Alterations in Metabolome and Microbiome Associated with an Early Stress Stage in Male Wistar Rats: A Multi-Omics Approach by Hernandez-Baixauli, Julia, Puigbò, Pere, Abasolo, Nerea, Palacios-Jordan, Hector, Foguet-Romero, Elisabet, Suñol, David, Galofré, Mar, Caimari, Antoni, Baselga-Escudero, Laura, Bas, Josep M Del, Mulero, Miquel

Get full text

Detection of Early Disease Risk Factors Associated with Metabolic Syndrome: A New Era with the NMR Metabolomics Assessment by Hernandez-Baixauli, Julia, Quesada-Vázquez, Sergio, Mariné-Casadó, Roger, Gil Cardoso, Katherine, Caimari, Antoni, Del Bas, Josep M, Escoté, Xavier, Baselga-Escudero, Laura

Get full text

Constitutive HER2 Signaling Promotes Breast Cancer Metastasis through Cellular Senescence by ANGELINI, Pier Davide, ZACARIAS FLUCK, Mariano F, CANALS, Francesc, GOMIS, Roger R, TABERNERO, Josep, BASELGA, Jose, VILLANUEVA, Josep, ARRIBAS, Joaquin, PEDERSEN, Kim, LLUIS PARRA-PALAU, Josep, GUIU, Marc, BERNADO MORALES, Cristina, VICARIO, Rocio, LUQUE-GARCIA, Antonio, PEIRO NAVALPOTRO, Nerea, GIRALT, Jordi

Get full text

Dietary proanthocyanidins modulate melatonin levels in plasma and the expression pattern of clock genes in the hypothalamus of rats by Ribas‐Latre, Aleix, Del Bas, Josep M, Baselga‐Escudero, Laura, Casanova, Ester, Arola‐Arnal, Anna, Salvadó, Maria‐Josepa, Arola, Lluís, Bladé, Cinta

Get full text

Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells by Baselga-Escudero, Laura, Blade, Cinta, Ribas-Latre, Aleix, Casanova, Ester, Suárez, Manuel, Torres, Josep Lluís, Salvadó, M Josepa, Arola, Lluis, Arola-Arnal, Anna

Get full text

Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation by Anido, Judit, Scaltriti, Maurizio, Bech Serra, Joan Josep, Josefat, Belén Santiago, Rojo Todo, Federico, Baselga, José, Arribas, Joaquín

Get full text

Developing a model to predict the early risk of hypertriglyceridemia based on inhibiting lipoprotein lipase (LPL): a translational study by Hernandez-Baixauli, Julia, Chomiciute, Gertruda, Alcaide-Hidalgo, Juan María, Crescenti, Anna, Baselga-Escudero, Laura, Palacios-Jordan, Hector, Foguet-Romero, Elisabet, Pedret, Anna, Valls, Rosa M., Solà, Rosa, Mulero, Miquel, Del Bas, Josep M.

Get full text

Use of Postoperative Radiotherapy and Multiple Adjuvant Treatments After Surgical Removal of a Giant Retroauricular Keloid in a Pediatric Patient by Sicre, Joaquín Espiñeira, Ivars, Marta, Heinz, Oliver Haag, Ludwig, Peter Wienberg, Isern Verdun, Josep, Baselga Torres, Eulalia

Get full text

Gastrointestinal Adenocarcinomas of the Esophagus, Stomach, and Colon Exhibit Distinct Patterns of Genome Instability and Oncogenesis by DULAK, Austin M, SCHUMACHER, Steven E, TABERNERO, Josep, BARRETINA, Jordi, ENZINGER, Peter C, CORSO, Giovanni, ROVIELLO, Franco, LIN LIN, BANDLA, Santhoshi, LUKETICH, James D, PENNATHUR, Arjun, MEYERSON, Matthew, LIESHOUT, Jasper Van, OGINO, Shuji, SHIVDASANI, Ramesh A, BEER, David G, GODFREY, Tony E, BEROUKHIM, Rameen, BASS, Adam J, IMAMURA, Yu, FOX, Cameron, SHIM, Byoungyong, RAMOS, Alex H, SAKSENA, Gordon, BACA, Sylvan C, BASELGA, Jose

Get full text

Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors by Juric, Dejan, Dienstmann, Rodrigo, Cervantes, Andres, Hidalgo, Manuel, Messersmith, Wells, Blumenschein, Jr, George R, Tabernero, Josep, Roda, Desamparados, Calles, Antonio, Jimeno, Antonio, Wang, Xiaodong, Bohórquez, Sandra Sanabria, Leddy, Cecilia, Littman, Catherine, Kapp, Amy V, Shames, David S, Penuel, Elicia, Amler, Lukas C, Pirzkall, Andrea, Baselga, José

Get full text

Phase I Pharmacokinetic and Pharmacodynamic Study of the First-in-Class Spliceosome Inhibitor E7107 in Patients with Advanced Solid Tumors by ESKENS, Ferry A. L. M, RAMOS, Francisco J, TABERNERO, Josep, BURGER, Herman, O'BRIEN, James P, PIERA, Adelaida, DE JONGE, Maja J. A, MIZUI, Yoshiharu, WIEMER, Erik A. C, CARRERAS, Maria Josepa, BASELGA, José

Get full text

A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors by Saura, Cristina, Roda, Desamparados, Roselló, Susana, Oliveira, Mafalda, Macarulla, Teresa, Pérez-Fidalgo, José Alejandro, Morales-Barrera, Rafael, Sanchis-García, Juan Manuel, Musib, Luna, Budha, Nageshwar, Zhu, Jin, Nannini, Michelle, Chan, Wai Y, Sanabria Bohórquez, Sandra M, Meng, Raymond D, Lin, Kui, Yan, Yibing, Patel, Premal, Baselga, José, Tabernero, Josep, Cervantes, Andrés

