Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo by Rafiq, Sarwish, Yeku, Oladapo O, Jackson, Hollie J, Purdon, Terence J, van Leeuwen, Dayenne G, Drakes, Dylan J, Song, Mei, Miele, Matthew M, Li, Zhuoning, Wang, Pei, Yan, Su, Xiang, Jingyi, Ma, Xiaojing, Seshan, Venkatraman E, Hendrickson, Ronald C, Liu, Cheng, Brentjens, Renier J

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CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response by Kuhn, Nicholas F., Purdon, Terence J., van Leeuwen, Dayenne G., Lopez, Andrea V., Curran, Kevin J., Daniyan, Anthony F., Brentjens, Renier J.

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Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System by Avanzi, Mauro P., Yeku, Oladapo, Li, Xinghuo, Wijewarnasuriya, Dinali P., van Leeuwen, Dayenne G., Cheung, Kenneth, Park, Hyebin, Purdon, Terence J., Daniyan, Anthony F., Spitzer, Matthew H., Brentjens, Renier J.

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Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression by Curran, Kevin J, Seinstra, Beatrijs A, Nikhamin, Yan, Yeh, Raymond, Usachenko, Yelena, van Leeuwen, Dayenne G, Purdon, Terence, Pegram, Hollie J, Brentjens, Renier J

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Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies by Watanabe, Norihiro, Mo, Feiyan, Zheng, Rong, Ma, Royce, Bray, Vanesa C., van Leeuwen, Dayenne G., Sritabal-Ramirez, Juntima, Hu, Hongxiang, Wang, Sha, Mehta, Birju, Srinivasan, Madhuwanti, Scherer, Lauren D., Zhang, Huimin, Thakkar, Sachin G., Hill, LaQuisa C., Heslop, Helen E., Cheng, Chonghui, Brenner, Malcolm K., Mamonkin, Maksim

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Safety and tolerability of conditioning chemotherapy followed by CD19-targeted CAR T cells for relapsed/refractory CLL by Geyer, Mark B, Rivière, Isabelle, Sénéchal, Brigitte, Wang, Xiuyan, Wang, Yongzeng, Purdon, Terence J, Hsu, Meier, Devlin, Sean M, Palomba, M Lia, Halton, Elizabeth, Bernal, Yvette, van Leeuwen, Dayenne G, Sadelain, Michel, Park, Jae H, Brentjens, Renier J

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Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity by Ma, Royce, Woods, Mae, Burkhardt, Phillip, Crooks, Noah, van Leeuwen, Dayenne G., Shmidt, Daniil, Couturier, Jacob, Chaumette, Alexandre, Popat, Divya, Hill, LaQuisa C., Rouce, Rayne H., Thakkar, Sachin, Orozco, Aaron F., Carisey, Alexandre F., Brenner, Malcolm K., Mamonkin, Maksim

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Abstract 2568: CAR T cells secreting an immune checkpoint blockade scFv have enhanced anti-tumor efficacy by Rafiq, Sarwish, Yeku, Oladapo, Jackson, Hollie, purdon, Terence, Leeuwen, Dayenne van, Yan, Su, Wang, Pei, Xiang, Jingyi, Liu, Cheng, Seshan, Venkatraman, Brentjens, Renier

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IL-18 Secreting CAR T Cells Enhance Cell Persistence, Induce Prolonged B Cell Aplasia and Eradicate CD19+ Tumor Cells without Need for Prior Conditioning by Avanzi, Mauro P., G. van Leeuwen, Dayenne, Li, Xinghuo, Cheung, Kenneth, Park, Hyebin, Purdon, Terence J., Brentjens, Renier J.

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Enhancing CAR T Cell Anti-Tumor Efficacy through Secreted Single Chain Variable Fragment (scFv) Immune Checkpoint Blockade by Rafiq, Sarwish, Jackson, Hollie J., Yeku, Oladapo, Purdon, Terence J, van Leeuwen, Dayenne G., Curran, Kevin J., Ahmed, Ryan N, Cullen, Grace D, Yan, Su, Wang, Pei, Xiang, Jingyi, Liu, Cheng, Brentjens, Renier J.

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