EZH2 mutations at diagnosis in follicular lymphoma: a promising biomarker to guide frontline treatment by Martínez-Laperche, C, Sanz-Villanueva, L, Díaz Crespo, F. J, Muéiz, P, Martín Rojas, R, Carbonell, D, Chicano, M, Suárez-González, J, Menárguez, J, Kwon, M, Diez Martín, J. L, Buéo, I, Bastos Oreiro, M

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Correction: EZH2 mutations at diagnosis in follicular lymphoma: a promising biomarker to guide frontline treatment by Martínez-Laperche, C, Sanz-Villanueva, L, Díaz Crespo, F J, Muñiz, P, Martín Rojas, R, Carbonell, D, Chicano, M, Suárez-González, J, Menárguez, J, Kwon, M, Diez Martín, J L, Buño, I, Bastos Oreiro, M

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Personalized monitoring of circulating tumor DNA by a specific signature of trackable mutations after chimeric antigen receptor t‐cell therapy in non‐Hodgkin B cell lymphoma by Bastos, M., Barrio, S., Martin‐Muñoz, A., iglesia, I., Muñiz, P., Dorado, S., Bailen, R., Poza, M., Chicano, M., Garcia‐Ortiz, A., Diaz‐Crespo, F., Maria, S. Jose, Revilla, E., Valeri, A., Kwon, M., Martínez‐López, J., Buño, I., Martinez‐Laperche, C., Jimenez‐Ubieto, A.

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A VALIDATION, WITH NEW CLINICAL APPLICABILITY, OF A CLINICAL‐GENETIC RISK MODEL THAT PREDICTS THROMBOSIS WITH HIGH SENSITIVITY IN PATIENTS WITH LYMPHOMA by Bastos‐Oreiro, M., Ortiz, J., Pradillo, V., Martinez‐Laperche, C., Salas, E., Buño Borde, I., Díez‐Martín, J., Soria, J., Pascual, C.

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39 Phytochemical indole-3-carbinol synergizes strongly with fludarabine and induces p53-dependent and -independent cell death in chronic lymphocytic leukemia cells irrespective of... by Perez-Chacon, G, Martinez-Laperche, C, Rebolleda, N, Somovilla-Crespo, B, Muñoz-Calleja, C, Buño, I, Zapata, J.M

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P1427: MONITORING CAR‐T CELL IN B‐CELL LYMPHOMA PATIENTS THROUGH SINGLE CHAIN VARIABLE FRAGMENT BY DIGITAL PCR by De La Iglesia San Sebastián, I., Carbonell, D., Pérez Corral, A., Bastos, M., Bailén, R., Silvia, M., Chicano, M., Muñíz, P., Oarbeascoa, G., Anguita, J., Kwon, M., Díez‐Martín, J. L., Buño, I., Martínez‐Laperche, C.

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P391: FLT3‐ITD MEASUREMENT AT DIAGNOSIS AND FOR THE ASSESSMENT OF MINIMAL RESIDUAL DISEASE AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN PATIENTS WITH ACUTE MYELOID L... by Carbonell, D., Chicano, M., Cardero‐Illán, A., Rodriguez‐Macías, G., Muñiz, P., Bailén, R., Oarbeascoa, G., Gómez‐Centurión, I., Anguita, J., Kwon, M., Díez‐Martín, J. L., Buño, I., Martínez‐Laperche, C.

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PB2161: CHARACTERISTICS OF AGGRESSIVE B‐CELL LYMPHOMAS WITH MYC REARRANGEMENT by Ortuzar Pasalodos, A., Chicano, M., Díaz‐Crespo, F., Muñiz, P., Martín‐Rojas, R. M., Gómez‐Centurión, I., Menarguez, J., Kwon, M., Diez‐Martín, J. L., Buño, I., Martínez‐Laperche, C., Bastos‐Oreiro, M.

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P1423: CIRCULATING CELL‐FREE DNA KINETICS MEASURED BY DIGITAL PCR IN LYMPHOMA PATIENTS UNDERGOING CD19‐CAR‐T THERAPY by López‐Esteban, M., Carbonell, D., Bastos‐Oreiro, M., Iglesia, I., Pérez‐Corral, A., Chicano, M., Muñiz, P., Sanz‐Villanueva, L., Bailén, R., Oarbeascoa, G., Anguita, J., Kwon, M., Díez‐Martín, J. L., Buño, I., Martínez‐Laperche, C.

