A Phase 1 randomized, open‐label clinical trial to evaluate the effect of a far‐infrared emitting patch on local skin perfusion, microcirculation and oxygenation by Kraaij, Sebastiaan J. W., Hamblin, Michael R., Pickering, Gisele, Giannokopoulos, Bill, Kechemir, Hayet, Heinz, Moritz, Igracki‐Turudic, Iva, Yavuz, Yalçin, Rissmann, Robert, Gal, Pim

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Randomized placebo‐controlled crossover study to assess tolerability and pharmacodynamics of zagociguat, a soluble guanylyl cyclase stimulator, in healthy elderly by Kraaij, Sebastiaan J. W., Borghans, Laura, Klaassen, Erica S., Gal, Pim, Grond, Jeroen, Tripp, Ken, Winrow, Christopher, Glasser, Chad, Groeneveld, Geert Jan

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First‐in‐human trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of zagociguat (CY6463), a CNS‐penetrant soluble guanylyl cyclase stimulator by Kraaij, Sebastiaan J. W., Gal, Pim, Borghans, Laura G. J. M., Klaassen, Erica S., Dijkstra, Francis, Winrow, Christopher, Glasser, Chad, Groeneveld, Geert Jan

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Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study by in ‘t Veld, Aliede E., Grievink, Hendrika W., van der Plas, Johan L., Eveleens Maarse, Boukje C., van Kraaij, Sebastiaan J. W., Woutman, Tess D., Schoonakker, Mascha, Klarenbeek, Naomi B., de Kam, Marieke L., Kamerling, Ingrid M. C., Jansen, Manon A. A., Moerland, Matthijs

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Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease by Kraaij, Sebastiaan J. W., Pereira, Diana R., Smal, Bastiaan, Summo, Luciana, Konkel, Anne, Lossie, Janine, Busjahn, Andreas, Grammatopoulos, Tom N., Klaassen, Erica, Fischer, Robert, Schunck, Wolf‐Hagen, Gal, Pim, Moerland, Matthijs

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Effects of the phosphodiesterase 2 inhibitor BI 474121 on central nervous system cyclic guanosine monophosphate concentrations: Translational studies by Kraaij, Sebastiaan, Goeldner, Rainer‐Georg, Rosenbrock, Holger, Groeneveld, Geert Jan, Kremer, Philip, Schaible, Jennifer, Zambori, Janos, Schultheis, Christian

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Impact of fibre supplementation on microbiome and resilience in healthy participants: A randomized, placebo-controlled clinical trial by Eveleens Maarse, Boukje C., Eggink, Hannah M., Warnke, Ines, Bijlsma, Sabina, van den Broek, Tim J., Oosterman, Johanneke E., Caspers, Martien P.M., Sybesma, Wilbert, Gal, Pim, van Kraaij, Sebastiaan J.W., Schuren, Frank H.J., Moerland, Matthijs, Hoevenaars, Femke P.M.

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Microvascular effects of a mixed meal tolerance test: a model validation study by van Kraaij, Sebastiaan J W, Eveleens Maarse, Boukje Charlotte, Hoevenaars, Femke P M, Warnke, Ines, de Kam, Marieke L, Moerland, Matthijs, Gal, Pim

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Cognitive Effects of Three β-Adrenoceptor Acting Drugs in Healthy Volunteers and Patients with Parkinson’s Disease by Eijsvogel, Pepijn P.N.M., Borghans, Laura G.J.M., Prins, Samantha, Moss, Laurence, van Kraaij, Sebastiaan J.W., van Brummelen, Emilie, Klaassen, Erica, Martin, Renee S., Bautista, Edgar, Ford, Anthony P., Kremer, Philip H.C., Groeneveld, Geert Jan, Vargas, Gabriel A.

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Open-Label Interventional Study in Healthy Volunteers to Evaluate NO-Mediated Vasodilation by Dermal Allyl Isothiocyanate Challenge and Whole-Body Heat Stress by van Ruissen, Marella C E, van Kraaij, Sebastiaan J W, Gal, Pim, Bakker, Wouter A, Hijma, Hemme J, Groeneveld, Geert Jan, de Kam, Marieke L, Burggraaf, Jacobus, Moerland, Matthijs

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Safety of low-volume PEG-asc bowel cleansing preparation for colonoscopy: identifying patients at risk for hypokalemia in a prospective cohort study by Reumkens, Ankie, Bakker, Christine Minke, van Kraaij, Sebastiaan J.W., Winkens, Bjorn, Raijmakers, Maarten T., van Nunen, Annick B., van Deursen, Cees Th.B.M., Masclee, Ad A.M.

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