Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations by Ljungström, Viktor, Cortese, Diego, Young, Emma, Pandzic, Tatjana, Mansouri, Larry, Plevova, Karla, Ntoufa, Stavroula, Baliakas, Panagiotis, Clifford, Ruth, Sutton, Lesley-Ann, Blakemore, Stuart J., Stavroyianni, Niki, Agathangelidis, Andreas, Rossi, Davide, Höglund, Martin, Kotaskova, Jana, Juliusson, Gunnar, Belessi, Chrysoula, Chiorazzi, Nicholas, Panagiotidis, Panagiotis, Langerak, Anton W., Smedby, Karin E., Oscier, David, Gaidano, Gianluca, Schuh, Anna, Davi, Frederic, Pott, Christiane, Strefford, Jonathan C., Trentin, Livio, Pospisilova, Sarka, Ghia, Paolo, Stamatopoulos, Kostas, Sjöblom, Tobias, Rosenquist, Richard

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The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte Migration by KAUCKA, Markéta, PLEVOVA, Karla, TICHY, Boris, BRYCHTOVA, Yvona, DOUBEK, Michael, KOZUBIK, Alois, MAYER, Jiří, POSPISILOVA, Sarka, BRYJA, Vítĕzslav, PAVLOVA, Sarka, JANOVSKA, Pavlina, MISHRA, Archana, VERNER, Jan, PROCHAZKOVA, Jiřina, KREJCI, Pavel, KOTASKOVA, Jana, OVESNA, Petra

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Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing by Kurucova, Terezia, Reblova, Kamila, Janovska, Pavlina, Porc, Jakub Pawel, Navrkalova, Veronika, Pavlova, Sarka, Malcikova, Jitka, Plevova, Karla, Tichy, Boris, Doubek, Michael, Bryja, Vitezslav, Kotaskova, Jana, Pospisilova, Sarka

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The importance of complex karyotype in prognostication and treatment of chronic lymphocytic leukemia (CLL): a comprehensive review of the literature by Jarošová, Marie, Plevová, Karla, Kotašková, Jana, Doubek, Michael, Pospíšilová, Šárka

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Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene by Poppova, Lucie, Pavlova, Sarka, Gonzalez, Beatriz, Kotaskova, Jana, Plevova, Karla, Dumbovic, Gabrijela, Janovska, Pavlina, Bystry, Vojtech, Panovska, Anna, Bezdekova, Lucie, Maslejova, Stanislava, Brychtova, Yvona, Doubek, Michael, Krzyzankova, Marcela, Borsky, Marek, Mayer, Jiri, Bryja, Vitezslav, Alonso, Sergio, Pospisilova, Sarka

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Evolution of TP53 abnormalities during CLL disease course is associated with telomere length changes by Olbertova, Helena, Plevova, Karla, Pavlova, Sarka, Malcikova, Jitka, Kotaskova, Jana, Stranska, Kamila, Spunarova, Michaela, Trbusek, Martin, Navrkalova, Veronika, Dvorackova, Barbara, Tom, Nikola, Pal, Karol, Jarosova, Marie, Brychtova, Yvona, Panovska, Anna, Doubek, Michael, Pospisilova, Sarka

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Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells by Dave, Zankruti, Vondálová Blanářová, Olga, Čada, Štěpán, Janovská, Pavlína, Zezula, Nikodém, Běhal, Martin, Hanáková, Kateřina, Ganji, Sri Ranjani, Krejci, Pavel, Gömöryová, Kristína, Peschelová, Helena, Šmída, Michal, Zdráhal, Zbyněk, Pavlová, Šárka, Kotašková, Jana, Pospíšilová, Šárka, Bryja, Vítězslav

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P1517: HUMORAL AND CELLULAR IMMUNE RESPONSES TO SARS‐COV‐2 NATURAL INFECTION OR VACCINATION IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): A STUDY BY ERIC, THE EUROPEAN RESEA... by Campanella, Alessandro, Capasso, Antonella, Taccetti, Caterina, Heltai, Silvia, Albi, Elisa, Herishanu, Yair, Haggenburg, Sabine, Chatzikonstantinou, Thomas, Doubek, Michael, Kättström, Magdalena, Giannopoulos, Krzysztof, Simkovic, Martin, Moreno, Carol, Massaia, Massimo, Bumbea, Horia, Shimmari, Salem Al, Ranghetti, Pamela, Perotta, Eleonora, Martini, Francesca, Sant’antonio, Emanuela, Colia, Maria, Combi, Catalina, Levi, Shai, Kater, Arnon, Hazenberg, Mette, Nijhof, Inger, Hofsink, Quincy, Demosthenous, Christos, Kotaskova, Jana, Zaleska, Joanna, Vrbacky, Filip, Mora, Alba, Bisogno, Davide, Tripoli, Ignazio Ezio, Popov, Viola Maria, Roman, Viviana, Scarano, Eloise, Frenquelli, Michela, Scarfò, Lydia, Stamatopoulos, Kostas, Ghia, Paolo

