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Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened
by
Peukert, Stefan
,
He, Feng
,
Dai, Miao
,
Zhang, Rui
,
Sun, Yingchuan
,
Miller-Moslin, Karen
,
McEwan, Michael
,
Lagu, Bharat
,
Wang, Kate
,
Yusuff, Naeem
,
Bourret, Aaron
,
Ramamurthy, Arun
,
Maniara, Wieslawa
,
Amaral, Adam
,
Vattay, Anthony
,
Wang, Anlai
,
Guo, Ribo
,
Yuan, Jing
,
Green, John
,
Williams, Juliet
,
Buonamici, Silvia
,
Kelleher III, Joseph F.
,
Dorsch, Marion
Published in
ChemMedChem
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Cover Picture: Discovery of NVP-LEQ506, a Second-Generation Inhibitor of Smoothened (ChemMedChem 8/2013)
by
Peukert, Stefan
,
He, Feng
,
Dai, Miao
,
Zhang, Rui
,
Sun, Yingchuan
,
Miller-Moslin, Karen
,
McEwan, Michael
,
Lagu, Bharat
,
Wang, Kate
,
Yusuff, Naeem
,
Bourret, Aaron
,
Ramamurthy, Arun
,
Maniara, Wieslawa
,
Amaral, Adam
,
Vattay, Anthony
,
Wang, Anlai
,
Guo, Ribo
,
Yuan, Jing
,
Green, John
,
Williams, Juliet
,
Buonamici, Silvia
,
Kelleher III, Joseph F.
,
Dorsch, Marion
Published in
ChemMedChem
Get full text
Article
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Chemmedchem
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Subjects
Antitumor Agents
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Hedgehog Signaling
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Medicinal Chemistry
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Pyridazines
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Smoothened Inhibitors
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Animals
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Cell Line
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Chemistry, Medicinal
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Disease Models, Animal
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Dogs
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Drug Evaluation, Preclinical
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Erg1 Potassium Channel
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Ether-A-Go-Go Potassium Channels - Metabolism
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Half-Life
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Humans
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Life Sciences & Biomedicine
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Mice
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Pharmacology & Pharmacy
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Pyrazines - Chemical Synthesis
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Pyrazines - Chemistry
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Wiley-Blackwell Journals
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Wiley
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