Spatial and temporal diversity in genomic instability processes defines lung cancer evolution by de Bruin, Elza C., McGranahan, Nicholas, Mitter, Richard, Salm, Max, Wedge, David C., Yates, Lucy, Jamal-Hanjani, Mariam, Shafi, Seema, Murugaesu, Nirupa, Rowan, Andrew J., Grönroos, Eva, Muhammad, Madiha A., Horswell, Stuart, Gerlinger, Marco, Varela, Ignacio, Jones, David, Marshall, John, Voet, Thierry, Van Loo, Peter, Rassl, Doris M., Rintoul, Robert C., Janes, Sam M., Lee, Siow-Ming, Forster, Martin, Ahmad, Tanya, Lawrence, David, Falzon, Mary, Capitanio, Arrigo, Harkins, Timothy T., Lee, Clarence C., Tom, Warren, Teefe, Enock, Chen, Shann-Ching, Begum, Sharmin, Rabinowitz, Adam, Phillimore, Benjamin, Spencer-Dene, Bradley, Stamp, Gordon, Szallasi, Zoltan, Matthews, Nik, Stewart, Aengus, Campbell, Peter, Swanton, Charles

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Cost-effectiveness of first-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy by Khan, Iftekhar, Morris, Stephen, Hackshaw, Allan, Lee, Siow-Ming

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First-line atezolizumab monotherapy versus single-agent chemotherapy in patients with non-small-cell lung cancer ineligible for treatment with a platinum-containing regimen (IPSOS)... by Lee, Siow Ming, Schulz, Christian, Prabhash, Kumar, Kowalski, Dariusz, Szczesna, Aleksandra, Han, Baohui, Rittmeyer, Achim, Talbot, Toby, Vicente, David, Califano, Raffaele, Cortinovis, Diego, Le, Anh Tuan, Huang, Dingzhi, Liu, Geoffrey, Cappuzzo, Federico, Reyes Contreras, Jessica, Reck, Martin, Palmero, Ramon, Mak, Milena Perez, Hu, Youyou, Morris, Stefanie, Höglander, Elen, Connors, Mary, Biggane, Alice M, Vollan, Hans Kristian, Peters, Solange

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Impact of EGFR Inhibitor in Non―Small Cell Lung Cancer on Progression-Free and Overall Survival: A Meta-Analysis by CHEE KHOON LEE, BROWN, Chris, JEMELA ANNE OSORIO SANCHEZ, VU VAN VU, JOSEPH SIU KIE AU, INOUE, Akira, SIOW MING LEE, GEBSKI, Val, YANG, James Chih-Hsin, GRALLA, Richard J, HIRSH, Vera, THONGPRASERT, Sumitra, TSAI, Chun-Ming, ENG HUAT TAN, HO, James Chung-Man, DATONG CHU, ZAATAR, Adel

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Randomized Trial of Erlotinib Plus Whole-Brain Radiotherapy for NSCLC Patients With Multiple Brain Metastases by SIOW MING LEE, LEWANSKI, Conrad R, COUNSELL, Nicholas, OTTENSMEIER, Christian, BATES, Andrew, PATEL, Nirali, WADSWORTH, Christina, YENTING NGAI, HACKSHAW, Allan, FAIVRE-FINN, Corinne

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A declining CD4 count and diagnosis of HIV-associated Hodgkin lymphoma: do prior clinical symptoms and laboratory abnormalities aid diagnosis? by Gupta, Ravindra K, Marks, Michael, Edwards, Simon G, Smith, Katie, Fletcher, Katie, Lee, Siow-Ming, Ramsay, Alan, Copas, Andrew J, Miller, Robert F