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S1640 POLYMORPHISMS IN CYTOKINES, CHEMOKINES AND THEIR RECEPTORS GENES CONTRIBUTED TO CYTOMEGALOVIRUS REACTIVATION AFTER ALLOGENEIC STEM CELL TRANSPLANTATION by Vallejo, M., Muñiz, P., Carbonell, D., Kwon, M., Solán, L., Chicano, M., Bailén, R., Dorado, N., Díez‐Martín, J.L., Soria, E., Ramírez, N., Martinez‐Laperche, C., Buño, I.

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Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL by Pavlova, Sarka, Malcikova, Jitka, Radova, Lenka, Bonfiglio, Silvia, Cowland, Jack B., Brieghel, Christian, Andersen, Mette Klarskov, Karypidou, Maria, Biderman, Bella V, Doubek, Michael, Lazarian, Gregory, Rapado, Inmaculada, Vynck, Matthijs, Porret, Naomi, Andres, Martin, Rosenberg, Dina, Sahar, Dvora, Martinez-Laperche, Carolina, Borde, Ismael Buño, Hindley, Andrew, Sánchez, Julio Bravo, García-Marco, José, Serrano, Alicia, Ferrer Lores, Blanca, Fernández-Rodriguez, Concepción, Bellosillo, Beatriz, Stilgenbauer, Stephan, Tausch, Eugen, Nikdin, Hero, Quinn, Fiona, Atkinson, Emer, Van De Corput, Lisette, Yildiz, Cafer, Bilbao, Cristina, Florido, Yanira, Thiede, Christian, Schuster, Caroline, Stoj, Anastazja, Czekalska, Sylwia, Chatzidimitriou, Anastasia, Laidou, Stamatia, Bidet, Audrey, Dussiau, Charles, Nollet, Friedel, Piras, Giovanna, Borosova, Tereza, Kurucova, Terezia, Monne, Maria, Smirnova, Svetlana, Nikitin, Evgeny, Sloma, Ivan, Delfau, Marie-Helene, Largeaud, Laetitia, Ysebaert, Loic, Valk, Peter J. M., Christian, Amy, Walewska, Renata, Sebastião, Marta, da Silva, Maria Gomes, Galieni, Piero, Angelini, Mario, Rossi, Davide, Spina, Valeria, Matos, Sónia, Martins, Vânia, Donaldson, David, Stoklosa, Tomasz, Pepek, Monika, Baliakas, Panagiotis, Andreu, Rafa, Luna, Irene, Kahre, Tiina, Murumets, Ülle, Laird, Sophie, Ward, Daniel, Alcoceba, Miguel, Balanzategui, Ana, Scarfo, Lydia, Gandini, Francesca, Zapparoli, Ettore, Blanco, Adoracion, Costa, Pau Abrisqueta, Rodriguez, Ana E., Benito Sanchez, Maria Rocio, Davi, Frédéric, Bravetti, Clothilde, Gameiro, Paula, Martinez-Lopez, Joaquin, Tazon, Barbara, Baran-Marszak, Fanny, Davies, Zadie, Caterwood, Mark, Sudarikov, Andrey B, Rosenquist, Richard, Niemann, Carsten Utoft, Stamatopoulos, Kostas, Ghia, Paolo, Pospisilova, Sarka

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RELAPSE CHARACTERIZATION IN DIFFUSE LARGE B CELL LYMPHOMA PATIENTS UNDERGOING COMMERCIAL CAR‐T CELL THERAPY: EXPERIENCE FROM A SINGLE CENTRE by Bastos‐Oreiro, M., Bailén, R., Silva, P., Monsalvo, S., Pérez Corral, A., Carbonell, D., Díaz Crespo, F., Gómez‐Fernández, I., Oarbeascoa, G., Dorado, N., Muñoz, C., Sabell, S., Menarguez, J., Martínez‐Laperche, C., Buño, I., Anguita Velasco, J., Díez‐Martín, J. L., Kwon, M.

