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Circulating acetaminophen metabolites are toxicokinetic biomarkers of acute liver injury
by
Vliegenthart, ADB
,
Kimmitt, RA
,
Seymour, JH
,
Homer, NZ
,
Clarke, JI
,
Eddleston, M
,
Gray, A
,
Wood, DM
,
Dargan, PI
,
Cooper, JG
,
Antoine, DJ
,
Webb, DJ
,
Lewis, SC
,
Bateman, DN
,
Dear, JW
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Clinical pharmacology and therapeutics
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Clinical Pharmacology & Therapeutics
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Clinical Pharmacology And Therapeutics
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Acetaminophen - Blood
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Acetaminophen - Toxicity
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Acetylcysteine - Pharmacology
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Adult
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Alanine Transaminase - Metabolism
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Analgesics, Non-Narcotic - Blood
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Analgesics, Non-Narcotic - Toxicity
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Antiemetics - Adverse Effects
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Area Under Curve
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Biomarkers - Blood
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Chemical And Drug Induced Liver Injury - Blood
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Cohort Studies
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Cytochrome P-450 Enzyme System - Metabolism
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Drug Interactions
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Drug Overdose - Metabolism
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Drug Overdose - Therapy
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Female
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Free Radical Scavengers - Pharmacology
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Humans
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Life Sciences & Biomedicine
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