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TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets
by
Lin, Gloria H Y
,
Chai, Vien
,
Lee, Vivian
,
Dodge, Karen
,
Truong, Tran
,
Wong, Mark
,
Johnson, Lisa D
,
Linderoth, Emma
,
Pang, Xinli
,
Winston, Jeff
,
Petrova, Penka S
,
Uger, Robert A
,
Viller, Natasja N
Published in
PloS one
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Signal requirement for cortical potential of transplantable human neuroepithelial stem cells
by
Varga, Balazs V.
,
Faiz, Maryam
,
Pivonkova, Helena
,
Khelifi, Gabriel
,
Yang, Huijuan
,
Gao, Shangbang
,
Linderoth, Emma
,
Zhen, Mei
,
Karadottir, Ragnhildur Thora
,
Hussein, Samer M.
,
Nagy, Andras
Published in
Nature communications
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Activated Cdc42-associated Kinase 1 (Ack1) Is Required for Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Receptor Recruitment to Lipid Rafts and Induction of Cell...
by
Linderoth, Emma
,
Pilia, Giulia
,
Mahajan, Nupam P.
,
Ferby, Ingvar
Published in
The Journal of biological chemistry
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TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding
by
Petrova, Penka S
,
Viller, Natasja Nielsen
,
Wong, Mark
,
Pang, Xinli
,
Lin, Gloria H Y
,
Dodge, Karen
,
Chai, Vien
,
Chen, Hui
,
Lee, Vivian
,
House, Violetta
,
Vigo, Noel T
,
Jin, Debbie
,
Mutukura, Tapfuma
,
Charbonneau, Marilyse
,
Truong, Tran
,
Viau, Stephane
,
Johnson, Lisa D
,
Linderoth, Emma
,
Sievers, Eric L
,
Maleki Vareki, Saman
,
Figueredo, Rene
,
Pampillo, Macarena
,
Koropatnick, James
,
Trudel, Suzanne
,
Mbong, Nathan
,
Jin, Liqing
,
Wang, Jean C Y
,
Uger, Robert A
Published in
Clinical cancer research
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Abstract 2720: The CD47-blocking innate immune checkpoint inhibitor, TTI-621, triggers CD47-mediated tumor cell apoptosis
by
Izrailit, Julia Bershadsky
,
Viller, Natasja Nielsen
,
Pang, Xinli
,
Petrova, Penka S.
,
Uger, Robert A.
,
Winston, Jeff
,
Linderoth, Emma
Published in
Cancer research (Chicago, Ill.)
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Mig6 Is a Sensor of EGF Receptor Inactivation that Directly Activates c-Abl to Induce Apoptosis during Epithelial Homeostasis
by
Hopkins, Sarah
,
Linderoth, Emma
,
Hantschel, Oliver
,
Suarez-Henriques, Paula
,
Pilia, Giulia
,
Kendrick, Howard
,
Smalley, Matthew J.
,
Superti-Furga, Giulio
,
Ferby, Ingvar
Published in
Developmental cell
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TTI-621
by
Lin, Gloria H. Y
,
Chai, Vien
,
Lee, Vivian
,
Dodge, Karen
,
Truong, Tran
,
Wong, Mark
,
Johnson, Lisa D
,
Linderoth, Emma
,
Pang, Xinli
,
Winston, Jeff
,
Petrova, Penka S
,
Uger, Robert A
,
Viller, Natasja N
Published in
PloS one
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Abstract 2646: Intratumoral delivery of TTI-621 (SIRPαFc), a CD47-blocking immunotherapeutic, inhibits tumor growth and prolongs animal survival in a subcutaneous B cell lymphoma m...
by
Lin, Gloria H.
,
Charbonneau, Marilyse
,
Chai, Vien
,
O'Connor, Alison M.
,
Bossen, Bolette
,
Chen, Hui
,
Wong, Mark
,
Viller, Natasja N.
,
Linderoth, Emma
,
Johnson, Lisa D.
,
Pang, Xinli
,
Winston, Jeffery
,
Petrova, Penka S.
,
Uger, Robert A.
Published in
Cancer research (Chicago, Ill.)
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Abstract 2653: The anti-myeloma activity of TTI-621 (SIRPαFc), a CD47-blocking immunotherapeutic, is enhanced when combined with a proteasome inhibitor
by
Linderoth, Emma
,
Helke, Simone
,
Lee, Vivian
,
Mutukura, Tapfuma
,
Wong, Mark
,
Lin, Gloria H.
,
Johnson, Lisa D.
,
Pang, Xinli
,
Winston, Jeff
,
Petrova, Penka S.
,
Uger, Robert A.
