Unconventional viral gene expression mechanisms as therapeutic targets by Ho, Jessica Sook Yuin, Zhu, Zeyu, Marazzi, Ivan

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Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation by Rialdi, Alex, Campisi, Laura, Zhao, Nan, Lagda, Arvin Cesar, Pietzsch, Colette, Ho, Jessica Sook Yuin, Martinez-Gil, Luis, Fenouil, Romain, Chen, Xiaoting, Edwards, Megan, Metreveli, Giorgi, Jordan, Stefan, Peralta, Zuleyma, Munoz-Fontela, Cesar, Bouvier, Nicole, Merad, Miriam, Jin, Jian, Weirauch, Matthew, Heinz, Sven, Benner, Chris, van Bakel, Harm, Basler, Christopher, García-Sastre, Adolfo, Bukreyev, Alexander, Marazzi, Ivan

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Discovery of a chemical probe for PRDM9 by Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud

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TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation by Ho, Jessica Sook Yuin, Mok, Bobo Wing-Yee, Campisi, Laura, Jordan, Tristan, Yildiz, Soner, Parameswaran, Sreeja, Wayman, Joseph A., Gaudreault, Natasha N., Meekins, David A., Indran, Sabarish V., Morozov, Igor, Trujillo, Jessie D., Fstkchyan, Yesai S., Rathnasinghe, Raveen, Zhu, Zeyu, Zheng, Simin, Zhao, Nan, White, Kris, Ray-Jones, Helen, Malysheva, Valeriya, Thiecke, Michiel J., Lau, Siu-Ying, Liu, Honglian, Zhang, Anna Junxia, Lee, Andrew Chak-Yiu, Liu, Wen-Chun, Jangra, Sonia, Escalera, Alba, Aydillo, Teresa, Melo, Betsaida Salom, Guccione, Ernesto, Sebra, Robert, Shum, Elaine, Bakker, Jan, Kaufman, David A., Moreira, Andre L., Carossino, Mariano, Balasuriya, Udeni B.R., Byun, Minji, Albrecht, Randy A., Schotsaert, Michael, Garcia-Sastre, Adolfo, Chanda, Sumit K., Miraldi, Emily R., Jeyasekharan, Anand D., TenOever, Benjamin R., Spivakov, Mikhail, Weirauch, Matthew T., Heinz, Sven, Chen, Honglin, Benner, Christopher, Richt, Juergen A., Marazzi, Ivan

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Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics by Zhao, Nan, Ho, Jessica Sook Yuin, Meng, Fanye, Zheng, Simin, Kurland, Andrew P., Tian, Lu, Rea-Moreno, Martha, Song, Xiangyang, Seo, Ji-Seon, Kaniskan, H. Ümit, te Velthuis, Aartjan J.W., Tortorella, Domenico, Chen, Ya-Wen, Johnson, Jeffrey R., Jin, Jian, Marazzi, Ivan

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Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection by Ho, Jessica Sook Yuin, Angel, Matthew, Ma, Yixuan, Sloan, Elizabeth, Wang, Guojun, Martinez-Romero, Carles, Alenquer, Marta, Roudko, Vladimir, Chung, Liliane, Zheng, Simin, Chang, Max, Fstkchyan, Yesai, Clohisey, Sara, Dinan, Adam M., Gibbs, James, Gifford, Robert, Shen, Rong, Gu, Quan, Irigoyen, Nerea, Campisi, Laura, Huang, Cheng, Zhao, Nan, Jones, Joshua D., van Knippenberg, Ingeborg, Zhu, Zeyu, Moshkina, Natasha, Meyer, Léa, Noel, Justine, Peralta, Zuleyma, Rezelj, Veronica, Kaake, Robyn, Rosenberg, Brad, Wang, Bo, Wei, Jiajie, Paessler, Slobodan, Wise, Helen M., Johnson, Jeffrey, Vannini, Alessandro, Amorim, Maria João, Baillie, J. Kenneth, Miraldi, Emily R., Benner, Christopher, Brierley, Ian, Digard, Paul, Łuksza, Marta, Firth, Andrew E., Krogan, Nevan, Greenbaum, Benjamin D., MacLeod, Megan K., van Bakel, Harm, Garcìa-Sastre, Adolfo, Yewdell, Jonathan W., Hutchinson, Edward, Marazzi, Ivan