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Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study by Lee, Lennard Y W, Starkey, Thomas, Ionescu, Maria C, Little, Martin, Tilby, Michael, Tripathy, Arvind R, Mckenzie, Hayley S, Al-Hajji, Youssra, Barnard, Matthew, Benny, Liza, Burnett, Alexander, Cattell, Emma L, Charman, Jackie, Clark, James J, Khan, Sam, Ghafoor, Qamar, Illsley, George, Harper-Wynne, Catherine, Hattersley, Rosie J, Lee, Alvin J X, Leonard, Pauline C, Liu, Justin K H, Kinloch, Emma, Lam, Emily, Murphy, Gillian, Rhodes, Malcolm, Robinson, Kate, Pang, Matthew, Pascoe, Jennifer S, Platt, James R, Potter, Vanessa A, Randle, Amelia, Rigg, Anne S, Robinson, Tim M, Roques, Tom W, Roux, René L, Rozmanowski, Stefan, Tuthill, Mark H, Watts, Isabella, Williams, Sarah, Iveson, Tim, Lee, Siow Ming, Middleton, Gary, Middleton, Mark, Protheroe, Andrew, Fittall, Matthew W, Fowler, Tom, Johnson, Peter

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Optimising fusion detection through sequential DNA and RNA molecular profiling of non-small cell lung cancer by Moore, David A., Benafif, Sarah, Poskitt, Benjamin, Argue, Stephanie, Lee, Siow-Ming, Ahmad, Tanya, Papadatos-Pastos, Dionysis, Jamal-Hanjani, Mariam, Bennett, Philip, Forster, Martin D.

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First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial by Lee, Siow Ming, Prof, Khan, Iftekhar, MSc, Upadhyay, Sunil, MD, Lewanski, Conrad, FRCP, Falk, Stephen, MD, Skailes, Geraldine, FRCR, Marshall, Ernie, MD, Woll, Penella J, Prof, Hatton, Matthew, FRCR, Lal, Rohit, MRCP, Jones, Richard, FRCR, Toy, Elizabeth, FRCR, Chao, David, DPhil, Middleton, Gary, MD, Bulley, Sue, SRN, Ngai, Yenting, BSc, Rudd, Robin, MD, Hackshaw, Allan, Prof, Boshoff, Chris, Prof

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A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP) by Starkey, Thomas, Ionescu, Maria C., Tilby, Michael, Little, Martin, Burke, Emma, Fittall, Matthew W., Khan, Sam, Liu, Justin K. H., Platt, James R., Mew, Rosie, Tripathy, Arvind R., Watts, Isabella, Williams, Sophie Therese, Appanna, Nathan, Al-Hajji, Youssra, Barnard, Matthew, Benny, Liza, Burnett, Alexander, Bytyci, Jola, Cattell, Emma L., Cheng, Vinton, Clark, James J., Eastlake, Leonie, Gerrand, Kate, Ghafoor, Qamar, Grumett, Simon, Harper-Wynne, Catherine, Kahn, Rachel, Lee, Alvin J. X., Lomas, Oliver, Lydon, Anna, Mckenzie, Hayley, Panneerselvam, Hari, Pascoe, Jennifer S., Patel, Grisma, Patel, Vijay, Potter, Vanessa A., Randle, Amelia, Rigg, Anne S., Robinson, Tim M., Roylance, Rebecca, Roques, Tom W., Rozmanowski, Stefan, Roux, René L., Shah, Ketan, Sheehan, Remarez, Sintler, Martin, Swarup, Sanskriti, Taylor, Harriet, Tillett, Tania, Tuthill, Mark, Williams, Sarah, Ying, Yuxin, Beggs, Andrew, Iveson, Tim, Lee, Siow Ming, Middleton, Gary, Middleton, Mark, Protheroe, Andrew, Fowler, Tom, Johnson, Peter, Lee, Lennard Y. W.

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Anti-angiogenic Therapy Using Thalidomide Combined With Chemotherapy in Small Cell Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial by Lee, Siow Ming, Woll, Penella J., Rudd, Robin, Ferry, David, O'Brien, Mary, Middleton, Gary, Spiro, Stephen, James, Lindsay, Ali, Kulsam, Jitlal, Mark, Hackshaw, Allan

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Entrectinib-Induced Myocarditis and Acute Heart Failure Responding to Steroid Treatment: A Case Report by Majeed, Mehraab N., Venkatesan, Subramanian, Papadatos-Pastos, Dionysis, Ahmad, Tanya, Forster, Martin, Demetriades, Polyvios, Hughes, Daniel Johnathan, Benafif, Sarah, Lee, Siow Ming

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STAT3 cyclic oligonucleotide decoy—a new therapeutic avenue for NSCLC? by Lee, Lennard Y. W., Mohammad, Summaya, Starkey, Thomas, Lee, Siow-Ming

