The project MinE databrowser: bringing large-scale whole-genome sequencing in ALS to researchers and the public by van der Spek, Rick A.A., van Rheenen, Wouter, Pulit, Sara L., Kenna, Kevin P., van den Berg, Leonard H., Veldink, Jan H.

Get full text

Role of Rare Genetic Variants Found in Families With Intracranial Aneurysms in the General Dutch and UK Population by Bakker, Mark K., Ettema, Roos A., Klostermann, Maxime, Rinkel, Gabriël J.E., Veldink, Jan H., Ruigrok, Ynte M.

Get full text

OTTERS: a powerful TWAS framework leveraging summary-level reference data by Dai, Qile, Zhou, Geyu, Zhao, Hongyu, Võsa, Urmo, Franke, Lude, Battle, Alexis, Teumer, Alexander, Lehtimäki, Terho, Raitakari, Olli T., Esko, Tõnu, Epstein, Michael P., Yang, Jingjing

Get full text

RNA-Sequencing Highlights Inflammation and Impaired Integrity of the Vascular Wall in Brain Arteriovenous Malformations by Hauer, Allard J., Kleinloog, Rachel, Giuliani, Fabrizio, Rinkel, Gabriël J.E., de Kort, Gerard A., Berkelbach van der Sprenkel, Jan Willem, van der Zwan, Albert, Gosselaar, Peter H., van Rijen, Peter C., de Boer-Bergsma, Jelkje J., Deelen, Patrick, Swertz, Morris A., De Muynck, Louis, Van Damme, Philip, Veldink, Jan H., Ruigrok, Ynte M., Klijn, Catharina J.M.

Get full text

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults by van Dongen, Jenny, Zilhão, Nuno R., Sugden, Karen, Heijmans, Bastiaan T., ’t Hoen, Peter A.C., van Meurs, Joyce, Isaacs, Aaron, Jansen, Rick, Franke, Lude, Boomsma, Dorret I., Pool, René, van Dongen, Jenny, Hottenga, Jouke J., van Greevenbroek, Marleen M.J., Stehouwer, Coen D.A., van der Kallen, Carla J.H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Uitterlinden, André G., van Meurs, Joyce, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha V., Hof, Peter van ’t, Deelen, Patrick, Nooren, Irene, Heijmans, Bastiaan T., Moed, Matthijs, Franke, Lude, Vermaat, Martijn, Luijk, René, Bonder, Marc Jan, van Dijk, Freerk, Arindrarto, Wibowo, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik. W., Hoen, Peter-Bram ’t, Heijmans, Bastiaan T., Hannon, Eilis J., Mill, Jonathan, Caspi, Avshalom, Agnew-Blais, Jessica, Arseneault, Louise, Corcoran, David L., Moffitt, Terrie E., Poulton, Richie, Franke, Barbara, Boomsma, Dorret I.

Get full text

RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture by Kleinloog, Rachel, Verweij, Bon H, van der Vlies, Pieter, Deelen, Patrick, Swertz, Morris A, de Muynck, Louis, Van Damme, Philip, Giuliani, Fabrizio, Regli, Luca, van der Zwan, Albert, Berkelbach van der Sprenkel, Jan W, Han, K Sen, Gosselaar, Peter, van Rijen, Peter C, Korkmaz, Emine, Post, Jan A, Rinkel, Gabriel J.E, Veldink, Jan H, Ruigrok, Ynte M

Get full text

Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population by Zanovello, Matteo, Ibáñez, Kristina, Brown, Anna-Leigh, Sivakumar, Prasanth, Bombaci, Alessandro, Santos, Liana, van Vugt, Joke J F A, Narzisi, Giuseppe, Karra, Ramita, Scholz, Sonja W, Ding, Jinhui, Gibbs, J Raphael, Chiò, Adriano, Dalgard, Clifton, Weisburd, Ben, Hanna, Michael G, Greensmith, Linda, Phatnani, Hemali, Veldink, Jan H, Traynor, Bryan J, Polke, James, Houlden, Henry, Fratta, Pietro, Tucci, Arianna

Get full text

Analysis of aneurysmal subarachnoid hemorrhage as a multistep process by Ruigrok, Ynte M., Rinkel, Gabriel J. E., Chang, Han‐Sol, Hackenberg, Katharina A. M., Etminan, Nima, Veldink, Jan H.