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Chronic lymphocytic leukemia: A prognostic model comprising only two biomarkers (IGHV mutational status and FISH cytogenetics) separates patients with different outcome and simplif... by Delgado, Julio, Doubek, Michael, Baumann, Tycho, Kotaskova, Jana, Molica, Stefano, Mozas, Pablo, Rivas‐Delgado, Alfredo, Morabito, Fortunato, Pospisilova, Sarka, Montserrat, Emili

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Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options by Malcikova, Jitka, Pavlova, Sarka, Kunt Vonkova, Barbara, Radova, Lenka, Plevova, Karla, Kotaskova, Jana, Pal, Karol, Dvorackova, Barbara, Zenatova, Marcela, Hynst, Jakub, Ondrouskova, Eva, Panovska, Anna, Brychtova, Yvona, Zavacka, Kristyna, Tichy, Boris, Tom, Nikola, Mayer, Jiri, Doubek, Michael, Pospisilova, Sarka

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Integrative NGS testing reveals clonal dynamics of adverse genomic defects contributing to a natural progression in treatment-naïve CLL patients by Navrkalova, Veronika, Plevova, Karla, Radova, Lenka, Porc, Jakub, Pal, Karol, Malcikova, Jitka, Pavlova, Sarka, Doubek, Michael, Panovska, Anna, Kotaskova, Jana, Pospisilova, Sarka

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International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia by Condoluci, Adalgisa, Terzi di Bergamo, Lodovico, Langerbeins, Petra, Hoechstetter, Manuela A., Herling, Carmen D., De Paoli, Lorenzo, Delgado, Julio, Rabe, Kari G., Gentile, Massimo, Doubek, Michael, Mauro, Francesca R., Chiodin, Giorgia, Mattsson, Mattias, Bahlo, Jasmin, Cutrona, Giovanna, Kotaskova, Jana, Deambrogi, Clara, Smedby, Karin E., Spina, Valeria, Bruscaggin, Alessio, Wu, Wei, Moia, Riccardo, Bianchi, Elena, Gerber, Bernhard, Zucca, Emanuele, Gillessen, Silke, Ghielmini, Michele, Cavalli, Franco, Stussi, Georg, Hess, Mark A., Baumann, Tycho S., Neri, Antonino, Ferrarini, Manlio, Rosenquist, Richard, Forconi, Francesco, Foà, Robin, Pospisilova, Sarka, Morabito, Fortunato, Stilgenbauer, Stephan, Döhner, Hartmut, Parikh, Sameer A., Wierda, William G., Montserrat, Emili, Gaidano, Gianluca, Hallek, Michael, Rossi, Davide

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ROR1‐based immunomagnetic protocol allows efficient separation of CLL and healthy B cells by Kotašková, Jana, Pavlová, Šárka, Greif, Igor, Stehlíková, Olga, Plevová, Karla, Janovská, Pavlína, Brychtová, Yvona, Doubek, Michael, Pospíšilová, Šárka, Bryja, Vítězslav

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Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference by Baliakas, Panagiotis, Puiggros, Anna, Xochelli, Aliki, Sutton, Lesley-Ann, Nguyen-Khac, Florence, Gardiner, Anne, Plevova, Karla, Minga, Eva, Hadzidimitriou, Anastasia, Walewska, Renata, McCarthy, Helen, Ortega, Margarita, Collado, Rosa, González, Teresa, Granada, Isabel, Luño, Elisa, Kotašková, Jana, Moysiadis, Theodoros, Davis, Zadie, Stavroyianni, Niki, Anagnostopoulos, Achilles, Strefford, Jonathan C, Pospisilova, Sarka, Davi, Frederic, Athanasiadou, Anastasia, Rosenquist, Richard, Oscier, David, Espinet, Blanca, Stamatopoulos, Kostas