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Neoantigen-directed immune escape in lung cancer evolution by Rosenthal, Rachel, Cadieux, Elizabeth Larose, Salgado, Roberto, Bakir, Maise Al, Moore, David A., Hiley, Crispin T., Lund, Tom, Tanić, Miljana, Reading, James L., Joshi, Kroopa, Henry, Jake Y., Ghorani, Ehsan, Wilson, Gareth A., Birkbak, Nicolai J., Jamal-Hanjani, Mariam, Veeriah, Selvaraju, Szallasi, Zoltan, Loi, Sherene, Hellmann, Matthew D., Feber, Andrew, Chain, Benny, Herrero, Javier, Quezada, Sergio A., Demeulemeester, Jonas, Van Loo, Peter, Beck, Stephan, McGranahan, Nicholas, Swanton, Charles

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Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution by Hiley, Crispin T., Wilson, Gareth A., Birkbak, Nicolai J., Veeriah, Selvaraju, Herrero, Javier, Swanton, Charles, Swanton, Charles, Czyzewska-Khan, Justyna, Gorman, Pat, Wilson, Gareth, Watkins, Thomas B.K., McGranahan, Nicholas, Mitter, Richard, Escudero, Mickael, Rowan, Andrew, Xu, Hang, Turajlic, Samra, Stone, Richard Kevin, Denner, Tamara, Costa, Marta, Phillimore, Ben, Joshi, Kroopa, Furness, Andrew, Ben Aissa, Assma, Wong, Yien Ning Sophia, Quezada, Sergio, Hartley, John A., Lowe, Helen L., Herrero, Javier, Lawrence, David, Falzon, Mary, Borg, Elaine, Marafioti, Teresa, Janes, Sam M., Thakrar, Ricky, Papadatos-Pastos, Dionysis, Choudhary, Junaid, Califano, Raffaele, Taylor, Paul, Crosbie, Phil, Moss, Stuart, Idries, Faiza, Bishop, Paul, Chaturved, Anshuman, Quinn, Anne Marie, Doran, Helen, Leek, Angela, Blackhall, Fiona, Chemi, Francesca, Gulati, Sakshi, Naidu, Babu, Trotter, Simon, Bellamy, Mary, Bancroft, Hollie, Middleton, Gary, Shaw, Jacqui A., Le Quesne, John, Rathinam, Sridhar, Monteiro, William, Marshall, Hilary, Riley, Joan, Primrose, Lindsay, Anand, Girija, Nicolson, Marianne, Palmer, Shirley, Buchan, Keith, Chetty, Mahendran, Edwards, Alison, Morgan, Fiona, Davies, Helen, Verjee, Azmina, MacKenzie, Mairead, Hackshaw, Allan, Smith, Sean, Alzetani, Aiman, Shaw, Emily, Rice, Alexandra, Raubenheimer, Hilgardt, Proli, Chiara, Cufari, Maria Elena, Bhayani, Harshil, Bakar, Yusura, Mensah, Natalie, Ambrose, Lyn, Devaraj, Anand, Chavan, Hema, Lau, Kelvin, Sheaff, Michael, Schmid, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-sellers, Melanie, Prakash, Vineet, Horey, Tracey, Hill, Jennifer, Suvarna, Kim, Keerio, Allah Dino, Feeney, Sarah, Asante-Siaw, Julius, Dessimoz, Christophe

