Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity by Mabanglo, Mark F., Wilson, Brian, Noureldin, Mahmoud, Kimani, Serah W., Mamai, Ahmed, Krausser, Chiara, González-Álvarez, Héctor, Srivastava, Smriti, Mohammed, Mohammed, Hoffer, Laurent, Chan, Manuel, Avrumutsoae, Jamie, Li, Alice Shi Ming, Hajian, Taraneh, Tucker, Sarah, Green, Stuart, Szewczyk, Magdalena, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Ackloo, Suzanne, Loppnau, Peter, Li, Yanjun, Seitova, Almagul, Kiyota, Taira, Wang, Jue George, Privé, Gilbert G., Kuntz, Douglas A., Patel, Bhashant, Rathod, Vaibhavi, Vala, Anand, Rout, Bhimsen, Aman, Ahmed, Poda, Gennady, Uehling, David, Ramnauth, Jailall, Halabelian, Levon, Marcellus, Richard, Al-awar, Rima, Vedadi, Masoud

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The co-crystal structure of Cbl-b and a small-molecule inhibitor reveals the mechanism of Cbl-b inhibition by Kimani, Serah W., Perveen, Sumera, Szewezyk, Magdalena, Zeng, Hong, Dong, Aiping, Li, Fengling, Ghiabi, Pegah, Li, Yanjun, Chau, Irene, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Vedadi, Masoud, Halabelian, Levon

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A ligand discovery toolbox for the WWE domain family of human E3 ligases by Münzker, Lena, Kimani, Serah W., Fowkes, Milan M., Dong, Aiping, Zheng, Hong, Li, Yanjun, Dasovich, Morgan, Zak, Krzysztof M., Leung, Anthony K. L., Elkins, Jonathan M., Kessler, Dirk, Arrowsmith, Cheryl H., Halabelian, Levon, Böttcher, Jark

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Discovery of a Novel DCAF1 Ligand Using a Drug–Target Interaction Prediction Model: Generalizing Machine Learning to New Drug Targets by Kimani, Serah W., Owen, Julie, Green, Stuart R., Li, Fengling, Li, Yanjun, Dong, Aiping, Brown, Peter J., Ackloo, Suzanne, Kuter, David, Yang, Cindy, MacAskill, Miranda, MacKinnon, Stephen Scott, Arrowsmith, Cheryl H., Schapira, Matthieu, Shahani, Vijay, Halabelian, Levon

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A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins by Ackloo, Suzanne, Li, Fengling, Szewczyk, Magda, Seitova, Almagul, Loppnau, Peter, Zeng, Hong, Xu, Jin, Ahmad, Shabbir, Arnautova, Yelena A, Baghaie, A J, Beldar, Serap, Bolotokova, Albina, Centrella, Paolo A, Chau, Irene, Clark, Matthew A, Cuozzo, John W, Dehghani-Tafti, Saba, Disch, Jeremy S, Dong, Aiping, Dumas, Antoine, Feng, Jianwen A, Ghiabi, Pegah, Gibson, Elisa, Gilmer, Justin, Goldman, Brian, Green, Stuart R, Guié, Marie-Aude, Guilinger, John P, Harms, Nathan, Herasymenko, Oleksandra, Houliston, Scott, Hutchinson, Ashley, Kearnes, Steven, Keefe, Anthony D, Kimani, Serah W, Kramer, Trevor, Kutera, Maria, Kwak, Haejin A, Lento, Cristina, Li, Yanjun, Liu, Jenny, Loup, Joachim, Machado, Raquel A C, Mulhern, Christopher J, Perveen, Sumera, Righetto, Germanna L, Riley, Patrick, Shrestha, Suman, Sigel, Eric A, Silva, Madhushika, Sintchak, Michael D, Slakman, Belinda L, Taylor, Rhys D, Thompson, James, Torng, Wen, Underkoffler, Carl, von Rechenberg, Moritz, Walsh, Ryan T, Watson, Ian, Wilson, Derek J, Wolf, Esther, Yadav, Manisha, Yazdi, Aliakbar K, Zhang, Junyi, Zhang, Ying, Santhakumar, Vijayaratnam, Edwards, Aled M, Barsyte-Lovejoy, Dalia, Schapira, Matthieu, Brown, Peter J, Halabelian, Levon, Arrowsmith, Cheryl H

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The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning by Weber, Brandon W, Kimani, Serah W, Varsani, Arvind, Cowan, Donald A, Hunter, Roger, Venter, Gerhard A, Gumbart, James C, Sewell, B Trevor

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Structure of an aliphatic amidase from Geobacillus pallidus RAPc8 by Kimani, Serah W., Agarkar, Vinod B., Cowan, Donald A., Sayed, Muhammed F.-R., Sewell, B. Trevor

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The quaternary structure of the amidase from Geobacillus pallidus RAPc8 is revealed by its crystal packing by Agarkar, Vinod B., Kimani, Serah W., Cowan, Donald A., Sayed, Muhammed F.-R., Sewell, B. Trevor

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The Mechanism of the Amidases by Weber, Brandon W., Kimani, Serah W., Varsani, Arvind, Cowan, Donald A., Hunter, Roger, Venter, Gerhard A., Gumbart, James C., Sewell, B. Trevor

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Discovery of Nanomolar DCAF1 Small Molecule Ligands by Li, Alice Shi Ming, Kimani, Serah, Wilson, Brian, Noureldin, Mahmoud, González-Álvarez, Héctor, Mamai, Ahmed, Hoffer, Laurent, Guilinger, John P., Zhang, Ying, von Rechenberg, Moritz, Disch, Jeremy S., Mulhern, Christopher J., Slakman, Belinda L., Cuozzo, John W., Dong, Aiping, Poda, Gennady, Mohammed, Mohammed, Saraon, Punit, Mittal, Manish, Modh, Pratik, Rathod, Vaibhavi, Patel, Bhashant, Ackloo, Suzanne, Santhakumar, Vijayaratnam, Szewczyk, Magdalena M, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Marcellus, Richard, Guié, Marie-Aude, Keefe, Anthony D., Brown, Peter J., Halabelian, Levon, Al-awar, Rima, Vedadi, Masoud

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Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa by Ochong, Edwin, Nzila, Alexis, Kimani, Serah, Kokwaro, Gilbert, Mutabingwa, Theonest, Watkins, William, Marsh, Kevin

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