Early trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study by Lallemand, Perrine, Looney, David, Mock, Rebecca, Chung, Lucy, Adam, Stacey J., Collins, Gary, Denning, Eileen, Vock, David, Burris, Sarah, Baker, Rebecca, Duque, Krizia, Mosaly, Nilima, Mourad, Ahmaad, Giangiacomo, Dana M., Sturek, Jeffrey M., Green, China J., Towfighi, Amytis, Leong, Janet, Lee, Myounghee, Oldmixon, Cathryn, Fitzgerald, Laura, Talmor, Daniel, Agrawal, Anika, Yee, Kimberley J., Hughes, Alyssa R., Agarwal, Trisha, Park, Pauline K., McSparron, Jake I., Nkemdirim, William, Mehkri, Omar, Hindoyan, Niree A., Wallick, Julie A., Dhar, Sanjay, de Wit, Marjolein, Bledsoe, Joseph, Duckworth, Sarah, Sittler, Daniel, Felix, Lewis Oscar, Wylie, Jamie-Crystal, Heysu, Rubio-Gomez, Kambo, Amy, Jazrawi, Jehan, Melvin, Casey, Wyles, David, Kim, Mina, Hatlen, Timothy, Temblador, Cindi, Guerrero, Mario, Martin, Dannae, Drekonja, Dimitri, Hamel, Aimee, Leuck, Anne-Marie, Koker, Brittany, Dillon, Laura, Ochalek, Tracy, Nguyen, Lam, Tanner, Nichole T., Lee, Robert H., Thorlacius-Ussing, Louise, Tinggaard, Michaela, Arp, Bodil C., Knudtzen, Fredrikke C., Andreassen, Helle Frost, Pedersen, Lars, Wiese, Lothar, Ausin, Cristina, Nuñez-Orantos, M.J., López-Montesinos, Inmaculada, Carratalà, Jordi, West, Emily, Goes pharmacist, Josefine, Bednarska, Agnieszka, Bienkowski, Carlo, Yeo, Tsin Wen, Baeck, Ines M., Touloumi, Giota, Protopapas, K., Gianniou, N., Arfara-Melanini, M., Kimuli, Ivan, Nsereko, Christoher, Fred, Aniongo, Alaba, Jeniffer, Ogavu, Joseph, Pereira, Kássia, Osei, Suzette, Lin, Leo, Ma, Ji, Becker, Nancy, Asomah, Mabel, Tang, Olivia, Eccard-Koons, Vanessa, Cash, Jennifer, Linton, Jessica, Osborne, C.K., Bielica, Mona, Huber, Lynda, Krauss, Gary, Imamichi, Tom, Paudel, Sharada

Get full text

Development of a Fluorescence-based Trypanosoma cruzi CYP51 Inhibition Assay for Effective Compound Triaging in Drug Discovery Programmes for Chagas Disease: e0004014 by Riley, Jennifer, Brand, Stephen, Voice, Michael, Caballero, Ivan, Calvo, David, Read, Kevin D

Get full text

Effectiveness of treatment for class II malocclusion with the herbst or twin-block appliances: a randomized, controlled trial by O’Brien, Kevin, Wright, Jean, Conboy, Frances, Sanjie, YeWeng, Mandall, Nicky, Chadwick, Stephen, Connolly, Ivan, Cook, Paul, Birnie, David, Hammond, Mark, Harradine, Nigel, Lewis, David, McDade, Cathy, Mitchell, Laura, Murray, Alison, O’Neill, Julian, Read, Mike, Robinson, Stephen, Roberts-Harry, Dai, Sandler, Jonathan, Shaw, Ian

Get full text

Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma bruceiN-Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Tre... by Brand, Stephen, Norcross, Neil R, Thompson, Stephen, Harrison, Justin R, Smith, Victoria C, Robinson, David A, Torrie, Leah S, McElroy, Stuart P, Hallyburton, Irene, Norval, Suzanne, Scullion, Paul, Stojanovski, Laste, Simeons, Frederick RC, van Aalten, Daan, Frearson, Julie A, Brenk, Ruth, Fairlamb, Alan H, Ferguson, Michael AJ, Wyatt, Paul G, Gilbert, Ian H, Read, Kevin D

Get full text

Cover Picture: Development of Small-Molecule Trypanosoma brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode (ChemMedChem 11/2015) by Spinks, Daniel, Smith, Victoria, Thompson, Stephen, Robinson, David A., Luksch, Torsten, Smith, Alasdair, Torrie, Leah S., McElroy, Stuart, Stojanovski, Laste, Norval, Suzanne, Collie, Iain T., Hallyburton, Irene, Rao, Bhavya, Brand, Stephen, Brenk, Ruth, Frearson, Julie A., Read, Kevin D., Wyatt, Paul G., Gilbert, Ian H.

