First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies by Munster, Pamela, Aggarwal, Rahul, Hong, David, Schellens, Jan H M, van der Noll, Ruud, Specht, Jennifer, Witteveen, Petronella O, Werner, Theresa L, Dees, E Claire, Bergsland, Emily, Agarwal, Neeraj, Kleha, Joseph F, Durante, Michael, Adams, Laurel, Smith, Deborah A, Lampkin, Thomas A, Morris, Shannon R, Kurzrock, Razelle

Get full text

Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors by Tolcher, Anthony W., Kurzrock, Razelle, Valero, Vincente, Gonzalez, Rene, Heist, Rebecca S., Tan, Antoinette R., Means-Powell, Julie, Werner, Theresa L., Becerra, Carlos, Wang, Chenxi, Leonowens, Cathrine, Kalyana-Sundaram, Shanker, Kleha, Joseph F., Gauvin, Jennifer, D’Amelio, Anthony M., Ellis, Catherine, Ibrahim, Nageatte, Yan, Li

Get full text

Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitors boceprevir and telaprev... by Wire, Mary Beth, Fang, Lei, Hussaini, Azra, Kleha, Joseph F, Theodore, Dickens

Get full text

Erratum for Wire et al., Lack of clinically significant pharmacokinetic interaction between the thrombopoietin receptor agonist eltrombopag and hepatitis C virus protease inhibitor... by Wire, Mary Beth, Fang, Lei, Hussaini, Azra, Kleha, Joseph F, Theodore, Dickens

Get full text

POLARIS: A phase 2 trial of encorafenib plus binimetinib evaluating high-dose and standard-dose regimens in patients with BRAF V600-mutant melanoma with brain metastasis by Menzies, Alexander M, Long, Georgina V, Kohn, Amiee, Tawbi, Hussein, Weber, Jeffrey, Flaherty, Keith, McArthur, Grant A, Ascierto, Paolo A, Pfluger, Yanina, Lewis, Karl, Tsai, Katy K, Hamid, Omid, Prenen, Hans, Fein, Luis, Wang, Erjian, Guenzel, Carolin, Zhang, Fan, Kleha, Joseph F, di Pietro, Alessandra, Davies, Michael A

Get full text

A randomized, double-blind, placebo-controlled study to evaluate the effect of repeated oral doses of pazopanib on cardiac conduction in patients with solid tumors by Heath, Elisabeth I., Infante, Jeffrey, Lewis, Lionel D., Luu, Thehang, Stephenson, Joe, Tan, Antoinette R., Kasubhai, Saifuddin, LoRusso, Patricia, Ma, Bo, Suttle, A. Benjamin, Kleha, Joseph F., Ball, Howard A., Dar, Mohammed M.

Get full text

A Comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors by Naing, Aung, Kurzrock, Razelle, Adams, Laurel M., Kleha, Joseph F., Laubscher, Kevin H., Bonate, Peter L., Weller, Steven, Fitzgerald, Colleen, Xu, Yanmei, LoRusso, Patricia M.

Get full text

Efficacy and safety of fluticasone propionate hydrofluoroalkane inhalation aerosol in pre–school-age children with asthma: A randomized, double-blind, placebo-controlled study by Qaqundah, Paul Y., Sugerman, Robert W., Ceruti, Elaina, Maspero, Jorge Fernando, Kleha, Joseph F., Scott, Catherine A., Wu, Wei, Mehta, Rashmi, Crim, Courtney

Get full text

Constitutive endothelin-1 overexpression promotes smooth muscle cell proliferation via an external autocrine loop by ALBERTS, G. F, PEIFLEY, K. A, JOHNS, A, KLEHA, J. F, WINKLES, J. A

Get full text

EDRF release from canine coronary artery by lectins by Kleha, Joseph F., Devesly, Pierre, Johns, Anthony

Get full text

The effects of lectins on the release of EDRF from rabbit aorta by Kleha, Joseph F., Devesly, Pierre, Johns, Anthony

Get full text