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Survival Outcomes of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) Treated in the Chemoimmunotherapy Vs BTK Inhibitor (BTKi) Eras: A European Research Initia... by C, T, Minga, Eva, Karakatsoulis, Georgios, Albi, Elisa, Alcoceba, Miguel, Allsup, David, Bacchiarri, Francesca, Besikli-Dimou, Sotiria, Chatzileontiadou, Sofia, Collado, Rosa, Davis, Zadie, Dimou, Maria, Donaldson, David, Efstathopoulou, Maria, Galimberti, Sara, Galitzia, Andrea, Gimeno, Eva, Guarente, Valerio, Hatzimichael, Eleftheria, Hernandez-Rivas, Jose-Angel, Iacoboni, Gloria, Konstantinou, Iliana, Kotsianidis, Ioannis, Kotaskova, Jana, Koumpis, Andreas Epameinondas, Kubova, Zuzana, Labrador, Jorge, Laurenti, Luca, Marquet, Juan, Maslejova, Stanislava, Mayor-Bastida, Carlota, Miras, Fatima, Moia, Riccardo, Navarro-Bailon, Almudena, Olivieri, Jacopo, Papaioannou, Maria, Puiggros, Anna, Rigolin, Gian Matteo, Schipani, Mattia, Shokralla, Tereza, Simkovic, Martin, Tranidou, Antigoni, Vassilakopoulos, Theodoros, Visentin, Andrea, Vitale, Candida, Vrachiolias, George, Walewska, Renata, Yanez San Segundo, Lucrecia, Zuchnicka, Jana, Oscier, David Graham, Gozzetti, Alessandro, Panayiotidis, Panayiotis, Bosch, Francesc, Sportoletti, Paolo, Espinet, Blanca, Pangalis, Gerassimos, Angelopoulou, Maria, Papajik, Tomas, Murru, Roberta, Coscia, Marta, Cuneo, Antonio, Gaidano, Gianluca, Stavrogianni, Niki, Trentin, Livio, Smolej, Lukas, Caterwood, Mark, Spacek, Martin, Pospisilova, Sarka, Doubek, Michael, Chatzidimitriou, Anastasia, Stamatopoulos, Kostas, Ghia, Paolo, Scarfo, Lydia

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Enabling the Implementation of Next-Generation Sequencing into Clinical Diagnosis: Nemhesys Project by Hernández-Rivas, Jesús María, Serramito-Gómez, Inmaculada, Kallio, Saara, Cantalejo, Amparo, Kotaskova, Jana, Rodriguez, Ana E., Abáigar, María, Benito, Rocio, Dolnik, Anna, Catherwood, Mark, Blayney, Jaine, Tichý, Boris, Chalupová, Ivana, Dubois, Philippe, Lopez, Roberto, Barranquero, Carlos, Lorenzo, María Díaz, Leitzelman, Mylène, Adhikari, Sadiksha, Pospíšilová, Šárka, Bullinger, Lars, Mills, Ken I, Heckman, Caroline A.

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CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase by Hernández-Sánchez, María, Kotaskova, Jana, Rodríguez, Ana E, Radova, Lenka, Tamborero, David, Abáigar, María, Plevova, Karla, Benito, Rocío, Tom, Nikola, Quijada-Álamo, Miguel, Bikos, Vasileos, Martín, Ana África, Pal, Karol, García de Coca, Alfonso, Doubek, Michael, López-Bigas, Nuria, Hernández-Rivas, Jesús-María, Pospisilova, Sarka

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Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY (Dec, 10.103... by Mansouri, L, Thorvaldsdottir, B, Sutton, L-A, Karakatsoulis, G, Meggendorfer, M, Parker, H, Nadeu, F, Brieghel, C, Laidou, S, Moia, R

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CLL: A Prognostic Model Comprising Only Two Biomarkers (IGHV Mutational Status and FISH-Cytogenetics) Separates Patients with Different Prognosis and Simplifies the CLL-IPI by Delgado, Julio, Doubek, Michael, Baumann, Tycho, Kotaskova, Jana, Mozas, Pablo, Rivas-Delgado, Alfredo, Pospisilova, Sarka, Montserrat, Emili

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Decreased WNT3 expression in chronic lymphocytic leukaemia is a hallmark of disease progression and identifies patients with worse prognosis in the subgroup with mutated IGHV by Poppova, Lucie, Janovska, Pavlina, Plevova, Karla, Radova, Lenka, Plesingerova, Hana, Borsky, Marek, Kotaskova, Jana, Kantorova, Barbara, Hlozkova, Michaela, Figulova, Jana, Brychtova, Yvona, Machalova, Michaela, Urik, Milan, Doubek, Michael, Kozubik, Alois, Pospisilova, Sarka, Pavlova, Sarka, Bryja, Vitezslav

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