Get full text

RESPECT-ED: Rates of Pulmonary Emboli by Mountain, David, Keijzers, Gerben, Chu, Kevin, Joseph, Anthony, Read, Catherine, Blecher, Gabriel, Furyk, Jeremy, Bharat, Chrianna, Velusamy, Karthik, Munro, Andrew, Baker, Kylie, Kinnear, Frances, Mukherjee, Ahses, Watkins, Gina, Buntine, Paul, Livesay, Georgia, Fatovich, Daniel

Get full text

Cyclin-dependent kinase 12, a novel drug target for visceral leishmaniasis by Wyllie, Susan, Thomas, Michael, Patterson, Stephen, Crouch, Sabrinia, De Rycker, Manu, Lowe, Rhiannon, Gresham, Stephanie, Urbaniak, Michael D., Otto, Thomas D., Stojanovski, Laste, Simeons, Frederick, Manthri, Sujatha, MacLean, Lorna M., Zuccotto, Fabio, Homeyer, Nadine, Pflaumer, Hannah, Boesche, Markus, Sastry, Lalitha, Connolly, Paul, Albrecht, Sebastian, Berriman, Matt, Drewes, Gerard, Gray, David W., Ghidelli-Disse, Sonja, Dixon, Susan, Fiandor, Jose M., Wyatt, Paul G., Ferguson, Michael A. J., Fairlamb, Alan H., Miles, Timothy J., Read, Kevin D., Gilbert, Ian H.

Get full text

Protocol of the Australasian Malignant Pleural Effusion (AMPLE) trial: a multicentre randomised study comparing indwelling pleural catheter versus talc pleurodesis by Fysh, Edward T H, Thomas, Rajesh, Read, Catherine A, Lam, Ben C H, Yap, Elaine, Horwood, Fiona C, Lee, Pyng, Piccolo, Francesco, Shrestha, Ranjan, Garske, Luke A, Lam, David C L, Rosenstengel, Andrew, Bint, Michael, Murray, Kevin, Smith, Nicola A, Lee, Y C Gary

Get full text

Prevention of MKK6-Dependent Activation by Binding to p38α MAP Kinase by Sullivan, Jane E, Holdgate, Geoffrey A, Campbell, Douglas, Timms, David, Gerhardt, Stefan, Breed, Jason, Breeze, Alexander L, Bermingham, Alun, Pauptit, Richard A, Norman, Richard A, Embrey, Kevin J, Read, Jon, VanScyoc, Wendy S, Ward, Walter H. J

Get full text

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis by Baragaña, Beatriz, Hallyburton, Irene, Lee, Marcus C S, Norcross, Neil R, Grimaldi, Raffaella, Otto, Thomas D, Proto, William R, Blagborough, Andrew M, Meister, Stephan, Wirjanata, Grennady, Ruecker, Andrea, Upton, Leanna M, Abraham, Tara S, Almeida, Mariana J, Pradhan, Anupam, Porzelle, Achim, Martínez, María Santos, Bolscher, Judith M, Woodland, Andrew, Luksch, Torsten, Norval, Suzanne, Zuccotto, Fabio, Thomas, John, Simeons, Frederick, Stojanovski, Laste, Osuna-Cabello, Maria, Brock, Paddy M, Churcher, Tom S, Sala, Katarzyna A, Zakutansky, Sara E, Jiménez-Díaz, María Belén, Sanz, Laura Maria, Riley, Jennifer, Basak, Rajshekhar, Campbell, Michael, Avery, Vicky M, Sauerwein, Robert W, Dechering, Koen J, Noviyanti, Rintis, Campo, Brice, Frearson, Julie A, Angulo-Barturen, Iñigo, Ferrer-Bazaga, Santiago, Gamo, Francisco Javier, Wyatt, Paul G, Leroy, Didier, Siegl, Peter, Delves, Michael J, Kyle, Dennis E, Wittlin, Sergio, Marfurt, Jutta, Price, Ric N, Sinden, Robert E, Winzeler, Elizabeth A, Charman, Susan A, Bebrevska, Lidiya, Gray, David W, Campbell, Simon, Fairlamb, Alan H, Willis, Paul A, Rayner, Julian C, Fidock, David A, Read, Kevin D, Gilbert, Ian H

Get full text

Cohort Profile: The Canadian Observational Cohort collaboration by PALMER, Alexis K, KLEIN, Marina B, TSOUKAS, Christos, YIP, Benita, MILAN, David, HOGG, Robert S, RABOUD, Janet, COOPER, Curtis, HOSEIN, Sean, LOUTFY, Mona, MACHOUF, Nima, MONTANER, Julio, ROURKE, Sean B, SMIEJA, Marek

