AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer by Kubli, Shawn P., Bassi, Christian, Roux, Cecilia, Wakeham, Andrew, Göbl, Christoph, Zhou, Wenjing, Jafari, Soode Moghadas, Snow, Bryan, Jones, Lisa, Palomero, Luis, Thu, Kelsie L., Cassetta, Luca, Soong, Daniel, Berger, Thorsten, Ramachandran, Parameswaran, Baniasadi, Shakiba P., Duncan, Gordon, Lindzen, Moshit, Yarden, Yosef, Herranz, Carmen, Lazaro, Conxi, Chu, Mandy F., Haight, Jillian, Tinto, Paul, Silvester, Jennifer, Cescon, David W., Petit, Anna, Pettersson, Sven, Pollard, Jeffrey W., Mak, Tak W., Pujana, Miguel A., Cappello, Paola, Gorrini, Chiara

Get full text

Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer by Bolton, Kelly L, Chenevix- Trench, Georgia, Goh, Cindy, Sadetzki, Siegal, Ramus, Susan J, Karlan, Beth Y, Lambrechts, Diether, Despierre, Evelyn, Barrowdale, Daniel, McGuffog, Lesley, Healey, Sue, Easton, Douglas F, Sinilnikova, Olga, Benítez, Javier, García, María J, Neuhausen, Susan, Gail, Mitchell H, Hartge, Patricia, Peock, Susan, Frost, Debra, Evans, D. Gareth, Eeles, Rosalind, Godwin, Andrew K, Daly, Mary B, Kwong, Ava, Ma, Edmond S. K, Lázaro, Conxi, Blanco, Ignacio, Montagna, Marco, D'Andrea, Emma, Nicoletto, Maria Ornella, Johnatty, Sharon E, Kjær, Susanne Krüger, Jensen, Allan, Høgdall, Estrid, Goode, Ellen L, Fridley, Brooke L, Loud, Jennifer T, Greene, Mark H, Mai, Phuong L, Chetrit, Angela, Lubin, Flora, Hirsh-Yechezkel, Galit, Glendon, Gord, Andrulis, Irene L, Toland, Amanda E, Senter, Leigha, Gore, Martin E, Gourley, Charlie, Michie, Caroline O, Song, Honglin, Tyrer, Jonathan, Whittemore, Alice S, McGuire, Valerie, Sieh, Weiva, Kristoffersson, Ulf, Olsson, Håkan, Borg, Åke, Levine, Douglas A, Steele, Linda, Beattie, Mary S, Chan, Salina, Nussbaum, Robert L, Moysich, Kirsten B, Gross, Jenny, Cass, Ilana, Walsh, Christine, Li, Andrew J, Leuchter, Ronald, Gordon, Ora, Garcia-Closas, Montserrat, Gayther, Simon A, Chanock, Stephen J, Antoniou, Antonis C, Pharoah, Paul D. P, EMBRACE, kConFab Investigators, and The Cancer Genome Atlas Research Network, for the

Get full text

Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation by Biayna, Josep, Mazuelas, Helena, Gel, Bernat, Terribas, Ernest, Dumbovic, Gabrijela, Rosas, Inma, Fernández-Rodriguez, Juana, Blanco, Ignacio, Castellanos, Elisabeth, Carrió, Meritxell, Lazaro, Conxi, Serra, Eduard

Get full text

Editorial: Hereditary Breast and Ovarian Cancer: Current Concepts of Prevention and Treatment by Grabenstetter, Anne, Lazaro, Conxi, Turashvili, Gulisa

Get full text

Multigene panel testing for hereditary breast and ovarian cancer in the province of Ontario by Lerner-Ellis, Jordan, Mighton, Chloe, Lazaro, Conxi, Watkins, Nicholas, Di Gioacchino, Vanessa, Wong, Andrew, Chang, Martin C., Charames, George S.

Get full text

Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors by Lahiguera, Álvaro, Hyroššová, Petra, Figueras, Agnès, Garzón, Diana, Moreno, Roger, Soto‐Cerrato, Vanessa, McNeish, Iain, Serra, Violeta, Lazaro, Conxi, Barretina, Pilar, Brunet, Joan, Menéndez, Javier, Matias‐Guiu, Xavier, Vidal, August, Villanueva, Alberto, Taylor‐Harding, Barbie, Tanaka, Hisashi, Orsulic, Sandra, Junza, Alexandra, Yanes, Oscar, Muñoz‐Pinedo, Cristina, Palomero, Luís, Pujana, Miquel Àngel, Perales, José Carlos, Viñals, Francesc

Get full text

Evaluation of CNV detection tools for NGS panel data in genetic diagnostics by Moreno-Cabrera, José Marcos, Del Valle, Jesús, Castellanos, Elisabeth, Feliubadaló, Lidia, Pineda, Marta, Brunet, Joan, Serra, Eduard, Capellà, Gabriel, Lázaro, Conxi, Gel, Bernat

Get full text

Correction to: Multigene panel testing for hereditary breast and ovarian cancer in the province of Ontario by Lerner-Ellis, Jordan, Mighton, Chloe, Lazaro, Conxi, Watkins, Nicholas, Di Gioacchino, Vanessa, Wong, Andrew, Chang, Martin C., Charames, George S.

