Efficient Large-Scale Synthesis of BILN 2061, a Potent HCV Protease Inhibitor, by a Convergent Approach Based on Ring-Closing Metathesis by Yee, Nathan K, Farina, Vittorio, Houpis, Ioannis N, Haddad, Nizar, Frutos, Rogelio P, Gallou, Fabrice, Wang, Xiao-jun, Wei, Xudong, Simpson, Robert D, Feng, Xuwu, Fuchs, Victor, Xu, Yibo, Tan, Jonathan, Zhang, Li, Xu, Jinghua, Smith-Keenan, Lana L, Vitous, Jana, Ridges, Michael D, Spinelli, Earl M, Johnson, Michael, Donsbach, Kai, Nicola, Thomas, Brenner, Michael, Winter, Eric, Kreye, Paul, Samstag, Wendelin

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Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors by Heim-Riether, Alexander, Taylor, Steven J., Liang, Shuang, Gao, Donghong Amy, Xiong, Zhaoming, Michael August, E., Collins, Brandon K., Farmer, Bennett T., Haverty, Kathleen, Hill-Drzewi, Melissa, Junker, Hans-Dieter, Mariana Margarit, S., Moss, Neil, Neumann, Thomas, Proudfoot, John R., Keenan, Lana Smith, Sekul, Renate, Zhang, Qiang, Li, Jun, Farrow, Neil A.

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Indole Inhibitors of MMP-13 for Arthritic Disorders by Taylor, Steven J, Abeywardane, Asitha, Liang, Shuang, Xiong, Zhaoming, Proudfoot, John R, Farmer, Bennett Sandy, Gao, Donghong A, Heim-Riether, Alexander, Smith-Keenan, Lana Louise, Muegge, Ingo, Yu, Yang, Zhang, Qiang, Souza, Donald, Panzenbeck, Mark, Goldberg, Daniel, Hill-Drzewi, Melissa, Margarit, Mariana, Collins, Brandon, Li, John Xiang, Zuvela-Jelaska, Ljiljana, Li, Jun, Farrow, Neil A

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Efficient Synthesis of (S)-2-(Cyclopentyloxycarbonyl)-amino-8-nonenoic Acid:  Key Building Block for BILN 2061, an HCV NS3 Protease Inhibitor by Wang, Xiao-jun, Zhang, Li, Smith-Keenan, Lana L, Houpis, Ioannis N, Farina, Vittorio

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N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity by Abeywardane, Asitha, Caviness, Gary, Choi, Younggi, Cogan, Derek, Gao, Amy, Goldberg, Daniel, Heim-Riether, Alexander, Jeanfavre, Debra, Klein, Elliott, Kowalski, Jennifer A., Mao, Wang, Miller, Craig, Moss, Neil, Ramsden, Philip, Raymond, Ernest, Skow, Donna, Smith-Keenan, Lana, Snow, Roger J., Wu, Frank, Wu, Jiang-Ping, Yu, Yang

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SAR studies of non-zinc-chelating MMP-13 inhibitors: Improving selectivity and metabolic stability by Gao, Donghong Amy, Xiong, Zhaoming, Heim-Riether, Alexander, Amodeo, Laura, August, E. Michael, Cao, Xianhua, Ciccarelli, Leonard, Collins, Brandon K., Harrington, Kyle, Haverty, Kathleen, Hill-Drzewi, Melissa, Li, Xiang, Liang, Shuang, Margarit, Steluta Mariana, Moss, Neil, Nagaraja, Nelamangala, Proudfoot, John, Roman, Rene, Schlyer, Sabine, Keenan, Lana Smith, Taylor, Steven, Wellenzohn, Bernd, Wiedenmayer, Dieter, Li, Jun, Farrow, Neil A.

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Practical Synthesis of 2-(2-Isopropylaminothiazol-4-yl)-7-methoxy-1H-quinolin-4-one: Key Intermediate for the Synthesis of Potent HCV NS3 Protease Inhibitor BILN 2061 by Frutos, Rogelio P., Haddad, Nizar, Houpis, Ioannis N., Johnson, Michael, Smith-Keenan, Lana L., Fuchs, Victor, Yee, Nathan K., Farina, Vittorio, Faucher, Anne-Marie, Brochu, Christian, Haché, Bruno, Duceppe, Jean-Simon, Beaulieu, Pierre

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Practical Synthesis of 2-(2-Isopropylaminothiazol-4-yl)-7-methoxy-1 H -quinolin-4-one: Key Intermediate for the Synthesis of Potent HCV NS3 Protease Inhibitor BILN 2061 by Frutos, Rogelio, Haddad, Nizar, Houpis, Ioannis, Johnson, Michael, Smith-Keenan, Lana, Fuchs, Victor, Yee, Nathan, Farina, Vittorio, Faucher, Anne-Marie, Brochu, Christian, Haché, Bruno, Duceppe, Jean-Simon, Beaulieu, Pierre

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