Search Results - Lightbown, Ian

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  1. 1
    Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes

    Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes by Coker, Susan J, Batey, Andrew J, Lightbown, Ian D, Díaz, Mary E, Eisner, David A

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  2. 2
    Towards automation of a valuable preclinical cardiac safety pharmacology assay: Evaluation of the effects of cardiac ion channel blockers on cardiac repolarisation in vitro

    Towards automation of a valuable preclinical cardiac safety pharmacology assay: Evaluation of the effects of cardiac ion channel blockers on cardiac repolarisation in vitro by Lightbown, Ian D., Johnson, Mark, Davis, Anne, Leaney, Joanne, Leishman, Derek J.

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  3. 3
    Potentiation of halofantrine‐induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine

    Potentiation of halofantrine‐induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine by Lightbown, Ian D, Lambert, James P, Edwards, Geoffrey, Coker, Susan J

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  4. 4
    A cross-species translational pharmacokinetic-pharmacodynamic evaluation of core body temperature reduction by the TRPM8 blocker PF-05105679

    A cross-species translational pharmacokinetic-pharmacodynamic evaluation of core body temperature reduction by the TRPM8 blocker PF-05105679 by Gosset, James R., Beaumont, Kevin, Matsuura, Tomomi, Winchester, Wendy, Attkins, Neil, Glatt, Sophie, Lightbown, Ian, Ulrich, Kristina, Roberts, Sonia, Harris, Jolie, Mesic, Emir, van Steeg, Tamara, Hijdra, Diana, van der Graaf, Piet H.

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  5. 5
    Comparison of the acute cardiotoxicity of the antimalarial drug halofantrine in vitro and in vivo in anaesthetized guinea‐pigs

    Comparison of the acute cardiotoxicity of the antimalarial drug halofantrine in vitro and in vivo in anaesthetized guinea‐pigs by Batey, Andrew J., Lightbown, Ian D., Lambert, James P., Edwards, Geoffrey, Coker, Susan J.

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  6. 6
    Translation between in vitro inhibition of the cardiac Nav1.5 channel and pre-clinical and clinical QRS widening

    Translation between in vitro inhibition of the cardiac Nav1.5 channel and pre-clinical and clinical QRS widening by Cordes, Jason, Li, Cheryl, Dugas, Jeremy, Austin-LaFrance, Robert, Lightbown, Ian, Engwall, Michael, Sutton, Michael, Steidl-Nichols, Jill

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  7. 7
    Book review: 3GS Edition

    Book review: 3GS Edition by Hawkey, Ian

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