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Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution by Abbosh, Christopher, Birkbak, Nicolai J., Wilson, Gareth A., Jamal-Hanjani, Mariam, Constantin, Tudor, Salari, Raheleh, Le Quesne, John, Moore, David A., Veeriah, Selvaraju, Rosenthal, Rachel, Marafioti, Teresa, Kirkizlar, Eser, McGranahan, Nicholas, Ward, Sophia, Martinson, Luke, Riley, Joan, Fraioli, Francesco, Al Bakir, Maise, Grönroos, Eva, Zambrana, Francisco, Endozo, Raymondo, Bi, Wenya Linda, Fennessy, Fiona M., Sponer, Nicole, Johnson, Diana, Laycock, Joanne, Shafi, Seema, Czyzewska-Khan, Justyna, Rowan, Andrew, Chambers, Tim, Matthews, Nik, Hiley, Crispin, Lee, Siow Ming, Forster, Martin D., Ahmad, Tanya, Falzon, Mary, Borg, Elaine, Lawrence, David, Hayward, Martin, Kolvekar, Shyam, Panagiotopoulos, Nikolaos, Janes, Sam M., Thakrar, Ricky, Ahmed, Asia, Blackhall, Fiona, Naik, Ashwini, Ganguly, Apratim, Kareht, Stephanie, Shah, Rajesh, Joseph, Leena, Marie Quinn, Anne, Crosbie, Phil A., Naidu, Babu, Middleton, Gary, Langman, Gerald, Trotter, Simon, Nicolson, Marianne, Remmen, Hardy, Kerr, Keith, Chetty, Mahendran, Gomersall, Lesley, Fennell, Dean A., Nakas, Apostolos, Rathinam, Sridhar, Anand, Girija, Khan, Sajid, Russell, Peter, Ezhil, Veni, Ismail, Babikir, Irvin-Sellers, Melanie, Prakash, Vineet, Lester, Jason F., Kornaszewska, Malgorzata, Attanoos, Richard, Adams, Haydn, Davies, Helen, Oukrif, Dahmane, Akarca, Ayse U., Hartley, John A., Lowe, Helen L., Lock, Sara, Iles, Natasha, Bell, Harriet, Ngai, Yenting, Elgar, Greg, Szallasi, Zoltan, Schwarz, Roland F., Herrero, Javier, Stewart, Aengus, Quezada, Sergio A., Peggs, Karl S., Van Loo, Peter, Dive, Caroline, Lin, C. Jimmy, Rabinowitz, Matthew, Aerts, Hugo J. W. L., Hackshaw, Allan, Shaw, Jacqui A., Zimmermann, Bernhard G., Swanton, Charles

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Antibodies against endogenous retroviruses promote lung cancer immunotherapy by Ng, Kevin W., Boumelha, Jesse, Enfield, Katey S. S., Almagro, Jorge, Cha, Hongui, Pich, Oriol, Karasaki, Takahiro, Moore, David A., Salgado, Roberto, Sivakumar, Monica, Young, George, Molina-Arcas, Miriam, de Carné Trécesson, Sophie, Anastasiou, Panayiotis, Fendler, Annika, Au, Lewis, Shepherd, Scott T. C., Martínez-Ruiz, Carlos, Puttick, Clare, Black, James R. M., Watkins, Thomas B. K., Kim, Hyemin, Shim, Seohee, Faulkner, Nikhil, Attig, Jan, Veeriah, Selvaraju, Magno, Neil, Ward, Sophia, Frankell, Alexander M., Al Bakir, Maise, Lim, Emilia L., Hill, Mark S., Wilson, Gareth A., Cook, Daniel E., Birkbak, Nicolai J., Behrens, Axel, Yousaf, Nadia, Popat, Sanjay, Hackshaw, Allan, Hiley, Crispin T., Litchfield, Kevin, McGranahan, Nicholas, Jamal-Hanjani, Mariam, Larkin, James, Lee, Se-Hoon, Turajlic, Samra, Swanton, Charles, Downward, Julian, Kassiotis, George

