N -[6-Amino-2-(heteroaryl)pyrimidin-4-yl]acetamides as A 2A Receptor Antagonists with Improved Drug Like Properties and in Vivo Efficacy by Lanier, Marion C., Moorjani, Manisha, Luo, Zhiyong, Chen, Yongsheng, Lin, Emily, Tellew, John E., Zhang, Xiaohu, Williams, John P., Gross, Raymond S., Lechner, Sandra M., Markison, Stacy, Joswig, Tanya, Kargo, William, Piercey, Jaime, Santos, Mark, Malany, Siobhan, Zhao, Marilyn, Petroski, Robert, Crespo, María I., Díaz, José-Luis, Saunders, John, Wen, Jenny, O’Brien, Zhihong, Jalali, Kayvon, Madan, Ajay, Slee, Deborah H.

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Lead Optimization of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A Adenosine Receptor Antagonists for the Treatment of Parkinson’s Disease by Zhang, Xiaohu, Tellew, John E, Luo, Zhiyong, Moorjani, Manisha, Lin, Emily, Lanier, Marion C, Chen, Yongsheng, Williams, John P, Saunders, John, Lechner, Sandra M, Markison, Stacy, Joswig, Tanya, Petroski, Robert, Piercey, Jaime, Kargo, William, Malany, Siobhan, Santos, Mark, Gross, Raymond S, Wen, Jenny, Jalali, Kayvon, O’Brien, Zhihong, Stotz, Carol E, Crespo, María I, Díaz, José-Luis, Slee, Deborah H

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Identification of Novel, Water-Soluble, 2-Amino-N-pyrimidin-4-yl Acetamides as A2A Receptor Antagonists with In Vivo Efficacy by Slee, Deborah H, Zhang, Xiaohu, Moorjani, Manisha, Lin, Emily, Lanier, Marion C, Chen, Yongsheng, Rueter, Jaimie K, Lechner, Sandra M, Markison, Stacy, Malany, Siobhan, Joswig, Tanya, Santos, Mark, Gross, Raymond S, Williams, John P, Castro-Palomino, Julio C, Crespo, María I, Prat, Maria, Gual, Silvia, Díaz, José-Luis, Wen, Jenny, O’Brien, Zhihong, Saunders, John

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2-Amino-N-pyrimidin-4-ylacetamides as A2A Receptor Antagonists: 2. Reduction of hERG Activity, Observed Species Selectivity, and Structure−Activity Relationships by Slee, Deborah H, Moorjani, Manisha, Zhang, Xiaohu, Lin, Emily, Lanier, Marion C, Chen, Yongsheng, Rueter, Jaimie K, Lechner, Sandra M, Markison, Stacy, Malany, Siobhan, Joswig, Tanya, Santos, Mark, Gross, Raymond S, Williams, John P, Castro-Palomino, Julio C, Crespo, María I, Prat, Maria, Gual, Silvia, Díaz, José-Luis, Jalali, Kayvon, Sai, Yang, Zuo, Zhiyang, Yang, Chun, Wen, Jenny, O’Brien, Zhihong, Petroski, Robert, Saunders, John

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Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists by XIAOHU ZHANG, RUETER, Jaimie K, MARKISON, Stacy, JOSWIG, Tanya, MALANY, Siobhan, SANTOS, Mark, CASTRO-PALOMINO, Julio C, CRESPO, Maria I, PRAT, Maria, GUAL, Silvia, DIAZ, José-Luis, SAUNDERS, John, YONGSHENG CHEN, SLEE, Deborah H, MOORJANI, Manisha, LANIER, Marion C, LIN, Emily, GROSS, Raymond S, TELLEW, John E, WILLIAMS, John P, LECHNER, Sandra M

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N-[6-Amino-2-(heteroaryl)pyrimidin-4-yl]acetamides as A2AReceptor Antagonists with Improved Drug Like Properties and in Vivo Efficacy by LANIER, Marion C, MOORJANI, Manisha, MARKISON, Stacy, JOSWIG, Tanya, KARGO, William, PIERCEY, Jaime, SANTOS, Mark, MALANY, Siobhan, ZHAO, Marilyn, PETROSKI, Robert, CRESPO, Maria I, DIAZ, Jose-Luis, ZHIYONG LUO, SAUNDERS, John, WEN, Jenny, O'BRIEN, Zhihong, JALALI, Kayvon, MADAN, Ajay, SLEE, Deborah H, YONGSHENG CHEN, LIN, Emily, TELLEW, John E, XIAOHU ZHANG, WILLIAMS, John P, GROSS, Raymond S, LECHNER, Sandra M

