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Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design
by
Chitty, Jessica L.
,
Blake, Kirsten L.
,
Blundell, Ross D.
,
Koh, Y.Q.Andre E.
,
Thompson, Merinda
,
Robertson, Avril A.B.
,
Butler, Mark S.
,
Cooper, Matthew A.
,
Kappler, Ulrike
,
Williams, Simon J.
,
Kobe, Bostjan
,
Fraser, James A.
Published in
The Journal of biological chemistry
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The Journal Of Biological Chemistry
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Subjects
Adenylosuccinate Lyase
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Adenylosuccinate Lyase - Antagonists & Inhibitors
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Adenylosuccinate Lyase - Chemistry
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Adenylosuccinate Lyase - Genetics
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Adenylosuccinate Lyase - Metabolism
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Amino Acid Sequence
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Animals
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Antifungal Agents - Chemistry
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Antifungal Agents - Pharmacology
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Antifungal Agents - Therapeutic Use
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Binding Sites
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Biochemistry & Molecular Biology
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Cryptococcosis - Drug Therapy
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Cryptococcosis - Metabolism
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Cryptococcosis - Microbiology
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Cryptococcus Neoformans - Drug Effects
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Cryptococcus Neoformans - Enzymology
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Cryptococcus Neoformans - Genetics
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Cryptococcus Neoformans - Pathogenicity
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Crystal Structure
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Freely Accessible Science Journals - Check A-Z Of Ejournals
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Doaj Directory Of Open Access Journals
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Free Full-Text Journals In Chemistry
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