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Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma by Au, Lewis, Hatipoglu, Emine, Litchfield, Kevin, Beattie, Gordon, Horswell, Stuart, Nicol, David, Mason, Robert, Del Rosario, Lyra, Edmonds, Kim, Lingard, Karla, Sarker, Sarah, Carlyle, Eleanor, Attig, Jan, Becker, Pablo D., Puccio, Ignazio, Lund, Tom, Ghorani, Ehsan, Xu, Hang, Mitchison, Miriam, Moore, David A., Proctor, Ian, Falzon, Mary, Furness, Andrew J.S., Reading, James L., Marafioti, Teresa, Abbosh, Chris, Bridgewater, John, Hochhauser, Daniel, Forster, Martin, Enfield, Katey, Huebner, Ariana, Enver, Tariq, Sinclair, Ron, Rhodes, Zoe, Moore, David, Khiroya, Reena, Ellery, Peter, Veeriah, Selvaraju, Shaw, Heather, Attard, Gert, Akther, Mita Afroza, Naceur-Lombardelli, Cristina, Manzano, Lizi, Summan, Simranpreet, Kanu, Nnenna, Ward, Sophie, Stone, Paddy, Stirling, Caroline, Spain, Lavinia, Shum, Ben, Carlyle, Eleanor, Korteweg, Justine, Chandra, Ashish, Stewart, Ruby, Iredale, Lara-Rose, Enting, Debra, Ghosh, Sharmistha, Karapagniotou, Lena, Pintus, Elias, Tutt, Andrew, Howlett, Sarah, Michalarea, Vasiliki, Caldas, Carlos, Fitzgerald, Rebecca, Provenzano, Elena, Cluroe, Alison, McDermott, Ultan, Tavare, Simon, Roxburgh, Patricia, Chalmers, Anthony, Fraser, Sioban, Oien, Karin, Krebs, Matt, Blackhall, Fiona, Dransfield, Jo, Le Quesne, John, Tanchel, Bruce, Langman, Gerald, Robinson, Andrew, Kerr, Amy, Middleton, Gary, Webb, Joanne, Ottensmeier, Christian, Harrison, David, Hackshaw, Allan, Ledermann, Jonathan, Sharp, Abby, Farrelly, Laura, Bridger, Hayley, Kassiotis, George, Chain, Benny, Larkin, James, Swanton, Charles, Quezada, Sergio A., Turajlic, Samra, Drake, William, Fernando, Archana, Hazell, Steve, Hill, Peter, O'Brien, Tim

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Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors by Lesko, Marta H., Miranda Rota, Enrique, Dahan, Rony, Georgiou, Andrew, Sledzinska, Anna, Werner Sunderland, Mariana, Nicol, David, Beers, Stephen A., Wotherspoon, Andrew, Hayes, Andrew, Stares, Mark, Pickering, Lisa, Rudman, Sarah, Veeriah, Selvaraju, Shafi, Seema, Laycock, Joanne, Bosshard-Carter, Leticia, Goh, Gerald, Rosenthal, Rachel, Hynds, Robert E., Birkbak, Nicolai J., McGranahan, Nicholas, Mitter, Richard, Stewart, Aengus, Rowan, Andrew, Turajlic, Samra, Abbosh, Christopher, Goldman, Jacki, Denner, Tamara, Ward, Sophia, Costa, Marta, Lowe, Helen L., Lawrence, David, Kolvekar, Shyam, Falzon, Mary, Simeon, Celia, Hector, Gemma, Novelli, Marco, Forster, Martin, Papadatos-Pastos, Dionysis, Carnell, Dawn, Navani, Neal, Ahmed, Asia, Taylor, Magali, Choudhary, Junaid, Taylor, Paul, Rammohan, Kendadai, Fontaine, Eustace, Booton, Richard, Moss, Stuart, Idries, Faiza, Joseph, Leena, Moore, Katrina, Waddington, Rachael, Novasio, Juliette, Blackhall, Fiona, Rogan, Jane, Tugwood, Jonathan, Rothwell, Dominic G., Pierce, Jackie, Gulati, Sakshi, Kerr, Amy, Webb, Joanne, Moore, David, Monteiro, William, Marshall, Hilary, Nelson, Louise, Amadi, Anita, Remmen, Hardy, Miller, Joy, Morgan, Fiona, Kornaszewska, Malgorzata, Bell, Harriet, Smith, Sean, Johnson, Benjamin, Lim, Eric, Barbosa, Monica Tavares, Bowman, Alex, Ronquillo, John Carlo, Bhayani, Harshil, Hamilton, Morag, Bakar, Yusura, Mensah, Natalie, Buderi, Silviu, Finch, Jonathan, Green, Sophie, Nicholson, Andrew G., Lau, Kelvin, Schmid, Peter, Conibear, John, Ezhil, Veni, Ismail, Babikir, Prakash, Vineet, Horey, Tracey, Swanton, Charles, Chester, Kerry A., Ravetch, Jeffrey V., Marafioti, Teresa, Peggs, Karl S., Quezada, Sergio A.

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A potential new enriching trial design for selecting non‐small‐cell lung cancer patients with no predictive biomarker for trials based on both histology and early tumor response: f... by Lee, Siow Ming, Hackshaw, Allan

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