Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival by Logsdon, Derek P., Shah, Fenil, Carta, Fabrizio, Supuran, Claudiu T., Kamocka, Malgorzata, Jacobsen, Max H., Sandusky, George E., Kelley, Mark R., Fishel, Melissa L.

Get full text

Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models by Logsdon, Derek P, Grimard, Michelle, Luo, Meihua, Shahda, Safi, Jiang, Yanlin, Tong, Yan, Yu, Zhangsheng, Zyromski, Nicholas, Schipani, Ernestina, Carta, Fabrizio, Supuran, Claudiu T, Korc, Murray, Ivan, Mircea, Kelley, Mark R, Fishel, Melissa L

Get full text

Apurinic/Apyrimidinic Endonuclease/Redox Factor-1 (APE1/Ref-1) Redox Function Negatively Regulates NRF2 by Fishel, Melissa L., Wu, Xue, Devlin, Cecilia M., Logsdon, Derek P., Jiang, Yanlin, Luo, Meihua, He, Ying, Yu, Zhangsheng, Tong, Yan, Lipking, Kelsey P., Maitra, Anirban, Rajeshkumar, N.V., Scandura, Glenda, Kelley, Mark R., Ivan, Mircea

Get full text

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic by Shah, Fenil, Logsdon, Derek, Messmann, Richard A., Fehrenbacher, Jill C., Fishel, Melissa L., Kelley, Mark R.

Get full text

Mutation in erythroid specific transcription factor KLF1 causes Hereditary Spherocytosis in the Nan hemolytic anemia mouse model by Heruth, Daniel P., Hawkins, Troy, Logsdon, Derek P., Gibson, Margaret I., Sokolovsky, Inna V., Nsumu, Ndona N., Major, Stephanie L., Fegley, Barbara, Woods, Gerald M., Lewing, Karen B., Neville, Kathleen A., Cornetta, Kenneth, Peterson, Kenneth R., White, Robert A.

Get full text

Hematologic characterization and chromosomal localization of the novel dominantly inherited mouse hemolytic anemia, neonatal anemia ( Nan) by White, Robert A., Sokolovsky, Inna V., Britt, Margaret I., Nsumu, Ndona N., Logsdon, Derek P., McNulty, Steven G., Wilmes, Leigh A., Brewer, Brandon P., Wirtz, Eric, Joyce, Heather R., Fegley, Barbara, Smith, Ann, Heruth, Daniel P.

Get full text

Research from the bedside to the lab bench & back by White, Robert A, Silvey, Michael, Logsdon, Derek P

Get full text

Abstract 2941: APE1/Ref-1 redox signaling regulates HIF1a-mediated CA9 expression in hypoxic pancreatic cancer cells: Combination treatment in patient-derived pancreatic tumor mode... by Logsdon, Derek, Shah, Fenil, Carta, Fabrizio, Supuran, Claudiu, Fishel, Melissa, Kelley, Mark R.

Get full text

Inhibition of Apurinic/Apyrimidinic Endonuclease I’s Redox Activity Revisited by Zhang, Jun, Luo, Meihua, Marasco, Daniela, Logsdon, Derek, LaFavers, Kaice A, Chen, Qiujia, Reed, April, Kelley, Mark R, Gross, Michael L, Georgiadis, Millie M

Get full text

Abstract B51: Regulation of HIF1α under hypoxia by APE1/Ref-1 impacts CA9 expression: Dual-targeting in patient-derived 3D pancreatic cancer models by Logsdon, Derek P., Grimard, Michelle, Shahda, Safi, Zyromski, Nicholas, Schipani, Ernestina, Carta, Fabrizio, Supuran, Claudiu T., Korc, Murray, Ivan, Mircea, Kelley, Mark R., Fishel, Melissa L.

Get full text

Abstract 4740: Targeting Ref-1/APE1 pathway inhibition in pancreatic cancer using APX3330 for clinical trials by Fishel, Melissa L., Logsdon, Derek P., Grimard, Michelle L., Supuran, Claudiu T., Zyromski, Nicholas, Ivan, Mircea, Kelley, Mark R., Shah, Fenil

Get full text

Abstract B158: Targeting APE1/Ref-1 results in inhibition of hypoxia signaling genes by Logsdon, Derek P., Cheng, Huiwen, Luo, Meihua, Shahda, Safi, Hao, Yangyang, Tong, Yan, Yu, Zhangsheng, Zyromski, Nicholas, Schipani, Ernestina, Liu, Yunlong, Supuran, Claudiu T., Ivan, Mircea, Kelley, Mark R., Fishel, Melissa L.

Get full text

Identification of a novel transcription factor impacting iron homeostasis by Miller, Kyle Lamar, Theisen, Christopher, Cone, Brian, Williams, John, Logsdon, Derek P, Costa, Flavia C, White, Robert A

Get full text

The Xla (X-linked anemia) Mouse: A Transient Neonatal Anemia Caused by a Gata1 Splicing Mutation by Miller, Kyle, Silvey, Michael, Logsdon, Derek, Balch, Frederick, Nsumu, Ndona, Sokolovsky, Inna, Gibson, Margaret, Bi, Chengpeng, Heruth, Daniel P., White, Robert A

Get full text

Mutation In Erythroid Specific Transcription Factor KLF1 Causes Hereditary Spherocytosis In the Nan (Neonatal Anemia) Hemolytic Anemia Mouse Model by White, Robert A, Heruth, Daniel P., Hawkins, Troy, Logsdon, Derek, Gibson, Margaret, Sokolovsky, Inna, Nsumu, Ndona, Major, Stephanie, Fegley, Barbara, Woods, Gerald, Lewing, Karen, Neville, Kathleen, Cornetta, Kenneth, Peterson, Kenneth

Get full text

A CAMERA GOES CAVING: COMPANY PHOTOGRAPHER BRITISH OXYGEN CO. LTD by Logsdon, Derek

Get full text

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2 by Manning, Brendan D, Logsdon, M Nicole, Lipovsky, Alex I, Abbott, Derek, Kwiatkowski, David J, Cantley, Lewis C

Get full text

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome by Baird, Denis A, Liu, Jimmy Z, Zheng, Jie, Sieberts, Solveig K, Perumal, Thanneer, Elsworth, Benjamin, Richardson, Tom G, Chen, Chia-Yen, Carrasquillo, Minerva M, Allen, Mariet, Reddy, Joseph S, De Jager, Philip L, Ertekin-Taner, Nilufer, Mangravite, Lara M, Logsdon, Ben, Estrada, Karol, Haycock, Philip C, Hemani, Gibran, Runz, Heiko, Smith, George Davey, Gaunt, Tom R

Get full text