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Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch
by
Gretarsson, Kristjan H
,
Abini-Agbomson, Stephen
,
Gloor, Susan L
,
Weinberg, Daniel N
,
McCuiston, Jamie L
,
Kumary, Vishnu Udayakumar Sunitha
,
Hickman, Allison R
,
Sahu, Varun
,
Lee, Rachel
,
Xu, Xinjing
,
Lipieta, Natalie
,
Flashner, Samuel
,
Adeleke, Oluwatobi A
,
Popova, Irina K
,
Taylor, Hailey F
,
Noll, Kelsey
,
Windham, Carolina Lin
,
Maryanski, Danielle N
,
Venters, Bryan J
,
Nakagawa, Hiroshi
,
Keogh, Michael-Christopher
,
Armache, Karim-Jean
,
Lu, Chao
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Science advances
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Science Advances
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Biomedicine And Life Sciences
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Cancer
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Cell Line, Tumor
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Cpg Islands
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Cryoelectron Microscopy
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Dna -Methyltransferases - Genetics
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Dna -Methyltransferases - Metabolism
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Dna Methylation
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Dna Methyltransferase 3A
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Histones - Metabolism
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Humans
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Multidisciplinary Sciences
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Neoplasms - Genetics
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Neoplasms - Metabolism
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Neoplasms - Pathology
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Nucleosomes - Metabolism
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Polycomb-Group Proteins - Genetics
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Polycomb-Group Proteins - Metabolism
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Promoter Regions, Genetic
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Protein Binding
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