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Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry dis...
by
Martínez-Bailén, Macarena
,
Carmona, Ana T.
,
Cardona, Francesca
,
Matassini, Camilla
,
Goti, Andrea
,
Kubo, Moemi
,
Kato, Atsushi
,
Robina, Inmaculada
,
Moreno-Vargas, Antonio J.
Published in
European journal of medicinal chemistry
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Exploring substituent diversity on pyrrolidine-aryltriazole iminosugars: Structural basis of β-glucocerebrosidase inhibition
by
Martínez-Bailén, Macarena
,
Carmona, Ana T.
,
Patterson-Orazem, Athéna C.
,
Lieberman, Raquel L.
,
Ide, Daisuke
,
Kubo, Moemi
,
Kato, Atsushi
,
Robina, Inmaculada
,
Moreno-Vargas, Antonio J.
Published in
Bioorganic chemistry
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Journal Title
Bioorganic Chemistry
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European Journal Of Medicinal Chemistry
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Subjects
Dose-Response Relationship, Drug
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Enzyme Inhibitors - Chemical Synthesis
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Enzyme Inhibitors - Chemistry
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Enzyme Inhibitors - Pharmacology
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Glucosylceramidase - Antagonists & Inhibitors
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Glucosylceramidase - Metabolism
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Humans
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Imino Sugars - Chemical Synthesis
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Imino Sugars - Chemistry
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Imino Sugars - Pharmacology
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Iminosugars
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Life Sciences & Biomedicine
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Molecular Structure
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Pyrrolidines - Chemistry
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Pyrrolidines - Pharmacology
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Science & Technology
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Structure-Activity Relationship
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Β-Glucocerebrosidase Inhibitors
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Alpha-Galactosidase - Antagonists & Inhibitors
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Alpha-Galactosidase - Metabolism
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Sciencedirect Journals
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Sciencedirect Freedom Collection
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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