Sigma‐2 receptor antagonists rescue neuronal dysfunction induced by Parkinson’s patient brain‐derived α‐synuclein by Limegrover, Colleen S., Yurko, Raymond, Izzo, Nicholas J., LaBarbera, Kelsie M., Rehak, Courtney, Look, Gary, Rishton, Gilbert, Safferstein, Hank, Catalano, Susan M.

Get full text

Alzheimer’s protection effect of A673T mutation may be driven by lower Aβ oligomer binding affinity by Limegrover, Colleen S., LeVine, Harry, Izzo, Nicholas J., Yurko, Raymond, Mozzoni, Kelsie, Rehak, Courtney, Sadlek, Kelsey, Safferstein, Hank, Catalano, Susan M.

Get full text

Discovery of Investigational Drug CT1812, an Antagonist of the Sigma‑2 Receptor Complex for Alzheimer’s Disease by Rishton, Gilbert M, Look, Gary C, Ni, Zhi-Jie, Zhang, Jason, Wang, Yingcai, Huang, Yaodong, Wu, Xiaodong, Izzo, Nicholas J, LaBarbera, Kelsie M, Limegrover, Colleen S, Rehak, Courtney, Yurko, Raymond, Catalano, Susan M

Get full text

Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology by Szebényi, Kornélia, Wenger, Léa M. D., Sun, Yu, Dunn, Alexander W. E., Limegrover, Colleen A., Gibbons, George M., Conci, Elena, Paulsen, Ole, Mierau, Susanna B., Balmus, Gabriel, Lakatos, András

Get full text

Modeling the mature CNS: A predictive screening platform for neurodegenerative disease drug discovery by LaBarbera, Kelsie Mozzoni, Limegrover, Colleen, Rehak, Courtney, Yurko, Raymond, Izzo, Nicholas John, Knezovich, Nicole, Watto, Emily, Waybright, Lora, Catalano, Susan M.

Get full text