Recent advances in methodology for clinical trials in small populations: the InSPiRe project by Friede, Tim, Posch, Martin, Zohar, Sarah, Alberti, Corinne, Benda, Norbert, Comets, Emmanuelle, Day, Simon, Dmitrienko, Alex, Graf, Alexandra, Günhan, Burak Kürsad, Hee, Siew Wan, Lentz, Frederike, Madan, Jason, Miller, Frank, Ondra, Thomas, Pearce, Michael, Röver, Christian, Toumazi, Artemis, Unkel, Steffen, Ursino, Moreno, Wassmer, Gernot, Stallard, Nigel

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Dose‐finding methods for Phase I clinical trials using pharmacokinetics in small populations by Ursino, Moreno, Zohar, Sarah, Lentz, Frederike, Alberti, Corinne, Friede, Tim, Stallard, Nigel, Comets, Emmanuelle

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Evidence generation throughout paediatric medicines life cycle: findings from collaborative work between European Medicines Agency (EMA) and EUnetHTA on use of extrapolation by Karres, Dominik, Pino-Barrio, María José, Benchetrit, Sylvie, Benda, Norbert, Cochat, Pierre, Galluzzo, Sara, García-Solís, Alejandro, Gonzalez, Sara, de Lisa, Roberto, Khan, David, Lankester, Rita, Lentz, Frederike, Martínez-Ortega, Pilar Angustias, Montilla, Simona, Morales, Daniel R, Tshinanu, Flora Musuamba, Sánchez, Sonia Pulido, Montero, Ana Rossignoli, Scherer, Sabine, Thomson, Andrew, Garrido, Belén Torres, Umuhire, Denise, Wang, Siri, Bax, Ralph, Hedberg, Niklas

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A dose finding design for seizure reduction in neonates by Ursino, Moreno, Yuan, Ying, Alberti, Corinne, Comets, Emmanuelle, Favrais, Geraldine, Friede, Tim, Lentz, Frederike, Stallard, Nigel, Zohar, Sarah

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Directions for new developments on statistical design and analysis of small population group trials by Hilgers, Ralf-Dieter, Roes, Kit, Stallard, Nigel

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Commentary on the MID3 Good Practices Paper by Manolis, Efthymios, Brogren, Jacob, Cole, Susan, Hay, Justin L., Nordmark, Anna, Karlsson, Kristin E., Lentz, Frederike, Benda, Norbert, Wangorsch, Gaby, Pons, Gerard, Zhao, Wei, Gigante, Valeria, Serone, Francesca, Standing, Joseph F., Dokoumetzidis, Aris, Vakkilainen, Juha, van den Heuvel, Michiel, Mangas Sanjuan, Victor, Taminiau, Johannes, Kerwash, Essam, Khan, David, Musuamba, Flora Tshinanu, Skottheim Rusten, Ine

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Approaches to sample size calculation for clinical trials in rare diseases by Friede, Tim, Alberti, Corinne, Benda, Norbert, Comets, Emmanuelle, Dmitrienko, Alex, Graf, Alexandra, Günhan, Burak Kürsad, Lentz, Frederike, Ondra, Thomas, Röver, Christian, Toumazi, Artemis, Unkel, Steffen, Ursino, Moreno, Wassmer, Gernot, Miller, Frank, Zohar, Sarah, Stallard, Nigel, Madan, Jason, Posch, Martin, Hee, Siew Wan, Pearce, Michael, Vågerö, Mårten, Day, Simon

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