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Lead Optimization of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A 2A Adenosine Receptor Antagonists for the Treatment of Parkinson’s Disease by Zhang, Xiaohu, Tellew, John E., Luo, Zhiyong, Moorjani, Manisha, Lin, Emily, Lanier, Marion C., Chen, Yongsheng, Williams, John P., Saunders, John, Lechner, Sandra M., Markison, Stacy, Joswig, Tanya, Petroski, Robert, Piercey, Jaime, Kargo, William, Malany, Siobhan, Santos, Mark, Gross, Raymond S., Wen, Jenny, Jalali, Kayvon, O’Brien, Zhihong, Stotz, Carol E., Crespo, María I., Díaz, José-Luis, Slee, Deborah H.

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N-[6-Amino-2-(heteroaryl)pyrimidin-4-yl]acetamides as A2A Receptor Antagonists with Improved Drug Like Properties and in Vivo Efficacy by Lanier, Marion C, Moorjani, Manisha, Luo, Zhiyong, Chen, Yongsheng, Lin, Emily, Tellew, John E, Zhang, Xiaohu, Williams, John P, Gross, Raymond S, Lechner, Sandra M, Markison, Stacy, Joswig, Tanya, Kargo, William, Piercey, Jaime, Santos, Mark, Malany, Siobhan, Zhao, Marilyn, Petroski, Robert, Crespo, María I, Díaz, José-Luis, Saunders, John, Wen, Jenny, O’Brien, Zhihong, Jalali, Kayvon, Madan, Ajay, Slee, Deborah H

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2-Amino- N -pyrimidin-4-ylacetamides as A 2A Receptor Antagonists: 2. Reduction of hERG Activity, Observed Species Selectivity, and Structure−Activity Relationships by Slee, Deborah H., Moorjani, Manisha, Zhang, Xiaohu, Lin, Emily, Lanier, Marion C., Chen, Yongsheng, Rueter, Jaimie K., Lechner, Sandra M., Markison, Stacy, Malany, Siobhan, Joswig, Tanya, Santos, Mark, Gross, Raymond S., Williams, John P., Castro-Palomino, Julio C., Crespo, María I., Prat, Maria, Gual, Silvia, Díaz, José-Luis, Jalali, Kayvon, Sai, Yang, Zuo, Zhiyang, Yang, Chun, Wen, Jenny, O’Brien, Zhihong, Petroski, Robert, Saunders, John

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Identification of Novel, Water-Soluble, 2-Amino- N -pyrimidin-4-yl Acetamides as A 2A Receptor Antagonists with In Vivo Efficacy by Slee, Deborah H., Zhang, Xiaohu, Moorjani, Manisha, Lin, Emily, Lanier, Marion C., Chen, Yongsheng, Rueter, Jaimie K., Lechner, Sandra M., Markison, Stacy, Malany, Siobhan, Joswig, Tanya, Santos, Mark, Gross, Raymond S., Williams, John P., Castro-Palomino, Julio C., Crespo, María I., Prat, Maria, Gual, Silvia, Díaz, José-Luis, Wen, Jenny, O’Brien, Zhihong, Saunders, John

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Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A sub(2A) receptor antagonists by Zhang, Xiaohu, Rueter, Jaimie K, Chen, Yongsheng, Moorjani, Manisha, Lanier, Marion C, Lin, Emily, Gross, Raymond S, Tellew, John E, Williams, John P, Lechner, Sandra M, Markison, Stacy, Joswig, Tanya, Malany, Siobhan, Santos, Mark, Castro-Palomino, Julio C, Crespo, Mari'a I, Prat, Maria, Gual, Silvia, Diaz, Jose-Luis, Saunders, John, Slee, Deborah H

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Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A 2A receptor antagonists by Zhang, Xiaohu, Rueter, Jaimie K., Chen, Yongsheng, Moorjani, Manisha, Lanier, Marion C., Lin, Emily, Gross, Raymond S., Tellew, John E., Williams, John P., Lechner, Sandra M., Markison, Stacy, Joswig, Tanya, Malany, Siobhan, Santos, Mark, Castro-Palomino, Julio C., Crespo, Marı´a I., Prat, Maria, Gual, Silvia, Díaz, José-Luis, Saunders, John, Slee, Deborah H.

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