Search Results - Ketner, Rodney J.

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  1. 1
    Development of a Control Strategy for Benzene Impurity in HPMCAS-Stabilized Spray-Dried Dispersion Drug Products Using a Science-Based and Risk-Based Approach

    Development of a Control Strategy for Benzene Impurity in HPMCAS-Stabilized Spray-Dried Dispersion Drug Products Using a Science-Based and Risk-Based Approach by Yue, Hongfei, Nicholson, Sarah J., Young, Joel D., Hsieh, Daniel, Ketner, Rodney J., Hall, Robert G., Sackett, Jeremy, Banks, Elizabeth C., Castoro, John A., Randazzo, Michael E.

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  2. 2
    Kinetics of the Reactions of Methoxybenzylidene Meldrum's Acid with Thiolate Ions, Alkoxide Ions, OH-, and Water in Aqueous DMSO. Detection and Kinetic Characterization of the SNV Intermediate

    Kinetics of the Reactions of Methoxybenzylidene Meldrum's Acid with Thiolate Ions, Alkoxide Ions, OH-, and Water in Aqueous DMSO. Detection and Kinetic Characterization of the SNV... by Bernasconi, Claude F, Ketner, Rodney J, Chen, Xin, Rappoport, Zvi

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  3. 3
    Unraveling Structure−Reactivity Relationships in SNV Reactions: Kinetics of the Reactions of Methoxybenzylidenemalononitrile, 2-(Methylthiobenzylidene)-1,3-indandione, 2-(Benzylthiobenzylidene)-1,3-indandione, and Methyl β-Methylthio-α-nitrocinnamate with OH- and Thiolate Ions in Aqueous DMSO

    Unraveling Structure−Reactivity Relationships in SNV Reactions: Kinetics of the Reactions of Methoxybenzylidenemalononitrile, 2-(Methylthiobenzylidene)-1,3-indandione, 2-(Benzylthi... by Bernasconi, Claude F, Ketner, Rodney J, Ragains, Mark L, Chen, Xin, Rappoport, Zvi

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  4. 4
    Kinetics of the Reactions of Benzylidene Meldrum's Acid with Thiolate and Alkoxide Ions in Aqueous Dimethyl Sulfoxide

    Kinetics of the Reactions of Benzylidene Meldrum's Acid with Thiolate and Alkoxide Ions in Aqueous Dimethyl Sulfoxide by Bernasconi, Claude F, Ketner, Rodney J

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  5. 5
    Acid-Catalyzed Breakdown of Alkoxide and Thiolate Ion Adducts of Benzylidene Meldrum's Acid, Methoxybenzylidene Meldrum's Acid and Thiomethoxybenzylidene Meldrum's Acid

    Acid-Catalyzed Breakdown of Alkoxide and Thiolate Ion Adducts of Benzylidene Meldrum's Acid, Methoxybenzylidene Meldrum's Acid and Thiomethoxybenzylidene Meldrum's Acid by Bernasconi, Claude F, Ketner, Rodney J, Brown, Shoshana D, Chen, Xin, Rappoport, Zvi

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  6. 6
    Kinetic Analysis of Elementary Steps in Nucleophilic Vinylic Substitution Reactions of .alpha.-Nitro-.beta.-X-stilbenes (X = OCH2CF3, OCH3, NO2) with Various Nucleophiles. Detection of the Intermediate in the Reaction of .alpha.-Nitro-.beta.-(2,2,2-trifluoroethoxy)stilbene with HOCH2CH2S- and of .beta.-Methoxy-.alpha.-nitrostilbene with CF3CH2O

    Kinetic Analysis of Elementary Steps in Nucleophilic Vinylic Substitution Reactions of .alpha.-Nitro-.beta.-X-stilbenes (X = OCH2CF3, OCH3, NO2) with Various Nucleophiles. Detectio... by Bernasconi, Claude F, Schuck, David F, Ketner, Rodney J, Weiss, Minda, Rappoport, Zvi

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  7. 7
    Reactions of substituted benzylidene Meldrum’s acids and methylthiobenzylidene Meldrum’s acids with OH–, CF3CH2O– And HOCH2CH2S– in 50% DMSO-50% water. π-Donor effects, soft acid-base interactions and transition state imbalances

    Reactions of substituted benzylidene Meldrum’s acids and methylthiobenzylidene Meldrum’s acids with OH–, CF3CH2O– And HOCH2CH2S– in 50% DMSO-50% water. π-Donor effects, soft acid-b... by Bernasconi, Claude F., Ketner, Rodney J., Chen, Xin, Rappoport, Zvi

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  8. 8
    Large Steric Effect in the Substitution Reaction of Amines with Phosphoimidazolide-Activated Nucleosides

    Large Steric Effect in the Substitution Reaction of Amines with Phosphoimidazolide-Activated Nucleosides by Kanavarioti, Anastassia, Stronach, Michael W, Ketner, Rodney J, Hurley, T. Brian

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  9. 9
    The CF3CH2O- Adducts of .alpha.-Nitro-.beta.-(2,2,2-trifluoroethoxy)stilbene and .beta.-Methoxy-.alpha.-nitrostilbene, and the MeO- Adducts of .beta.-Methoxy-.alpha.-nitrostilbene. Kinetics of Competition between Protonation and Acid Catalyzed Alkoxide Ion Departure

    The CF3CH2O- Adducts of .alpha.-Nitro-.beta.-(2,2,2-trifluoroethoxy)stilbene and .beta.-Methoxy-.alpha.-nitrostilbene, and the MeO- Adducts of .beta.-Methoxy-.alpha.-nitrostilbene.... by Bernasconi, Claude F, Schuck, David F, Ketner, Rodney J, Eventova, Irina, Rappoport, Zvi

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  10. 10
    Unraveling Structure−Reactivity Relationships in S N V Reactions: Kinetics of the Reactions of Methoxybenzylidenemalononitrile, 2-(Methylthiobenzylidene)-1,3-indandione, 2-(Benzylthiobenzylidene)-1,3-indandione, and Methyl β-Methylthio-α-nitrocinnamate with OH - and Thiolate Ions in Aqueous DMSO

    Unraveling Structure−Reactivity Relationships in S N V Reactions: Kinetics of the Reactions of Methoxybenzylidenemalononitrile, 2-(Methylthiobenzylidene)-1,3-indandione, 2-(Benzylt... by Bernasconi, Claude F., Ketner, Rodney J., Ragains, Mark L., Chen, Xin, Rappoport, Zvi

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  11. 11
    Kinetics of the Reactions of Methoxybenzylidene Meldrum's Acid with Thiolate Ions, Alkoxide Ions, OH - , and Water in Aqueous DMSO. Detection and Kinetic Characterization of the S N V Intermediate

    Kinetics of the Reactions of Methoxybenzylidene Meldrum's Acid with Thiolate Ions, Alkoxide Ions, OH - , and Water in Aqueous DMSO. Detection and Kinetic Characterization of the S... by Bernasconi, Claude F., Ketner, Rodney J., Chen, Xin, Rappoport, Zvi

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