Get full text

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor by Peterlongo, Paolo, Catucci, Irene, Colombo, Mara, Caleca, Laura, Mucaki, Eliseos, Bogliolo, Massimo, Marin, Maria, Damiola, Francesca, Bernard, Loris, Pensotti, Valeria, Volorio, Sara, Dall'Olio, Valentina, Meindl, Alfons, Bartram, Claus, Sutter, Christian, Surowy, Harald, Sornin, Valérie, Dondon, Marie-Gabrielle, Eon-Marchais, Séverine, Stoppa-Lyonnet, Dominique, Andrieu, Nadine, Sinilnikova, Olga M, Mitchell, Gillian, James, Paul A, Thompson, Ella, Marchetti, Marina, Verzeroli, Cristina, Tartari, Carmen, Capone, Gabriele Lorenzo, Putignano, Anna Laura, Genuardi, Maurizio, Medici, Veronica, Marchi, Isabella, Federico, Massimo, Tognazzo, Silvia, Matricardi, Laura, Agata, Simona, Dolcetti, Riccardo, Della Puppa, Lara, Cini, Giulia, Gismondi, Viviana, Viassolo, Valeria, Perfumo, Chiara, Mencarelli, Maria Antonietta, Baldassarri, Margherita, Peissel, Bernard, Roversi, Gaia, Silvestri, Valentina, Rizzolo, Piera, Spina, Francesca, Vivanet, Caterina, Tibiletti, Maria Grazia, Caligo, Maria Adelaide, Gambino, Gaetana, Tommasi, Stefania, Pilato, Brunella, Tondini, Carlo, Corna, Chiara, Bonanni, Bernardo, Barile, Monica, Osorio, Ana, Benitez, Javier, Balestrino, Luisa, Ottini, Laura, Manoukian, Siranoush, Pierotti, Marco A, Renieri, Alessandra, Varesco, Liliana, Couch, Fergus J, Wang, Xianshu, Devilee, Peter, Hilbers, Florentine S, van Asperen, Christi J, Viel, Alessandra, Montagna, Marco, Cortesi, Laura, Diez, Orland, Balmaña, Judith, Hauke, Jan, Schmutzler, Rita K, Papi, Laura, Pujana, Miguel Angel, Lázaro, Conxi, Falanga, Anna, Offit, Kenneth, Vijai, Joseph, Campbell, Ian, Burwinkel, Barbara, Kvist, Anders, Ehrencrona, Hans, Mazoyer, Sylvie, Pizzamiglio, Sara, Verderio, Paolo, Surralles, Jordi, Rogan, Peter K, Radice, Paolo

Get full text

CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions by Herrera-Pariente, Cristina, Bonjoch, Laia, Muñoz, Jenifer, Fernàndez, Guerau, Soares de Lima, Yasmin, Mahmood, Romesa, Cuatrecasas, Miriam, Ocaña, Teresa, Lopez-Prades, Sandra, Llargués-Sistac, Gemma, Domínguez-Rovira, Xavier, Llach, Joan, Luzko, Irina, Díaz-Gay, Marcos, Lazaro, Conxi, Brunet, Joan, Castillo-Manzano, Carmen, García-González, María Asunción, Lanas, Angel, Carrillo, Marta, Hernández San Gil, Raquel, Quintero, Enrique, Sala, Nuria, Llort, Gemma, Aguilera, Lara, Carot, Laura, Diez-Redondo, Pilar, Jover, Rodrigo, Ramon y Cajal, Teresa, Cubiella, Joaquín, Castells, Antoni, Balaguer, Francesc, Bujanda, Luis, Castellví-Bel, Sergi, Moreira, Leticia

Get full text

Haplotype analysis of the internationally distributed BRCA1 c.3331_3334delCAAG founder mutation reveals a common ancestral origin in Iberia by Tuazon, Anna Marie De Asis, Lott, Paul, Bohórquez, Mabel, Benavides, Jennyfer, Ramirez, Carolina, Criollo, Angel, Estrada-Florez, Ana, Mateus, Gilbert, Velez, Alejandro, Carmona, Jenny, Olaya, Justo, Garcia, Elisha, Polanco-Echeverry, Guadalupe, Stultz, Jacob, Alvarez, Carolina, Tapia, Teresa, Ashton-Prolla, Patricia, Vega, Ana, Lazaro, Conxi, Tornero, Eva, Martinez-Bouzas, Cristina, Infante, Mar, De La Hoya, Miguel, Diez, Orland, Browning, Brian L, Rannala, Bruce, Teixeira, Manuel R, Carvallo, Pilar, Echeverry, Magdalena, Carvajal-Carmona, Luis G

Get full text

Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis by Gausachs, Mireia, Borras, Ester, Chang, Kyle, Gonzalez, Sara, Azuara, Daniel, Delgado Amador, Axel, Lopez-Doriga, Adriana, San Lucas, F Anthony, Sanjuan, Xavier, Paules, Maria J, Taggart, Melissa W, Davies, Gareth E, Ehli, Erik A, Fowler, Jerry, Moreno, Victor, Pineda, Marta, You, Y Nancy, Lynch, Patrick M, Lazaro, Conxi, Navin, Nicholas E, Scheet, Paul A, Hawk, Ernest T, Capella, Gabriel, Vilar, Eduardo