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Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations by Blanco, Gonzalo, Puiggros, Anna, Baliakas, Panagiotis, Athanasiadou, Anastasia, García-Malo, MªDolores, Collado, Rosa, Xochelli, Aliki, Rodríguez-Rivera, María, Ortega, Margarita, Calasanz, Mª José, Luño, Elisa, Vargas, MªTeresa, Grau, Javier, Martínez-Laperche, Carolina, Valiente, Alberto, Cervera, José, Anagnostopoulos, Achilles, Gimeno, Eva, Abella, Eugènia, Stalika, Evangelia, Hernández-Rivas, Jesús Mª, Ortuño, Francisco José, Robles, Diego, Ferrer, Ana, Ivars, David, González, Marcos, Bosch, Francesc, Abrisqueta, Pau, Stamatopoulos, Kostas, Espinet, Blanca

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181 - SF3B1 Mutation in Low-Risk MDS: Impact of its Incorporation to the Updated 2016 Who Classification and Relationship with Ferric Overload by Velao, S. Redondo, Laperche, C. Martinez, Suarez, J., Chicano, M., Ferrnandez, N., Carbonell, D., Buno, I., Diez-martin, J.L., Lopez, P. Font

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ANALYSIS OF EZH2 MUTATIONS IN SOLID AND LIQUID BIOPSY AND ITS ROLE AS PREDICTIVE BIOMARKER FOR CHEMOTHERAPY IN PATIENTS WITH FOLLICULAR LYMPHOMA by Sanz‐Villanueva, L., Díaz Crespo, F., Martín Rojas, R., Carbonell, D., Chicano, M., Suárez‐González, J., Muñiz, P., Menárguez, J., Kwon, M., Diez Martín, J. L., Buño, I., Martínez‐Laperche, C., Bastos Oreiro, M.

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SF3B1 Mutation in Low-Risk MDS: Impact of its Incorporation to the Updated 2016 Who Classification and Relationship with Ferric Overload by Velao, S. Redondo, Laperche, C. Martinez, Suarez, J, Chicano, M, Ferrnandez, N, Carbonell, D, Buno, I, Diez-martin, J.L, Lopez, P. Font

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The Genotype of the Donor for the Polymorphism A7488G of the IL-17 Gene Influences relapse and survival After HLA-Identical Related Stem Cell Transplantation by Martínez-Laperche, C., Noriega, V., Herraiz, Adela, Bosh, A., Guillem, V., Nieto, Jose B, González, M., De La Camara, Rafael, Brunet, S., Jimenez-Velasco, A., Espigado, Ildefonso, Llamas, Juan Carlos Vallejo, Sampol, Antonia, Serrano, David, Gayoso, Jorge, Balsalobre, Pascual, Solano, Carlos, Gallardo, David, Diez-Martín, Jose Luis

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PB1826 COMPOSITE LYMPHOMA CONTAINING MANTLE CELL AND PERIPHERAL T‐CELL LYMPHOMA, NOT OTHERWISE SPECIFIED: A REPORT OF 2 CASES TREATED WITH UP‐FRONT AUTOLOGOUS STEM CELL TRANSPLANTA... by González‐Gascón Y Marín, I., Menarguez, J., Kwon, M., Burdaspal, A., Martinez‐Laperche, C., Castro, Y., Infante, M.S., Diez‐Martín, J.L., Hernández Rivas, J.A.

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Chromosome 8 Abnormalities Are Associated With An Even Worse Outcome And Karyotype Complexity In Patients With Chronic Lymphocytic Leukemia And Tp53 Aberrations by Blanco, G., Puiggros, A., Baliakas, Panagiotis, Athanasiadou, A., Garcia-Malo, M. D., Collado, R., Xochelli, A., Rodriguez-Rivera, M., Ortega, M., Calasanz, M. J., Luno, E., Vargas, M. T., Grau, J., Martinez-Laperche, C., Valiente, A., Papaioannou, G., Cervera, J., Anagnostopoulos, A., Pinan, M. A., Stalika, E., Hernandez-Rivas, J. M., Batlle, A., Salido, M., Ortuno, F., Melero, C., Robles, D., Ferrer, A., Ivars, D., Rodriguez, A., Gonzalez, M., Bosch, F., Abrisqueta, P., Stamatopoulos, K., Espinet, B.

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The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect af... by Noriega, Víctor, Martínez-Laperche, Carolina, Buces, Elena, Pion, Marjorie, Sánchez-Hernández, Noemí, Martín-Antonio, Beatriz, Guillem, Vicent, Bosch-Vizcaya, Anna, Bento, Leyre, González-Rivera, Milagros, Balsalobre, Pascual, Kwon, Mi, Serrano, David, Gayoso, Jorge, de la Cámara, Rafael, Brunet, Salut, Rojas-Contreras, Rafael, Nieto, José B, Martínez, Carmen, Gónzalez, Marcos, Espigado, Ildefonso, Vallejo, Juan C, Sampol, Antonia, Jiménez-Velasco, Antonio, Urbano-Ispizua, Alvaro, Solano, Carlos, Gallardo, David, Díez-Martín, José L, Buño, Ismael

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