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IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy
by
Rubino, Viviana
,
Hüppi, Michelle
,
Höpner, Sabine
,
Tortola, Luigi
,
Schnüriger, Noah
,
Legenne, Hugo
,
Taylor, Lea
,
Voggensperger, Svenja
,
Keller, Irene
,
Bruggman, Remy
,
Kronig, Marie-Noëlle
,
Bacher, Ulrike
,
Kopf, Manfred
,
Ochsenbein, Adrian F.
,
Riether, Carsten
Published in
Cell reports. Medicine
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Cell Reports. Medicine
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Aml
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Animals
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Cd4-Positive T-Lymphocytes - Drug Effects
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Cd4-Positive T-Lymphocytes - Immunology
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Cd4-Positive T-Lymphocytes - Metabolism
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Cd70-Targeting Car T Cells
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Cell Biology
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Cell Differentiation - Drug Effects
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Cell Line, Tumor
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Cytarabine
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Cytarabine - Pharmacology
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Cytarabine - Therapeutic Use
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Female
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Humans
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Il-21
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Immunotherapy, Adoptive - Methods
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Interleukins - Metabolism
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Leukemia Stem Cell
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Leukemia, Myeloid, Acute - Drug Therapy
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Leukemia, Myeloid, Acute - Metabolism
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