Search Results - LOCKER, Karen L

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  1. 1
    Higher Throughput Bioanalysis by Automation of a Protein Precipitation Assay Using a 96-Well Format with Detection by LC−MS/MS

    Higher Throughput Bioanalysis by Automation of a Protein Precipitation Assay Using a 96-Well Format with Detection by LC−MS/MS by Watt, Alan P, Morrison, Denise, Locker, Karen L, Evans, David C

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  2. 2
    Fluorination of 3-(3-(Piperidin-1-yl)propyl)indoles and 3-(3-(Piperazin-1-yl)propyl)indoles Gives Selective Human 5-HT1D Receptor Ligands with Improved Pharmacokinetic Profiles

    Fluorination of 3-(3-(Piperidin-1-yl)propyl)indoles and 3-(3-(Piperazin-1-yl)propyl)indoles Gives Selective Human 5-HT1D Receptor Ligands with Improved Pharmacokinetic Profiles by van Niel, Monique B, Collins, Ian, Beer, Margaret S, Broughton, Howard B, Cheng, Susan K. F, Goodacre, Simon C, Heald, Anne, Locker, Karen L, MacLeod, Angus M, Morrison, Denise, Moyes, Christopher R, O'Connor, Desmond, Pike, Andrew, Rowley, Michael, Russell, Michael G. N, Sohal, Balbinder, Stanton, Josephine A, Thomas, Steven, Verrier, Hugh, Watt, Alan P, Castro, José L

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  3. 3
    2-Aryl indole NK1 receptor antagonists : Optimisation of indole substitution

    2-Aryl indole NK1 receptor antagonists : Optimisation of indole substitution by COOPER, Laura C, CHICCHI, Gary G, WATT, Alan P, WILLIAMS, Angela R, SWAIN, Christopher J, DINNELL, Kevin, ELLIOTT, Jason M, HOLLINGWORTH, Gregory J, KURTZ, Mare M, LOCKER, Karen L, MORRISON, Denise, SHAW, Duncan E, TSAO, Kwei-Lan

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  4. 4
    Determination of the in vitro metabolism of (+)- and (−)-epibatidine

    Determination of the in vitro metabolism of (+)- and (−)-epibatidine by Watt, Alan P, Hitzel, Laure, Morrison, Denise, Locker, Karen L

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  5. 5
    Use of chiral liquid chromatography–tandem mass spectrometry to investigate the metabolism of racemic cholecystokinin-B antagonists

    Use of chiral liquid chromatography–tandem mass spectrometry to investigate the metabolism of racemic cholecystokinin-B antagonists by Watt, Alan P, Hitzel, Laure, Morrison, Denise, Locker, Karen L

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  6. 6
    An increased throughput method for the determination of partition coefficients

    An increased throughput method for the determination of partition coefficients by HITZEL, Laure, WATT, Alan P, LOCKER, Karen L

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  7. 7
    Quantitative determination of L-775,606, a selective 5-hydroxytryptamine 1D agonist, in rat plasma using automated sample preparation and detection by liquid chromatography-tandem mass spectrometry

    Quantitative determination of L-775,606, a selective 5-hydroxytryptamine 1D agonist, in rat plasma using automated sample preparation and detection by liquid chromatography-tandem... by LOCKER, Karen L, MORRISON, Denise, WATT, Alan P

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  8. 8
    2-Aryl Indole NK 1 receptor antagonists: optimisation of indole substitution

    2-Aryl Indole NK 1 receptor antagonists: optimisation of indole substitution by Cooper, Laura C., Chicchi, Gary G., Dinnell, Kevin, Elliott, Jason M., Hollingworth, Gregory J., Kurtz, Marc M., Locker, Karen L., Morrison, Denise, Shaw, Duncan E., Tsao, Kwei-Lan, Watt, Alan P., Williams, Angela R., Swain, Christopher J.

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  9. 9
    Fluorination of 3-(3-(Piperidin-1-yl)propyl)indoles and 3-(3-(Piperazin-1-yl)propyl)indoles Gives Selective Human 5-HT 1D Receptor Ligands with Improved Pharmacokinetic Profiles

    Fluorination of 3-(3-(Piperidin-1-yl)propyl)indoles and 3-(3-(Piperazin-1-yl)propyl)indoles Gives Selective Human 5-HT 1D Receptor Ligands with Improved Pharmacokinetic Profiles by van Niel, Monique B., Collins, Ian, Beer, Margaret S., Broughton, Howard B., Cheng, Susan K. F., Goodacre, Simon C., Heald, Anne, Locker, Karen L., MacLeod, Angus M., Morrison, Denise, Moyes, Christopher R., O'Connor, Desmond, Pike, Andrew, Rowley, Michael, Russell, Michael G. N., Sohal, Balbinder, Stanton, Josephine A., Thomas, Steven, Verrier, Hugh, Watt, Alan P., Castro, José L.

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  10. 10
    Patient‐centered outcomes in the POLO study of active maintenance olaparib for germline BRCA‐mutated metastatic pancreatic cancer

    Patient‐centered outcomes in the POLO study of active maintenance olaparib for germline BRCA‐mutated metastatic pancreatic cancer by Kindler, Hedy L., Yoo, Hyun Kyoo, Hettle, Robert, Cui, Karen Y., Joo, Seongjung, Locker, Gershon Y., Golan, Talia

    Published in Cancer
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  11. 11
    Substance P (Neurokinin 1) Receptor Antagonists Enhance Dorsal Raphe Neuronal Activity

    Substance P (Neurokinin 1) Receptor Antagonists Enhance Dorsal Raphe Neuronal Activity by Conley, Rachel K, Cumberbatch, Michael J, Mason, Glenn S, Williamson, David J, Harrison, Timothy, Locker, Karen, Swain, Christopher, Maubach, Karen, O'Donnell, Ruth, Rigby, Michael, Hewson, Louise, Smith, David, Rupniak, Nadia M. J

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