Synthesis and SAR of sulfoxide substituted carboxyquinolines as NK3 receptor antagonists by Xiong, Hui, Kang, James, Woods, James M., McCauley, John P., Koether, Gerard M., Albert, Jeffrey S., Hinkley, Lindsay, Li, Yan, Gadient, Reto A., Simpson, Thomas R.

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4-Aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators by Xiong, Hui, Brugel, Todd A., Balestra, Michael, Brown, Dean G., Brush, Kelly A., Hightower, Caprice, Hinkley, Lindsay, Hoesch, Valerie, Kang, James, Koether, Gerard M., McCauley, John P., McLaren, Francis M., Panko, Laura M., Simpson, Thomas R., Smith, Reed W., Woods, James M., Brockel, Becky, Chhajlani, Vijay, Gadient, Reto A., Spear, Nathan, Sygowski, Linda A., Zhang, Minli, Arora, Jalaj, Breysse, Nathalie, Wilson, Julie M., Isaac, Methvin, Slassi, Abdelmalik, King, Megan M.

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SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2 by Brugel, Todd A., Smith, Reed W., Balestra, Michael, Becker, Christopher, Daniels, Thalia, Koether, Gerard M., Throner, Scott R., Panko, Laura M., Brown, Dean G., Liu, Ruifeng, Gordon, John, Peters, Matthew F.

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Discovery of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as selective antagonists of the kappa opioid receptor. Part 1 by Brugel, Todd A., Smith, Reed W., Balestra, Michael, Becker, Christopher, Daniels, Thalia, Hoerter, Tiffany N., Koether, Gerard M., Throner, Scott R., Panko, Laura M., Folmer, James J., Cacciola, Joseph, Hunter, Angela M., Liu, Ruifeng, Edwards, Philip D., Brown, Dean G., Gordon, John, Ledonne, Norman C., Pietras, Mark, Schroeder, Patricia, Sygowski, Linda A., Hirata, Lee T., Zacco, Anna, Peters, Matthew F.

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Design, Synthesis, and SAR of Tachykinin Antagonists:  Modulation of Balance in NK1/NK2 Receptor Antagonist Activity by Albert, Jeffrey S, Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R, Bialecki, Russell A, Dedinas, Robert, Dembofsky, Bruce T, Hill, Daniel, Kirkland, Karin, Koether, Gerard M, Kosmider, Benedict J, Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J, Russell, Keith

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Design and optimization of cyclized NK1 antagonists with controlled atropisomeric properties by Albert, Jeffrey S, Ohnmacht, Cyrus, Bernstein, Peter R, Rumsey, William L, Aharony, David, Masek, Brian B, Dembofsky, Bruce T, Koether, Gerard M, Potts, William, Evenden, John L

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Naphtho[2,1-b][1,5] and [1,2-f][1,4]oxazocines as selective NK1 antagonists by OHNMACHT, Cyrus J, ALBERT, Jeffrey S, BERNSTEIN, Peter R, RUMSEY, William L, MASEK, Brian B, DEMBOFSKY, Bruce T, KOETHER, Gerard M, ANDISIK, Donald W, AHARONY, David

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Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency... by Edwards, Philip D, Albert, Jeffrey S, Sylvester, Mark, Aharony, David, Andisik, Donald, Callaghan, Owen, Campbell, James B, Carr, Robin A, Chessari, Gianni, Congreve, Miles, Frederickson, Martyn, Folmer, Rutger H. A, Geschwindner, Stefan, Koether, Gerard, Kolmodin, Karin, Krumrine, Jennifer, Mauger, Russell C, Murray, Christopher W, Olsson, Lise-Lotte, Patel, Sahil, Spear, Nate, Tian, Gaochao

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Discovery of novel, orally active dual NK1/NK2 antagonists by BERNSTEIN, Peter R, AHARONY, David, KOSMIDER, Benedict J, KIRKLAND, Karin, OHNMACHT, Cyrus J, POTTS, William, RUMSEY, William L, LIHONG SHEN, SHENVI, Ashok, SHERWOOD, Scott, STOLLMAN, David, RUSSELL, Keith, ALBERT, Jeffrey S, ANDISIK, Donald, BARTHLOW, Herbert G, BIALECKI, Russell, DAVENPORT, Timothy, DEDINAS, Robert F, DEMBOFSKY, Bruce T, KOETHER, Gerard

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Design and optimization of cyclized NK 1 antagonists with controlled atropisomeric properties by Albert, Jeffrey S, Ohnmacht, Cyrus, Bernstein, Peter R, Rumsey, William L, Aharony, David, Masek, Brian B, Dembofsky, Bruce T, Koether, Gerard M, Potts, William, Evenden, John L

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Naphtho[2,1- b][1,5] and [1,2- f][1,4]oxazocines as selective NK 1 antagonists by Ohnmacht, Cyrus J., Albert, Jeffrey S., Bernstein, Peter R., Rumsey, William L., Masek, Brian B., Dembofsky, Bruce T., Koether, Gerard M., Andisik, Donald W., Aharony, David

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Design, synthesis, and SAR of tachykinin antagonists: modulation of balance in NK(1)/NK(2) receptor antagonist activity by Albert, Jeffrey S, Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R, Bialecki, Russell A, Dedinas, Robert, Dembofsky, Bruce T, Hill, Daniel, Kirkland, Karin, Koether, Gerard M, Kosmider, Benedict J, Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J, Russell, Keith

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Design, Synthesis, and SAR of Tachykinin Antagonists:  Modulation of Balance in NK 1 /NK 2 Receptor Antagonist Activity by Albert, Jeffrey S., Aharony, David, Andisik, Donald, Barthlow, Herbert, Bernstein, Peter R., Bialecki, Russell A., Dedinas, Robert, Dembofsky, Bruce T., Hill, Daniel, Kirkland, Karin, Koether, Gerard M., Kosmider, Benedict J., Ohnmacht, Cyrus, Palmer, William, Potts, William, Rumsey, William, Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Warwick, Paul J., Russell, Keith

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Discovery of novel, orally active dual NK 1/NK 2 antagonists by Bernstein, Peter R., Aharony, David, Albert, Jeffrey S., Andisik, Donald, Barthlow, Herbert G., Bialecki, Russell, Davenport, Timothy, Dedinas, Robert F., Dembofsky, Bruce T., Koether, Gerard, Kosmider, Benedict J., Kirkland, Karin, Ohnmacht, Cyrus J., Potts, William, Rumsey, William L., Shen, Lihong, Shenvi, Ashok, Sherwood, Scott, Stollman, David, Russell, Keith

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