Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3 -mutated acute myeloid leukemias: from... by Zhang, Weiguo, Ly, Charlie, Ishizawa, Jo, Mu, Hong, Ruvolo, Vivian, Shacham, Sharon, Daver, Naval, Andreeff, Michael

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Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy by Zhang, Weiguo, Yu, Guopan, Zhang, Hongying, Basyal, Mahesh, Ly, Charlie, Yuan, Bin, Ruvolo, Vivian, Piya, Sujan, Bhattacharya, Seemana, Zhang, Qi, Borthakur, Gautam, Battula, Venkata, Konopleva, Marina, Rice, William G, Andreeff, Michael

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The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and aurora kinases by Yu, Guopan, Zhang, Weiguo, Basyal, Mahesh, Nishida, Yuki, Mizumo, Hideaki, Ly, Charlie, Zhang, Hongying, Rice, William G, Andreeff, Michael

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FLT3 inhibitors upregulate CXCR4 and E-selectin ligands via ERK suppression in AML cells and CXCR4/E-selectin inhibition enhances anti-leukemia efficacy of FLT3-targeted therapy in... by Jia, Yannan, Zhang, Weiguo, Basyal, Mahesh, Chang, Kyung Hee, Ostermann, Lauren, Burks, Jared K., Ly, Charlie, Mu-Mosley, Hong, Zhang, Qi, Han, Xin, Fogler, William E., Magnani, John L., Lesegretain, Arnaud, Zal, Anna A., Zal, Tomasz, Andreeff, Michael

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The Pan-FLT3/BTK Multi-Kinase Inhibitor CG '806 Induces AML Killing in FLT-Mutant and Wild Type Cells, and Exerts Synergistic Pro-Apoptotic Effects with Concomitant Targeting of An... by Ly, Charlie, Zhang, Weiguo, Yu, Guopan, Mu, Hong, Zhang, Hongying, Rice, William, Andreeff, Michael

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CG '806, a Novel Pan-FLT3/BTK Multi-Kinase Inhibitor, Induces Cell Cycle Arrest, Apoptosis or Autophagy in AML Cells Depending on FLT3 Mutation Status by Yu, Guopan, Zhang, Weiguo, Ly, Charlie, Zhang, Hongying, Rice, William, Andreeff, Michael

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High-throughput proteomic profiling reveals mechanisms of action of AMG925, a dual FLT3-CDK4/6 kinase inhibitor targeting AML and AML stem/progenitor cells by Zeng, Zhihong, Ly, Charlie, Daver, Naval, Cortes, Jorge, Kantarjian, Hagop M., Andreeff, Michael, Konopleva, Marina

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Mechanism-Based Combinatorial Strategy for Overcoming FLT3-Inhibitor Resistance in Dual FLT3 ITD and TKD Point Mutations by Ly, Charlie, Zhang, Weiguo, Ruvolo, Vivian, Shah, Neil P., Andreeff, Michael

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AMG925, a Dual FLT3-CDK4/6 Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML Progenitor/Stem Cells by Zeng, Zhihong, Ly, Charlie, Mak, Duncan, Shah, Neil P., Konopleva, Marina, Andreeff, Michael

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Abstract 25: CG′806, a first-in-class FLT3/BTK inhibitor, exerts superior potency against AML cells harboring ITD, TKD and gatekeeper mutated FLT3 or wild-type FLT3 by Zhang, Weiguo, Zhang, Hongying, Local, Andrea, Rice, William G., Ly, Charlie J., Yu, Guopan, Howell, Stephen B., Andreeff, Michael

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Up-Regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-Cell Proliferation and Transforms T-Cells Towards a Tumor-Tolerating Phenotype by Jacamo, Rodrigo, Hoang, Nguyet-Minh, Al Rawi, Ahmed, Ly, Charlie, Parihar, Robin, McQueen, Teresa, Ruvolo, Peter P., Williams, Patrick, Alatrash, Gheath, Konopleva, Marina, Andreeff, Michael

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Concomitant Targeting of FLT3 and BTK with CG'806 Overcomes FLT3-Inhibitor Resistance through Inhibition of Autophagy by Zhang, Weiguo, Yu, Guopan, Zhang, Hongying, Ly, Charlie, Yuan, Bin, Ruvolo, Vivian, Piya, Sujan, Bhattacharya, Seemana, Zhang, Qi, Borthakur, Gautam, Battula, Venkata Lokesh, Konopleva, Marina Y., Rice, William G, Andreeff, Michael

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Dual E-Selectin/CXCR4 Antagonist GMI-1359 Exerts Efficient Anti-Leukemia Effects in a FLT3 ITD Mutated Acute Myeloid Leukemia Patient-Derived Xenograft Murine Model by Zhang, Weiguo, Ly, Charlie, Zhang, Qi, Mu, Hong, Battula, Venkata Lokesh, Patel, Nalini, Schober, Wendy, Han, Xin, Fogler, William E., Magnani, John L, Andreeff, Michael

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CG′806, a First-in-Class FLT3/BTK Inhibitor, Exerts Superior Potency against AML Cells Harboring ITD, TKD and Gatekeeper Mutated FLT3 or Wild-Type FLT3 by Zhang, Weiguo, Zhang, Hongying, Local, Andrea, Rice, Wiliam, Ly, Charlie, Yu, Guopan, Howell, Stephen, Andreeff, Michael

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LC-MS Characterization of Mesquite Flour Constituents by Young, Joshua E, Nguyen, Tina, Ly, Charlie, Jarman, Sunny, Diep, Diona, Pham, Cuong, Pesek, Joseph J, Matyska, Maria T, Takeoka, Gary R

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LC--MS characterization of mesquite flour constituents by Young, Joshua E, Nguyen, Tina, Ly, Charlie, Jarman, Sunny, Diep, Diona, Pham, Cuong, Pesek, Joseph J, Matyska, Maria T, Takeoka, Gary R

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Protein Nanoparticles as Drug Delivery Carriers for Cancer Therapy by Rojanasakul, Yon, Chen, Yi Charlie, Wang, Liying, Lohcharoenkal, Warangkana

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Size-Selective Nanoparticle Growth on Few-Layer Graphene Films by Luo, Zhengtang, Somers, Luke A, Dan, Yaping, Ly, Thomas, Kybert, Nicholas J, Mele, E. J, Johnson, A. T. Charlie

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Mapping the Stellar Halo with the H3 Spectroscopic Survey by Conroy, Charlie, Bonaca, Ana, Cargile, Phillip, Johnson, Benjamin D., Caldwell, Nelson, Naidu, Rohan P., Zaritsky, Dennis, Fabricant, Daniel, Moran, Sean, Rhee, Jaehyon, Szentgyorgyi, Andrew, Berlind, Perry, Calkins, Michael L., Kattner, ShiAnne, Ly, Chun

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Abstract 16918: COVID-19 Associated Acute Myocardial Injury With Prolonged Troponin Elevation by Tran, Ly, Ervin, Charlie, Thomas, Mathew J, Moore, David, Sampath, Rahul, Isserman, Steve

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