Get full text

Does HPV type affect outcome in oropharyngeal cancer? by Nichols, Anthony C, Dhaliwal, Sandeep S, Palma, David A, Basmaji, John, Chapeskie, Corina, Dowthwaite, Samuel, Franklin, Jason H, Fung, Kevin, Kwan, Keith, Wehrli, Brett, Howlett, Chris, Siddiqui, Iram, Salvadori, Marina I, Winquist, Eric, Ernst, Scott, Kuruvilla, Sara, Read, Nancy, Venkatesan, Varagur, Todorovic, Biljana, Hammond, J Alex, Koropatnick, James, Mymryk, Joe S, Yoo, John, Barrett, John W

Get full text

Abstract C59: Role of MTH1 (NUTD1) in cancer cell survival by Alwan, Husam, Eckersley, Kay, Goodwin, Louise, Lau, Alan, Jones, David, Kettle, Jason, Nissink, Willem M., Read, Jon, Scott, James S., Taylor, Benjamin J.M., Walker, Graeme E., Foote, Kevin M.

Get full text

Drinking Water From Private Wells and Risks to Children by Rogan, Walter J, Brady, Michael T, Committee on Environmental Health, and Committee on Infectious Diseases

Get full text

The Luminosity and Mass Functions of Low-Mass Stars in the Galactic Disk. I. The Calibration Region by Covey, Kevin R, Hawley, Suzanne L, Bochanski, John J, West, Andrew A, Reid, I. Neill, Golimowski, David A, Davenport, James R. A, Henry, Todd, Uomoto, Alan, Holtzman, Jon A

Get full text

Factors associated with virological suppression among HIV‐positive individuals on highly active antiretroviral therapy in a multi‐site Canadian cohort by Cescon, AM, Cooper, C, Chan, K, Palmer, AK, Klein, MB, Machouf, N, Loutfy, MR, Raboud, J, Rachlis, A, Ding, E, Lima, VD, Montaner, JSG, Rourke, SB, Smieja, M, Tsoukas, C, Hogg, RS

Get full text

Predictors of unstructured antiretroviral treatment interruption and resumption among HIV‐positive individuals in Canada by Samji, H, Taha, TE, Moore, D, Burchell, AN, Cescon, A, Cooper, C, Raboud, JM, Klein, MB, Loutfy, MR, Machouf, N, Tsoukas, CM, Montaner, JSG, Hogg, RS, Aykroyd, G, Balfour, L, Bayoumi, A, Burchell, A, Cairney, J, Calzavara, L, Cescon, A, Cooper, C, Gough, K, Guillemi, S, Harrigan, PR, Harris, M, Hatzakis, G, Hogg, R, Hosein, S, Kilby, D, Klein, M, Lalonde, R, Lima, V, Loutfy, M, Machouf, N, Mills, E, Millson, P, Montaner, J, Moore, D, Palmer, A, Raboud, J, Rachlis, A, Read, S, Rourke, S, Samji, H, Smieja, M, Salit, I, Taylor, D, Trottier, B, Tsoukas, C, Walmsley, S, Wobeser, W, Fisher, M, Gardner, S, Gataric, N, Colley, G, Rueda, S, Yip, B

Get full text

Lack of Consensus in the Diagnosis and Treatment for Ocular Tuberculosis among Uveitis Specialists by Lou, Susan M., Larkin, Kelly L., Winthrop, Kevin, Rosenbaum, James T.

Get full text

Effectiveness of early orthodontic treatment with the twin-block appliance: a multicenter, randomized, controlled trial. Part 2: psychosocial effects by O'Brien, Kevin, Wright, Jean, Conboy, Frances, Chadwick, Stephen, Connolly, Ivan, Cook, Paul, Birnie, David, Hammond, Mark, Harradine, Nigel, Lewis, David, McDade, Cathy, Mitchell, Laura, Murray, Alison, O'Neill, Julian, Read, Mike, Robinson, Stephen, Roberts-Harry, Dai, Sandler, Jonathan, Shaw, Ian, Berk, Nancy W

Get full text

Intellectual enrichment and genetic modifiers of cognition and brain volume in Huntington's disease by Papoutsi, Marina, Flower, Michael, Hensman Moss, Davina J, Holmans, Peter, Estevez-Fraga, Carlos, Johnson, Eileanoir B, Scahill, Rachael I, Rees, Geraint, Langbehn, Douglas, Tabrizi, Sarah J

Get full text