Ramy R., Min, Jaeki, Guy, R. Kiplin

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Hit-to-Lead Studies for the Antimalarial Tetrahydroisoquinolone Carboxanilidesi by Floyd, David M., Stein, Philip, Wang, Zheng, Liu, Jian, Castro, Steve, Clark, Julie A., Connelly, Michele, Zhu, Fangyi, Holbrook, Gloria, Matheny, Amy, Sigal, Martina S., Min, Jaeki, Dhinakaran, Rajkumar, Krishnan, Senthil, Bashyum, Sridevi, Knapp, Spencer, Guy, R. Kiplin

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Abstract LB-056: Discovery of novel small molecule inhibitors of the DCN1-Ubc12 interaction by high throughput screening technology by Min, Jaeki, Scott, Daniel C., Chai, Sergio C., Goktug, Asli N., Hammill, Jared T., Huang, Guochang, Connelly, Michele C., Matheny, Amy, Shelat, Anang, Singh, Bhuvanesh, Chen, Taosheng, Schulman, Brenda A., Guy, R. Kiplin

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