Get full text

Modification of BRCA1-associated breast cancer risk by HMMR overexpression by Mateo, Francesca, He, Zhengcheng, Mei, Lin, de Garibay, Gorka Ruiz, Herranz, Carmen, García, Nadia, Lorentzian, Amanda, Baiges, Alexandra, Blommaert, Eline, Gómez, Antonio, Mirallas, Oriol, Garrido-Utrilla, Anna, Palomero, Luis, Espín, Roderic, Extremera, Ana I., Soler-Monsó, M. Teresa, Petit, Anna, Li, Rong, Brunet, Joan, Chen, Ke, Tan, Susanna, Eaves, Connie J., McCloskey, Curtis, Hakem, Razq, Khokha, Rama, Lange, Philipp F., Lázaro, Conxi, Maxwell, Christopher A., Pujana, Miquel Angel

Get full text

Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers by Walker, Logan C, Marquart, Louise, Pearson, John F, Wiggins, George A R, O'Mara, Tracy A, Parsons, Michael T, Barrowdale, Daniel, McGuffog, Lesley, Dennis, Joe, Benitez, Javier, Slavin, Thomas P, Radice, Paolo, Frost, Debra, Godwin, Andrew K, Meindl, Alfons, Schmutzler, Rita Katharina, Isaacs, Claudine, Peshkin, Beth N, Caldes, Trinidad, Hogervorst, Frans Bl, Lazaro, Conxi, Jakubowska, Anna, Montagna, Marco, Chen, Xiaoqing, Offit, Kenneth, Hulick, Peter J, Andrulis, Irene L, Lindblom, Annika, Nussbaum, Robert L, Nathanson, Katherine L, Chenevix-Trench, Georgia, Antoniou, Antonis C, Couch, Fergus J, Spurdle, Amanda B

Get full text

Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19 by Solanich, Xavier, Vargas-Parra, Gardenia, van der Made, Caspar I., Simons, Annet, Schuurs-Hoeijmakers, Janneke, Antolí, Arnau, del Valle, Jesús, Rocamora-Blanch, Gemma, Setién, Fernando, Esteller, Manel, van Reijmersdal, Simon V., Riera-Mestre, Antoni, Sabater-Riera, Joan, Capellá, Gabriel, van de Veerdonk, Frank L., van der Hoven, Ben, Corbella, Xavier, Hoischen, Alexander, Lázaro, Conxi

Get full text

The Average Cumulative Risks of Breast and Ovarian Cancer for Carriers of Mutations in BRCA1 and BRCA2 Attending Genetic Counseling Units in Spain by Milne, Roger L, Osorio, Ana, Cajal, Teresa Ramón Y, Vega, Ana, Llort, Gemma, de la Hoya, Miguel, Díez, Orland, Alonso, M Carmen, Lazaro, Conxi, Blanco, Ignacio, Sánchez-de-Abajo, Ana, Caldés, Trinidad, Blanco, Ana, Graña, Begoña, Durán, Mercedes, Velasco, Eladio, Chirivella, Isabel, Cardeñosa, Eva Esteban, Tejada, María-Isabel, Beristain, Elena, Miramar, María-Dolores, Calvo, María-Teresa, Martínez, Eduardo, Guillén, Carmen, Salazar, Raquel, San Román, Carlos, Antoniou, Antonis C, Urioste, Miguel, Benítez, Javier

Get full text

Response to letter entitled: Re: ERCC3 a new ovarian cancer susceptibility gene? by Stradella, Agostina, del Valle, Jesús, Brunet, Joan, Lázaro, Conxi

Get full text

Boosting care and knowledge about hereditary cancer: European Reference Network on Genetic Tumour Risk Syndromes by Vos, Janet R., Giepmans, Lisette, Röhl, Claas, Geverink, Nicoline, Hoogerbrugge, Nicoline

Get full text

DGCR8 and the six hit, three-step model of schwannomatosis by Nogué, Clara, Chong, Anne-Sophie, Grau, Elia, Han, HyeRim, Dorca, Eduard, Roca, Carla, Mosquera, Jose Luis, Lázaro, Conxi, Foulkes, William D., Brunet, Joan, Rivera, Barbara

Get full text

Computational Tools for Splicing Defect Prediction in Breast/Ovarian Cancer Genes: How Efficient Are They at Predicting RNA Alterations? by Moles-Fernández, Alejandro, Duran-Lozano, Laura, Montalban, Gemma, Bonache, Sandra, López-Perolio, Irene, Menéndez, Mireia, Santamariña, Marta, Behar, Raquel, Blanco, Ana, Carrasco, Estela, López-Fernández, Adrià, Stjepanovic, Neda, Balmaña, Judith, Capellá, Gabriel, Pineda, Marta, Vega, Ana, Lázaro, Conxi, de la Hoya, Miguel, Diez, Orland, Gutiérrez-Enríquez, Sara

Get full text