Reductions in log P Improved Protein Binding and Clearance Predictions Enabling the Prospective Design of Cannabinoid Receptor (CB1) Antagonists with Desired Pharmacokinetic Proper... by Ellsworth, Bruce A, Sher, Philip M, Wu, Ximao, Wu, Gang, Sulsky, Richard B, Gu, Zhengxiang, Murugesan, Natesan, Zhu, Yeheng, Yu, Guixue, Sitkoff, Doree F, Carlson, Kenneth E, Kang, Liya, Yang, Yifan, Lee, Ning, Baska, Rose A, Keim, William J, Cullen, Mary Jane, Azzara, Anthony V, Zuvich, Eva, Thomas, Michael A, Rohrbach, Kenneth W, Devenny, James J, Godonis, Helen E, Harvey, Susan J, Murphy, Brian J, Everlof, Gerry G, Stetsko, Paul I, Gudmundsson, Olafur, Johnghar, Susan, Ranasinghe, Asoka, Behnia, Kamelia, Pelleymounter, Mary Ann, Ewing, William R

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Estimation of the Extent of in Vivo Formation of a Mutagenic Aromatic Amine from a Potent Thyromimetic Compound: Correlation of in Vitro and in Vivo Findings by Behnia, Kamelia, Cornelius, Georgia, Wang, Jian, Shipkova, Petia, Johnghar, Susan, Washburn, William, Brigance, Robert, Stetsko, Paul, Henwood, Andrew, Wojciechowski, James P, Marathe, Punit, Rodrigues, A. David, Humphreys, W. Griffith

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Characterization of a novel and selective CB1 antagonist as a radioligand for receptor occupancy studies by Yang, Yifan, Miller, Keith J., Zhu, Yeheng, Hong, Yang, Tian, Yuan, Murugesan, Natesan, Gu, Zhengxiang, O’Tanyi, Eva, Keim, William J., Rohrbach, Kenneth W., Johnghar, Susan, Behnia, Kamelia, Pelleymounter, Mary Ann, Carlson, Kenneth E., Ewing, William R.

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Discovery of pyrazine carboxamide CB1 antagonists: The introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series by Ellsworth, Bruce A., Wang, Ying, Zhu, Yeheng, Pendri, Annapurna, Gerritz, Samuel W., Sun, Chongqing, Carlson, Kenneth E., Kang, Liya, Baska, Rose A., Yang, Yifan, Huang, Qi, Burford, Neil T., Cullen, Mary Jane, Johnghar, Susan, Behnia, Kamelia, Pelleymounter, Mary Ann, Washburn, William N., Ewing, William R.

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