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Bis-aryl-α,β-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol
by
Chitre, Siddhi
,
Ray, Anne-Marie
,
Stevens, Mckayla
,
Doud, Emma H
,
Liechty, Hope
,
Washburn, Alex
,
Tepper, Katelyn
,
Sivinski, Jared
,
O'Hagan, Heather M
,
Georgiadis, Millie M
,
Chapman, Eli
,
Johnson, Steven M
Published in
Bioorganic & medicinal chemistry
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Discovery of a Tunable Heterocyclic Electrophile 4‑Chloro-pyrazolopyridine That Defines a Unique Subset of Ligandable Cysteines
by
Kim, Hong-Rae
,
Byun, David P.
,
Thakur, Kalyani
,
Ritchie, Jennifer
,
Xie, Yixin
,
Holewinski, Ronald
,
Suazo, Kiall F.
,
Stevens, Mckayla
,
Liechty, Hope
,
Tagirasa, Ravichandra
,
Jing, Yihang
,
Andresson, Thorkell
,
Johnson, Steven M.
,
Yoo, Euna
Published in
ACS chemical biology
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Acs Chemical Biology
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Bioorganic & Medicinal Chemistry
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Biochemistry & Molecular Biology
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Humans
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Life Sciences & Biomedicine
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Science & Technology
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Chaperonin
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Chaperonin 10 - Metabolism
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Chaperonin 60 - Metabolism
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Chaperonins
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Chemistry
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Chemistry, Medicinal
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Chemistry, Organic
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Chemotherapeutics
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Colorectal Cancer
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Colorectal Neoplasms - Drug Therapy
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Colorectal Neoplasms - Metabolism
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Cysteine - Chemistry
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Cytosol - Metabolism
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Drug Discovery
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Hsp10
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Hsp60
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American Chemical Society:jisc Collections:american Chemical Society Read & Publish Agreement 2022-2024 (Reading List)
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Elsevier Sciencedirect Journals
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Sciencedirect Freedom Collection
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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