Get full text

Cell Specific eQTL Analysis without Sorting Cells by Westra, Harm-Jan, Arends, Danny, Esko, Tõnu, Peters, Marjolein J, Schurmann, Claudia, Schramm, Katharina, Kettunen, Johannes, Yaghootkar, Hanieh, Fairfax, Benjamin P, Andiappan, Anand Kumar, Li, Yang, Fu, Jingyuan, Karjalainen, Juha, Platteel, Mathieu, Visschedijk, Marijn, Weersma, Rinse K, Kasela, Silva, Milani, Lili, Tserel, Liina, Peterson, Pärt, Reinmaa, Eva, Hofman, Albert, Uitterlinden, André G, Rivadeneira, Fernando, Homuth, Georg, Petersmann, Astrid, Lorbeer, Roberto, Prokisch, Holger, Meitinger, Thomas, Herder, Christian, Roden, Michael, Grallert, Harald, Ripatti, Samuli, Perola, Markus, Wood, Andrew R, Melzer, David, Ferrucci, Luigi, Singleton, Andrew B, Hernandez, Dena G, Knight, Julian C, Melchiotti, Rossella, Lee, Bernett, Poidinger, Michael, Zolezzi, Francesca, Larbi, Anis, Wang, De Yun, van den Berg, Leonard H, Veldink, Jan H, Rotzschke, Olaf, Makino, Seiko, Salomaa, Veikko, Strauch, Konstantin, Völker, Uwe, van Meurs, Joyce B J, Metspalu, Andres, Wijmenga, Cisca, Jansen, Ritsert C, Franke, Lude

Get full text

Assessment of risk of ALS conferred by the GGGGCC hexanucleotide repeat expansion in C9orf72 among first-degree relatives of patients with ALS carrying the repeat expansion by Van Wijk, Iris F, Van Eijk, Ruben P A, Van Boxmeer, Loes, Westeneng, Henk-Jan, Van Es, Michael A, Van Rheenen, Wouter, Van Den Berg, Leonard H, Eijkemans, Marinus J C, Veldink, Jan H

Get full text

Drug classes affecting intracranial aneurysm risk: Genetic correlation and Mendelian randomization by Ruigrok, Ynte M, Veldink, Jan H, Bakker, Mark K

Get full text

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity by Bakker, Mark K., Kanning, Jos P., Abraham, Gad, Martinsen, Amy E., Winsvold, Bendik S., Zwart, John-Anker, Bourcier, Romain, Sawada, Tomonobu, Koido, Masaru, Kamatani, Yoichiro, Morel, Sandrine, Amouyel, Philippe, Debette, Stéphanie, Bijlenga, Philippe, Berrandou, Takiy, Ganesh, Santhi K., Bouatia-Naji, Nabila, Jones, Gregory, Bown, Matthew, Rinkel, Gabriel J.E., Veldink, Jan H., Ruigrok, Ynte M.

Get full text

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood by Tobi, Elmar W, Slieker, Roderick C, Luijk, René, Dekkers, Koen F, Stein, Aryeh D, Xu, Kate M, Slagboom, P Eline, van Zwet, Erik W, Lumey, L H, Heijmans, Bastiaan T

Get full text

Comprehensive pathway analyses of schizophrenia risk loci point to dysfunctional postsynaptic signaling by Schijven, Dick, Kofink, Daniel, Tragante, Vinicius, Verkerke, Marloes, Pulit, Sara L., Kahn, René S., Veldink, Jan H., Vinkers, Christiaan H., Boks, Marco P., Luykx, Jurjen J.

Get full text

Meta-analysis of gene expression profiling in amyotrophic lateral sclerosis: A comparison between transgenic mouse models and human patients by Saris, Christiaan G. J., Groen, Ewout J. N., Koekkoek, Johan A. F., Veldink, Jan H., Van Den Berg, Leonard H.

Get full text

Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy by Schijven, Dick, Stevelink, Remi, McCormack, Mark, van Rheenen, Wouter, Luykx, Jurjen J., Koeleman, Bobby P.C., Veldink, Jan H.