,
Viller, Natasja N.
Published in
Cancer research (Chicago, Ill.)
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Abstract 2709: TTI-622 (SIRPα-IgG4 Fc), a CD47-blocking innate immune checkpoint inhibitor, suppresses tumor growth and demonstrates enhanced efficacy in combination with antitumor...
by
Lin, Gloria H. Y.
,
Viller, Natasja N.
,
Chabonneau, Marilyse
,
Brinen, Laura
,
Mutukura, Tapfuma
,
Dodge, Karen
,
Helke, Simone
,
Chai, Vien
,
House, Violetta
,
Lee, Vivian
,
Chen, Hui
,
O'Connor, Alison
,
Jin, Debbie
,
Figueredo, Rene
,
Vareki, Saman Maleki
,
Wong, Mark
,
Linderoth, Emma
,
Johnson, Lisa D.
,
Pang, Xinli
,
Koropatnick, James
,
Winston, Jeff
,
Petrova, Penka S.
,
Uger, Robert A.
Published in
Cancer research (Chicago, Ill.)
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Abstract B028: Blockade of the CD47 “Do not eat” signal by TTI-621 (SIRPαFc) leads to enhanced antitumor CD8+ T cell responses in vitro
by
Viller, Natasja Nielsen
,
Truong, Tran
,
Linderoth, Emma
,
Johnson, Lisa D.
,
Viau, Stephane
,
Lin, Gloria H. Y.
,
Wong, Mark
,
Pang, Xinli
,
Petrova, Penka S.
,
Uger, Robert A.
Published in
Cancer immunology research
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Genome-wide signatures of complex introgression and adaptive evolution in the big cats
by
Figueiró, Henrique V
,
Li, Gang
,
Trindade, Fernanda J
,
Assis, Juliana
,
Pais, Fabiano
,
Fernandes, Gabriel
,
Santos, Sarah H D
,
Hughes, Graham M
,
Komissarov, Aleksey
,
Antunes, Agostinho
,
Trinca, Cristine S
,
Rodrigues, Maíra R
,
Linderoth, Tyler
,
Bi, Ke
,
Silveira, Leandro
,
Azevedo, Fernando C C
,
Kantek, Daniel
,
Ramalho, Emiliano
,
Brassaloti, Ricardo A
,
Villela, Priscilla M S
,
Nunes, Adauto L V
,
Teixeira, Rodrigo H F
,
Morato, Ronaldo G
,
Loska, Damian
,
Saragüeta, Patricia
,
Gabaldón, Toni
,
Teeling, Emma C
,
O'Brien, Stephen J
,
Nielsen, Rasmus
,
Coutinho, Luiz L
,
Oliveira, Guilherme
,
Murphy, William J
,
Eizirik, Eduardo
Published in
Science advances
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Proceedings of the 14th annual conference of INEBRIA: New York, NY, USA, September 14–15, 2017
by
Holloway, Aisha S.
,
Ferguson, Jennifer
,
Landale, Sarah
,
Cariola, Laura
,
Newbury-Birch, Dorothy
,
Flynn, Amy
,
Knight, John R.
,
Sherritt, Lon
,
Harris, Sion K.
,
O’Donnell, Amy J.
,
Kaner, Eileen
,
Hanratty, Barbara
,
Loree, Amy M.
,
Yonkers, Kimberly A.
,
Ondersma, Steven J.
,
Gilstead-Hayden, Kate
,
Martino, Steve
,
Adam, Angeline
,
Schwartz, Robert P.
,
Wu, Li-Tzy
,
Subramaniam, Geetha
,
Sharma, Gaurav
,
McNeely, Jennifer
,
Berman, Anne H.
,
Kolaas, Karoline
,
Petersén, Elisabeth
,
Bendtsen, Preben
,
Hedman, Erik
,
Linderoth, Catharina
,
Müssener, Ulrika
,
Sinadinovic, Kristina
,
Spak, Fredrik
,
Gremyr, Ida
,
Thurang, Anna
,
Mitchell, Ann M.
,
Finnell, Deborah
,
Savage, Christine L.
,
Mahmoud, Khadejah F.
,
Riordan, Benjamin C.
,
Conner, Tamlin S.
,
Flett, Jayde A. M.
,
Scarf, Damian
,
McRee, Bonnie
,
Vendetti, Janice
,
Gallucci, Karen Steinberg
,
Robaina, Kate
,
Clark, Brendan J.
,
Jones, Jacqueline
,
Reed, Kathryne D.
,
Hodapp, Rachel M.
,
Douglas, Ivor
,
Burnham, Ellen L.
,
Aagaard, Laura
,
Cook, Paul F.