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Nuclear RNA catabolism controls endogenous retroviruses, gene expression asymmetry, and dedifferentiation by Torre, Denis, Fstkchyan, Yesai S, Ho, Jessica Sook Yuin, Cheon, Youngseo, Patel, Roosheel S, Degrace, Emma J, Mzoughi, Slim, Schwarz, Megan, Mohammed, Kevin, Seo, Ji-Seon, Romero-Bueno, Raquel, Demircioglu, Deniz, Hasson, Dan, Tang, Weijing, Mahajani, Sameehan U, Campisi, Laura, Zheng, Simin, Song, Won-Suk, Wang, Ying-Chih, Shah, Hardik, Francoeur, Nancy, Soto, Juan, Salfati, Zelda, Weirauch, Matthew T, Warburton, Peter, Beaumont, Kristin, Smith, Melissa L, Mulder, Lubbertus, Villalta, S Armando, Kessenbrock, Kai, Jang, Cholsoon, Lee, Daeyoup, De Rubeis, Silvia, Cobos, Inma, Tam, Oliver, Hammell, Molly Gale, Seldin, Marcus, Shi, Yongsheng, Basu, Uttiya, Sebastiano, Vittorio, Byun, Minji, Sebra, Robert, Rosenberg, Brad R, Benner, Chris, Guccione, Ernesto, Marazzi, Ivan

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Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models by Jessica Sook Yuin Ho, Mok, Bobo Wing-Yee, Campisi, Laura, Jordan, Tristan, Yildiz, Soner, Parameswaran, Sreeja, Wayman, Joseph A, Gaudreault, Natasha N, Meekins, David A, Indran, Sabarish V, Morozov, Igor, Trujillo, Jessie D, Fstkchyan, Yesai S, Rathnasinghe, Raveen, Zhu, Zeyu, Zheng, Simin, Zhao, Nan, White, Kris, Ray-Jones, Helen, Malysheva, Valeriya, Thiecke, Michiel J, Siu-Ying Lau, Liu, Honglian, Zhang, Anna Junxia, Andrew Chak-Yiu Lee, Wen-Chun, Liu, Aydillo, Teresa, Betsaida Salom Melo, Guccione, Ernesto, Sebra, Robert, Shum, Elaine, Bakker, Jan, Kaufman, David A, Moreira, Andre L, Carossino, Mariano, Balasuriya, Udeni B R, Byun, Minji, Miraldi, Emily R, Albrecht, Randy A, Schotsaert, Michael, Garcia-Sastre, Adolfo, Chanda, Sumit K, Jeyasekharan, Anand D, Tenoever, Benjamin R, Spivakov, Mikhail, Weirauch, Matthew T, Heinz, Sven, Chen, Honglin, Benner, Christopher, Richt, Juergen A, Marazzi, Ivan

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METTL6 is a tRNA m 3 C methyltransferase that regulates pluripotency and tumor cell growth by Ignatova, Valentina V, Kaiser, Steffen, Ho, Jessica Sook Yuin, Bing, Xinyang, Stolz, Paul, Tan, Ying Xim, Lee, Chee Leng, Gay, Florence Pik Hoon, Lastres, Palma Rico, Gerlini, Raffaele, Rathkolb, Birgit, Aguilar-Pimentel, Antonio, Sanz-Moreno, Adrián, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Ibragimov, Emil, Valenta, Magdalena, Lukauskas, Saulius, Pavesi, Andrea, Marschall, Susan, Leuchtenberger, Stefanie, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabe, Bultmann, Sebastian, Rando, Oliver J, Guccione, Ernesto, Kellner, Stefanie M, Schneider, Robert

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METTL6 is a tRNA m3C methyltransferase that regulates pluripotency and tumor cell growth by Ignatova, Valentina V, Kaiser, Steffen, Ho, Jessica Sook Yuin, Bing, Xinyang, Stolz, Paul, Tan, Ying Xim, Lee, Chee Leng, Gay, Florence Pik Hoon, Lastres, Palma Rico, Gerlini, Raffaele, Rathkolb, Birgit, Aguilar-Pimentel, Antonio, Sanz-Moreno, Adrián, Klein-Rodewald, Tanja, Calzada-Wack, Julia, Ibragimov, Emil, Valenta, Magdalena, Lukauskas, Saulius, Pavesi, Andrea, Marschall, Susan, Leuchtenberger, Stefanie, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabe, Bultmann, Sebastian, Rando, Oliver J, Guccione, Ernesto, Kellner, Stefanie M, Schneider, Robert

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