Get full text

Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus by Di Nicolantonio, Federica, Arena, Sabrina, Tabernero, Josep, Grosso, Stefano, Molinari, Francesca, Macarulla, Teresa, Russo, Mariangela, Cancelliere, Carlotta, Zecchin, Davide, Mazzucchelli, Luca, Sasazuki, Takehiko, Shirasawa, Senji, Geuna, Massimo, Frattini, Milo, Baselga, José, Gallicchio, Margherita, Biffo, Stefano, Bardelli, Alberto

Get full text

A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-... by Reynolds, Kerry Lynn, Bedard, Philippe L, Lee, Se-Hoon, Lin, Chia-Chi, Tabernero, Josep, Alsina, Maria, Cohen, Ezra, Baselga, José, Blumenschein, Jr, George, Graham, Donna M, Garrido-Laguna, Ignacio, Juric, Dejan, Sharma, Sunil, Salgia, Ravi, Seroutou, Abdelkader, Tian, Xianbin, Fernandez, Rose, Morozov, Alex, Sheng, Qing, Ramkumar, Thiruvamoor, Zubel, Angela, Bang, Yung-Jue

Get full text

Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets by Brastianos, Priscilla K, Carter, Scott L, Santagata, Sandro, Cahill, Daniel P, Taylor-Weiner, Amaro, Jones, Robert T, Van Allen, Eliezer M, Lawrence, Michael S, Horowitz, Peleg M, Cibulskis, Kristian, Ligon, Keith L, Tabernero, Josep, Seoane, Joan, Martinez-Saez, Elena, Curry, William T, Dunn, Ian F, Paek, Sun Ha, Park, Sung-Hye, McKenna, Aaron, Chevalier, Aaron, Rosenberg, Mara, Barker, 2nd, Frederick G, Gill, Corey M, Van Hummelen, Paul, Thorner, Aaron R, Johnson, Bruce E, Hoang, Mai P, Choueiri, Toni K, Signoretti, Sabina, Sougnez, Carrie, Rabin, Michael S, Lin, Nancy U, Winer, Eric P, Stemmer-Rachamimov, Anat, Meyerson, Matthew, Garraway, Levi, Gabriel, Stacey, Lander, Eric S, Beroukhim, Rameen, Batchelor, Tracy T, Baselga, Jose, Louis, David N, Getz, Gad, Hahn, William C

Get full text

Mediterranean natural extracts improved cognitive behavior in zebrafish and healthy rats and ameliorated lps-induced cognitive impairment in a sex dependent manner by Pusceddu, Matteo M, Hernandez-Baixauli, Julia, Puiggrós, Francesc, Arola, Lluis, Caimari, Antoni, Del Bas, Josep M, Baselga, Laura

Get full text

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of SAR245409 (XL765), a Novel, Orally Administered PI3K/mTOR Inhibitor in Patients with Advanced Solid Tumors by PAPADOPOULOS, Kyriakos P, TABERNERO, Josep, MILES, Dale, LORUSSO, Patricia M, MARKMAN, Ben, PATNAIK, Amita, TOLCHER, Anthony W, BASELGA, José, WEILIANG SHI, EGILE, Coumaran, RUIZ-SOTO, Rodrigo, LAIRD, A. Douglas

Get full text

Clinical Benefit of Lapatinib-Based Therapy in Patients with Human Epidermal Growth Factor Receptor 2-Positive Breast Tumors Coexpressing the Truncated p95HER2 Receptor by SCALTRITI, Maurizio, CHANDARLAPATY, Sarat, GAGNON, Robert, KOEHLER, Maria, GOMEZ, Henry, GEYER, Charles, CAMERON, David, ARRIBAS, Joaquin, ROSEN, Neal, BASELGA, José, PRUDKIN, Ludmila, AURA, Claudia, JIMENEZ, José, ANGELINI, Pier Davide, SANCHEZ, Gertrudis, GUZMAN, Marta, PARRA, Josep Lluis, ELLIS, Catherine

Get full text

Dupilumab treatment in paediatric atopic dermatitis (2-18 years): Spanish multicentre retrospective real-world study by Iznardo, Helena, Roé, Esther, Vicente, Asunción, Prat, Carolina, Casals, Miquel, Martín-Santiago, Ana, Esteve, Altea, Viñas, Miguel, Munera-Campos, Mónica, Corella, Francesca, Mollet, Jordi, Figueras-Nart, Ignasi, Vila, Aina, Soria, Xavier, Azón-Masoliver, Antoni, Marqués-Martín, Laura, Nadal-Lladó, Cristina, Bel, Susana, Pujol-Montcusí, Josep, Bertolín-Colilla, Marta, Curto-Barredo, Laia, Melé-Ninot, Gemma, Evole, Montserrat, Berbegal, Laura, Puig, Lluís, Baselga, Eulàlia

Get full text

High HER2 expression correlates with response to the combination of lapatinib and trastuzumab by Scaltriti, Maurizio, Nuciforo, Paolo, Bradbury, Ian, Sperinde, Jeff, Agbor-Tarh, Dominique, Campbell, Christine, Chenna, Ahmed, Winslow, John, Serra, Violeta, Parra, Josep Lluis, Prudkin, Ludmila, Jimenez, José, Aura, Claudia, Harbeck, Nadia, Pusztai, Lajos, Ellis, Catherine, Eidtmann, Holger, Arribas, Joaquin, Cortes, Javier, de Azambuja, Evandro, Piccart, Martine, Baselga, José

Get full text