Get full text

Common Genetic Variants Contribute to Risk of Transposition of the Great Arteries by Škorić-Milosavljević, Doris, Tadros, Rafik, Bosada, Fernanda M., Tessadori, Federico, van Weerd, Jan Hendrik, Woudstra, Odilia I., Tjong, Fleur V.Y., Lahrouchi, Najim, Bajolle, Fanny, Cordell, Heather J., Agopian, A.J., Blue, Gillian M., Barge-Schaapveld, Daniela Q.C.M., Gewillig, Marc, Preuss, Christoph, Lodder, Elisabeth M., Barnett, Phil, Ilgun, Aho, Beekman, Leander, van Duijvenboden, Karel, Bokenkamp, Regina, Müller-Nurasyid, Martina, Vliegen, Hubert W., Konings, Thelma C., van Melle, Joost P., van Dijk, Arie P.J., van Kimmenade, Roland R.J., Roos-Hesselink, Jolien W., Sieswerda, Gertjan T., Meijboom, Folkert, Abdul-Khaliq, Hashim, Berger, Felix, Dittrich, Sven, Hitz, Marc-Phillip, Moosmann, Julia, Riede, Frank-Thomas, Schubert, Stephan, Galan, Pilar, Lathrop, Mark, Munter, Hans M., Al-Chalabi, Ammar, Shaw, Christopher E., Shaw, Pamela J., Morrison, Karen E., Veldink, Jan H., van den Berg, Leonard H., Evans, Sylvia, Nobrega, Marcelo A., Aneas, Ivy, Radivojkov-Blagojević, Milena, Meitinger, Thomas, Oechslin, Erwin, Mondal, Tapas, Bergin, Lynn, Smythe, John F., Altamirano-Diaz, Luis, Lougheed, Jane, Bouma, Berto J., Chaix, Marie-A., Kline, Jennie, Bassett, Anne S., Andelfinger, Gregor, van der Palen, Roel L.F., Bouvagnet, Patrice, Clur, Sally-Ann B., Breckpot, Jeroen, Kerstjens-Frederikse, Wilhelmina S., Winlaw, David S., Bauer, Ulrike M.M., Mital, Seema, Goldmuntz, Elizabeth, Keavney, Bernard, Bonnet, Damien, Mulder, Barbara J., Tanck, Michael W.T., Bakkers, Jeroen, Christoffels, Vincent M., Boogerd, Cornelis J., Postma, Alex V., Bezzina, Connie R.

Get full text

Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3′UTR protect against ALS by Eitan, Chen, Siany, Aviad, Barkan, Elad, Olender, Tsviya, van Eijk, Kristel R., Moisse, Matthieu, Farhan, Sali M. K., Danino, Yehuda M., Yanowski, Eran, Marmor-Kollet, Hagai, Rivkin, Natalia, Yacovzada, Nancy Sarah, Hung, Shu-Ting, Cooper-Knock, Johnathan, Yu, Chien-Hsiung, Louis, Cynthia, Masters, Seth L., Kenna, Kevin P., van der Spek, Rick A. A., Sproviero, William, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Jones, Ashley R., Elbaz-Alon, Yael, Cohen, Yahel, Chapnik, Elik, Rothschild, Daphna, Weissbrod, Omer, Beck, Gilad, Ainbinder, Elena, Ben-Dor, Shifra, Werneburg, Sebastian, Schafer, Dorothy P., Brown, Robert H., Shaw, Pamela J., Van Damme, Philip, van den Berg, Leonard H., Phatnani, Hemali, Segal, Eran, Ichida, Justin K., Al-Chalabi, Ammar, Veldink, Jan H., Hornstein, Eran

Get full text

Patterns of symptom development in patients with motor neuron disease by Walhout, Renée, Verstraete, Esther, van den Heuvel, Martijn P., Veldink, Jan H., van den Berg, Leonard H.

Get full text

Computing linkage disequilibrium aware genome embeddings using autoencoders by Taş, Gizem, Westerdijk, Timo, Postma, Eric, Veldink, Jan H, Schönhuth, Alexander, Balvert, Marleen

Get full text