Synthesis and structure based optimization of novel Akt inhibitors by Lippa, Blaise, Pan, Gonghua, Corbett, Matthew, Li, Chao, Kauffman, Goss S., Pandit, Jayvardhan, Robinson, Shaughnessy, Wei, Liuqing, Kozina, Ekaterina, Marr, Eric S., Borzillo, Gary, Knauth, Elisabeth, Barbacci-Tobin, Elsa G., Vincent, Patrick, Troutman, Merin, Baker, Deborah, Rajamohan, Francis, Kakar, Shefali, Clark, Tracey, Morris, Joel

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An Asymmetric Synthesis of (2S,5S)-5-Substituted Azepane-2-Carboxylate Derivatives by Wishka, Donn G, Bédard, Marion, Brighty, Katherine E, Buzon, Richard A, Farley, Kathleen A, Fichtner, Michael W, Kauffman, Goss S, Kooistra, Jaap, Lewis, Jason G, O’Dowd, Hardwin, Samardjiev, Ivan J, Samas, Brian, Yalamanchi, Geeta, Noe, Mark C

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An Efficient Chiral Moderator Prepared from Inexpensive (+)-3-Carene:  Synthesis of the HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor DPC 963 by Kauffman, Goss S, Harris, Gregory D, Dorow, Roberta L, Stone, Benjamin R. P, Parsons, Rodney L, Pesti, Jaan A, Magnus, Nicholas A, Fortunak, Joseph M, Confalone, Pat N, Nugent, William A

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Strategy for the Enantioselective Synthesis of trans-2,4-Disubstituted Piperidines:  Application to the CCR3 Antagonist IS811 by Kauffman, Goss S, Watson, Paul S, Nugent, William A

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The discovery of highly selective erbB2 (Her2) inhibitors for the treatment of cancer by Lippa, Blaise, Kauffman, Goss S., Arcari, Joel, Kwan, Tricia, Chen, Jinshan, Hungerford, William, Bhattacharya, Samit, Zhao, Xumiao, Williams, Courtney, Xiao, Jun, Pustilnik, Leslie, Su, Chunyan, Moyer, James D., Ma, Ling, Campbell, Mary, Steyn, Stefanus

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Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN) by Martin, Matthew W., Lancia, David R., Li, Hongbin, Schiller, Shawn E.R., Toms, Angela V., Wang, Zhongguo, Bair, Kenneth W., Castro, Jennifer, Fessler, Shawn, Gotur, Deepali, Hubbs, Stephen E., Kauffman, Goss S., Kershaw, Mark, Luke, George P., McKinnon, Crystal, Yao, Lili, Lu, Wei, Millan, David S.

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Rearrangement of Nα-Protected l-Asparagines with Iodosobenzene Diacetate. A Practical Route to β-Amino-l-alanine Derivatives by Zhang, Lin-hua, Kauffman, Goss S, Pesti, Jaan A, Yin, Jianguo

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NMR Spectroscopic Investigations of Mixed Aggregates Underlying Highly Enantioselective 1,2-Additions of Lithium Cyclopropylacetylide to Quinazolinones by Parsons, Rodney L, Fortunak, Joseph M, Dorow, Roberta L, Harris, Gregory D, Kauffman, Goss S, Nugent, William A, Winemiller, Mark D, Briggs, Timothy F, Xiang, Bosong, Collum, David B

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Synthesis of Thrombin Inhibitor DuP 714 by Wityak, John, Earl, Richard A, Abelman, Matthew M, Bethel, Yvonne B, Fisher, Barbara N, Kauffman, Goss S, Kettner, Charles A, Ma, Philip, McMillan, Janice L

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FT-1101: A Structurally Distinct Pan-BET Bromodomain Inhibitor with Activity in Preclinical Models of Hematologic Malignancies by Millan, David S, Alvarez Morales, Monica A, Barr, Kenneth J, Cardillo, Daniel, Collis, Alan, Dinsmore, Christopher J, Escobedo, Jaime A, Foley, Kevin P, Herbertz, Torsten, Hubbs, Stephen, Kauffman, Goss S, Kayser-Bricker, Katherine J, Kershaw, Mark T, Luke, George P, Martin, Matthew W, McKinnon, Crystal, Mendes, Rachel L, Muskiewicz, Kristina R, Schiller, Shawn ER, Soulard, Patricia, Talbot, Adam C, Walker, Duncan, Yao, Lili, Williams, Grace L

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Rearrangement of Nα-Protected l-Asparagine with Iodosobenzene Diacetate. A Practical Route to β-Amino-l-alanine Derivatives by Zhang, Lin-Hua, Kauffman, Goss S, Pesti, Jaan A, Yin, Jianguo

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Synthesis of the methanesulfonates of α-(4-chlorophenyl)-α-[1-(2-chlorophenyl)emenyl]-1H-1,2,4-triazole-1-ethanol and α-[1-(2-chlorophenyl)ethenyl]-α-(2,4-difluorophenyl)-1H-1,2,4-... by Pesti, Jaan A., Downard, Jill A., Lauritsen, Mark D., Kauffman, Goss S., Bryant III, Walter M., Huhn, George F., Arnett, John F., Yule, Robert E., Segretario, James, Nelson, Kimberly A., Gorko, Edward F., Page, Gary O., Lloyd, Lisa M., Olson, Richard E., Bamum, Christopher S., Mrowca, Joseph J.

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Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors by Lin, Jian, Lu, Wei, Caravella, Justin A, Campbell, Ann Marie, Diebold, R. Bruce, Ericsson, Anna, Fritzen, Edward, Gustafson, Gary R, Lancia, David R, Shelekhin, Tatiana, Wang, Zhongguo, Castro, Jennifer, Clarke, Andrea, Gotur, Deepali, Josephine, Helen R, Katz, Marie, Diep, Hien, Kershaw, Mark, Yao, Lili, Kauffman, Goss, Hubbs, Stephen E, Luke, George P, Toms, Angela V, Wang, Liann, Bair, Kenneth W, Barr, Kenneth J, Dinsmore, Christopher, Walker, Duncan, Ashwell, Susan

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