Understanding and modulating apoptosis in industrial cell culture by Laken, Haley A, Leonard, Mark W

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Preclinical gastrointestinal prokinetic efficacy and endocrine effects of the ghrelin mimetic RM-131 by Van der Ploeg, Lex, Laken, Haley, Sharma, Shubh, Datta, Rakesh, Halem, Heather, Dong, Jesse, Touvay, Caroline, Teillot, Marc, Noonan, Patrick, Tartaglia, Lou, Stoner, Liz, Henderson, Bart, Gottesdiener, Keith, Culler, Michael

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First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab: ICOS-High CD4 T-Cell Populations and Predictors of Response by Yap, Timothy A, Gainor, Justin F, Callahan, Margaret K, Falchook, Gerald S, Pachynski, Russell K, LoRusso, Patricia, Kummar, Shivaani, Gibney, Geoffrey T, Burris, Howard A, Tykodi, Scott S, Rahma, Osama E, Seiwert, Tanguy Y, Papadopoulos, Kyriakos P, Blum Murphy, Mariela, Park, Haeseong, Hanson, Amanda, Hashambhoy-Ramsay, Yasmin, McGrath, Lara, Hooper, Ellen, Xiao, Xiaoying, Cohen, Heather, Fan, Martin, Felitsky, Daniel, Hart, Courtney, McComb, Rachel, Brown, Karen, Sepahi, Ali, Jimenez, Judith, Zhang, Weidong, Baeck, Johan, Laken, Haley, Murray, Richard, Trehu, Elizabeth, Harvey, Christopher J

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Abstract A201: Discovery of TSR-033, a novel, potent anti-human LAG-3 therapeutic antibody by Ghosh, Srimoyee, Laken, Haley, Travers, Jon, Kamar, Sujatha, Jun, H. Toni, Kehry, Marilyn R., Jenkins, David

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Abstract 4053: Genetic and molecular profiling of ICOS hi CD4 T cells demonstrates clonal expansion of Th1 effector cells following JTX-2011 treatment in subjects with solid tumors by Harvey, Christopher, Hanson, Amanda, Fan, Martin, McGrath, Lara, Felitsky, Daniel, Johnson, Calvin, Lacey, Sean, Hirsch, Heather, Hooper, Ellen, McClure, Ty, Trehu, Elizabeth, Law, Deborah, Laken, Haley

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Abstract 5536: ICOS hi CD4 T cells emerging on vopratelimab treatment have Th1 central memory characteristics and may contribute to durability of clinical responses by Hanson, Amadna, Daneshwar, Abha, Cohen, Heather, Hashambhoy-Ramsay, Yasmin, O'Malley, Kristin, Bala, Krithi, McGrath, Lara, Leone, Kristen, Hart, Courtney, McComb, Rachel, Baeck, Johan, Hooper, Ellen, Trehu, Elizabeth, Laken, Haley, Gostissa, Monica, Harvey, Christopher

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First in Human Phase 1/2 ICONIC Trial of the ICOS agonist vopratelimab alone and with nivolumab: ICOS-hi CD4 T cell populations and predictors of response by Yap, Timothy A, Gainor, Justin F, Callahan, Margaret K, Falchook, Gerald S, Pachynski, Russell K, LoRusso, Patricia, Kummar, Shivaani, Gibney, Geoffrey T, Burris, Howard A, Tykodi, Scott S, Rahma, Osama E, Seiwert, Tanguy Y, Papadopoulos, Kyriakos P, Murphy, Mariela Blum, Park, Haeseong, Hanson, Amanda, Hashambhoy-Ramsay, Yasmin, McGrath, Lara, Hooper, Ellen, Xiao, Xiaoying, Cohen, Heather, Fan, Martin, Felitsky, Daniel, Hart, Courtney, McComb, Rachel, Brown, Karen, Sepahi, Ali, Jimenez, Judith, Zhang, Weidong, Baeck, Johan, Laken, Haley, Murray, Richard, Trehu, Elizabeth, Harvey, Christopher J

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Abstract CT189: Improved progression-free and overall survival (PFS/OS) in patients (pts) with emergence of JTX-2011 associated biomarker (ICOS high CD4 T cells) on the ICONIC tria... by Yap, Timothy Anthony, Gainor, Justin F., Callahan, Margaret K., Falchook, Gerald S., Pachynski, Russell Kent, LoRusso, Patricia, Kummar, Shivaani, Gibney, Geoffrey Thomas, Burris, Howard A., Tykodi, Scott S., Rahma, Osama E., Seiwert, Tanguy, Papadopoulos, Kyriakos P., Hooper, Ellen, Harvey, Christopher J., Hanson, Amanda, Lacey, Sean, McComb, Rachel, Hart, Courtney, Laken, Haley, McClure, Ty, Trehu, Elizabeth

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Abstract 271: Targeting PD-1, TIM-3 and LAG-3 in combination for improved immunotherapy combinations by Kehry, Marilyn, Horlick, Robert, Bowers, Peter, Jun, Toni, da Silva Correia, Jean, Graves, Jonathan, Wang, Yan, Laken, Haley, King, David J.

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