,
Harris, Brett R.
,
Yu, Jiang
,
Wolff, Margaret
,
Rogers, Meighan
,
Barbosa, Carolina
,
Wedehase, Brendan J.
,
Dunlap, Laura J.
,
Mitchell, Shannon G.
,
Dusek, Kristi A.
,
Gryczynski, Jan
,
Kirk, Arethusa S.
,
Oros, Marla T.
,
Hosler, Colleen
,
O’Grady, Kevin E.
,
Brown, Barry S.
,
Angus, Colin
,
Sherborne, Sidney
,
Gillespie, Duncan
,
Meier, Petra
,
Brennan, Alan
,
de Vargas, Divane
,
Soares, Janaina
,
Castelblanco, Donna
,
Doran, Kelly M.
,
Wittman, Ian
,
Shelley, Donna
,
Rotrosen, John
,
Gelberg, Lillian
,
Edelman, E. Jennifer
,
Maisto, Stephen A.
,
Hansen, Nathan B.
,
Cutter, Christopher J.
,
Deng, Yanhong
,
Dziura, James
,
Fiellin, Lynn E.
,
O’Connor, Patrick G.
,
Bedimo, Roger
,
Gibert, Cynthia
,
Marconi, Vincent C.
,
Rimland, David
,
Rodriguez-Barradas, Maria C.
,
Simberkoff, Michael S.
,
Justice, Amy C.
,
Bryant, Kendall J.
,
Fiellin, David A.
,
Giles, Emma L.
Published in
Addiction science & clinical practice
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Proceedings of the 14th annual conference of INEBRIA
by
Aisha S. Holloway
,
Jennifer Ferguson
,
Sarah Landale
,
Laura Cariola
,
Dorothy Newbury-Birch
,
Amy Flynn
,
John R. Knight
,
Lon Sherritt
,
Sion K. Harris
,
Amy J. O’Donnell
,
Eileen Kaner
,
Barbara Hanratty
,
Amy M. Loree
,
Kimberly A. Yonkers
,
Steven J. Ondersma
,
Kate Gilstead-Hayden
,
Steve Martino
,
Angeline Adam
,
Robert P. Schwartz
,
Li-Tzy Wu
,
Geetha Subramaniam
,
Gaurav Sharma
,
Jennifer McNeely
,
Anne H. Berman
,
Karoline Kolaas
,
Elisabeth Petersén
,
Preben Bendtsen
,
Erik Hedman
,
Catharina Linderoth
,
Ulrika Müssener
,
Kristina Sinadinovic
,
Fredrik Spak
,
Ida Gremyr
,
Anna Thurang
,
Ann M. Mitchell
,
Deborah Finnell
,
Christine L. Savage
,
Khadejah F. Mahmoud
,
Benjamin C. Riordan
,
Tamlin S. Conner
,
Jayde A. M. Flett
,
Damian Scarf
,
Bonnie McRee
,
Janice Vendetti
,
Karen Steinberg Gallucci
,
Kate Robaina
,
Brendan J. Clark
,
Jacqueline Jones
,
Kathryne D. Reed
,
Rachel M. Hodapp
,
Ivor Douglas
,
Ellen L. Burnham
,
Laura Aagaard
,
Paul F. Cook
,
Brett R. Harris
,
Jiang Yu
,
Margaret Wolff
,
Meighan Rogers
,
Carolina Barbosa
,
Brendan J. Wedehase
,
Laura J. Dunlap
,
Shannon G. Mitchell
,
Kristi A. Dusek
,
Jan Gryczynski
,
Arethusa S. Kirk
,
Marla T. Oros
,
Colleen Hosler
,
Kevin E. O’Grady
,
Barry S. Brown
,
Colin Angus
,
Sidney Sherborne
,
Duncan Gillespie
,
Petra Meier
,
Alan Brennan
,
Divane de Vargas
,
Janaina Soares
,
Donna Castelblanco
,
Kelly M. Doran
,
Ian Wittman
,
Donna Shelley
,
John Rotrosen
,
Lillian Gelberg
,
E. Jennifer Edelman
,
Stephen A. Maisto
,
Nathan B. Hansen
,
Christopher J. Cutter
,
Yanhong Deng
,
James Dziura
,
Lynn E. Fiellin
,
Patrick G. O’Connor
,
Roger Bedimo
,
Cynthia Gibert
,
Vincent C. Marconi
,
David Rimland
,
Maria C. Rodriguez-Barradas
,
Michael S. Simberkoff
,
Amy C. Justice
,
Kendall J. Bryant
,
David A. Fiellin
,
Emma L. Giles
Published in
Addiction science & clinical practice
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