Synthesis and evaluation of succinoyl-caprolactam γ-secretase inhibitors by Thompson, Lorin A., Liauw, Ann Y., Ramanjulu, Mercy M., Kasireddy-Polam, Padmaja, Mercer, Stephen E., Maduskuie, Thomas P., Glicksman, Marcie, Roach, Arthur H., Meredith, Jere E., Liu, Rui-Qin, Combs, Andrew P., Higaki, Jeffrey N., Cordell, Barbara, Seiffert, Dietmar, Zaczek, Robert C., Robertson, David W., Olson, Richard E.

Get full text

Synthesis, Structure−Activity Relationships, and in Vivo Properties of 3,4-Dihydro-1H-pyrido[2,3-b]pyrazin-2-ones as Corticotropin-Releasing Factor-1 Receptor Antagonists by Dzierba, Carolyn D, Takvorian, Amy G, Rafalski, Maria, Kasireddy-Polam, Padmaja, Wong, Harvey, Molski, Thaddeus F, Zhang, Ge, Li, Yu-Wen, Lelas, Snjezana, Peng, Yong, McElroy, John F, Zaczek, Robert C, Taub, Rebecca A, Combs, Andrew P, Gilligan, Paul J, Trainor, George L

Get full text

Synthesis and structure–activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists by Dzierba, Carolyn D., Sielecki, Thais M., Arvanitis, Argyrios G., Galka, Amy, Johnson, Tricia L., Takvorian, Amy G., Rafalski, Maria, Kasireddy-Polam, Padmaja, Vig, Shikha, Dasgupta, Bireshwar, Zhang, Ge, Molski, Thaddeus F., Wong, Harvey, Zaczek, Robert C., Lodge, Nicholas J., Combs, Andrew P., Gilligan, Paul J., Trainor, George L., Bronson, Joanne J., Macor, John E.

Get full text

Dihydropyridopyrazinones and Dihydropteridinones as Corticotropin-Releasing Factor-1 Receptor Antagonists:  Structure−Activity Relationships and Computational Modeling by Dzierba, Carolyn D, Tebben, Andrew J, Wilde, Richard G, Takvorian, Amy G, Rafalski, Maria, Kasireddy-Polam, Padmaja, Klaczkiewicz, John D, Pechulis, Anthony D, Davis, Amy L, Sweet, Mark P, Woo, Alex M, Yang, Zhicai, Ebeltoft, Sarah M, Molski, Thaddeus F, Zhang, Ge, Zaczek, Robert C, Trainor, George L, Combs, Andrew P, Gilligan, Paul J

Get full text

Synthesis, Structure−Activity Relationships, and in Vivo Properties of 3,4-Dihydro-1 H -pyrido[2,3- b ]pyrazin-2-ones as Corticotropin-Releasing Factor-1 Receptor Antagonists by Dzierba, Carolyn D., Takvorian, Amy G., Rafalski, Maria, Kasireddy-Polam, Padmaja, Wong, Harvey, Molski, Thaddeus F., Zhang, Ge, Li, Yu-Wen, Lelas, Snjezana, Peng, Yong, McElroy, John F., Zaczek, Robert C., Taub, Rebecca A., Combs, Andrew P., Gilligan, Paul J., Trainor, George L.

Get full text