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Assessing the Impact of Charge Variants on Stability and Viscosity of a High Concentration Antibody Formulation
by
Sule, Shantanu V.
,
Fernandez, Jason E.
,
Mecozzi, Vincent J.
,
Kravets, Yana
,
Yang, William C.
,
Feng, Pamela
,
Liu, Suli
,
Zang, Li
,
Capili, Allan D.
,
Estey, Tia B.
,
Gupta, Kapil
Published in
Journal of pharmaceutical sciences
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Journal Of Pharmaceutical Sciences
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Subjects
Acids - Chemistry
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Antibodies, Monoclonal - Chemistry
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Biotechnology
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Charge Isoforms
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Chemistry
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Chemistry, Medicinal
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Chemistry, Multidisciplinary
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Chemistry, Pharmaceutical - Methods
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High Concentration
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Humans
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Immunoglobulin G - Chemistry
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Isoelectric Point
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Life Sciences & Biomedicine
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Monoclonal Antibodies
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Pharmacology & Pharmacy
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Physical Sciences
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Physical Stability
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Protein Aggregation
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Protein Characterization
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Protein Formulation
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Wiley-Blackwell Journals
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