A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors by Becher, Oren J, Millard, Nathan E, Modak, Shakeel, Kushner, Brian H, Haque, Sofia, Spasojevic, Ivan, Trippett, Tanya M, Gilheeney, Stephen W, Khakoo, Yasmin, Lyden, David C, De Braganca, Kevin C, Kolesar, Jill M, Huse, Jason T, Kramer, Kim, Cheung, Nai-Kong V, Dunkel, Ira J

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Oligodendrocyte Progenitor Cells Promote Neovascularization in Glioma by Disrupting the Blood-Brain Barrier by YUJIE HUANG, HOFFMAN, Caitlin, LYDEN, David C, GREENFIELD, Jeffrey P, RAJAPPA, Prajwal, KIM, Joon-Hyung, WENHUO HU, HUSE, Jason, ZHONGSHU TANG, XURI LI, WEKSLER, Babette, BROMBERG, Jacqueline

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Genomic mapping of metastatic organotropism in lung adenocarcinoma by Lengel, Harry B., Mastrogiacomo, Brooke, Connolly, James G., Tan, Kay See, Liu, Yuan, Fick, Cameron N., Dunne, Elizabeth G., He, Di, Lankadasari, Manendra B., Satravada, Baby Anusha, Sun, Yichao, Kundra, Ritika, Fong, Chris, Smith, Shaleigh, Riely, Gregory J., Rudin, Charles M., Gomez, Daniel R., Solit, David B., Berger, Michael F., Li, Bob T., Mayo, Marty W., Matei, Irina, Lyden, David C., Adusumilli, Prasad S., Schultz, Nikolaus, Sanchez-Vega, Francisco, Jones, David R.

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Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas by Kerbel, Robert S, Benezra, Robert, Lyden, David C, Hattori, Koichi, Heissig, Beate, Nolan, Daniel J, Mittal, Vivek, Shaked, Yuval, Dias, Sergio, Bertolini, Francesco, Rafii, Shahin

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Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems by Khan, Imran, Gril, Brunilde, Hoshino, Ayuko, Yang, Howard H., Lee, Maxwell P., Difilippantonio, Simone, Lyden, David C., Steeg, Patricia S.

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A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors by Becher, Oren J., Gilheeney, Stephen W., Khakoo, Yasmin, Lyden, David C., Haque, Sofia, Braganca, Kevin C., Kolesar, Jill M., Huse, Jason T., Modak, Shakeel, Wexler, Leonard H., Kramer, Kim, Spasojevic, Ivan, Dunkel, Ira J.

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Breast adipose tissue‐derived extracellular vesicles from obese women alter tumor cell metabolism by Liu, Shuchen, Benito‐Martin, Alberto, Pelissier Vatter, Fanny A, Hanif, Sarah Z, Liu, Catherine, Bhardwaj, Priya, Sethupathy, Praveen, Farghli, Alaa R, Piloco, Phoebe, Paik, Paul, Mushannen, Malik, Dong, Xue, Otterburn, David M, Cohen, Leslie, Bareja, Rohan, Krumsiek, Jan, Cohen‐Gould, Leona, Calto, Samuel, Spector, Jason A, Elemento, Olivier, Lyden, David C, Brown, Kristy A

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Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells by Rajappa, Prajwal, Cobb, William S, Vartanian, Emma, Huang, Yujie, Daly, Laura, Hoffman, Caitlin, Zhang, Jane, Shen, Beiyi, Yanowitch, Rachel, Garg, Kunal, Cisse, Babacar, Haddock, Sara, Huse, Jason, Pisapia, David J, Chan, Timothy A, Lyden, David C, Bromberg, Jacqueline F, Greenfield, Jeffrey P

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KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma by Jones, Gregory D, Caso, Raul, Tan, Kay See, Mastrogiacomo, Brooke, Sanchez-Vega, Francisco, Liu, Yuan, Connolly, James G, Murciano-Goroff, Yonina R, Bott, Matthew J, Adusumilli, Prasad S, Molena, Daniela, Rocco, Gaetano, Rusch, Valerie W, Sihag, Smita, Misale, Sandra, Yaeger, Rona, Drilon, Alexander, Arbour, Kathryn C, Riely, Gregory J, Rosen, Neal, Lito, Piro, Zhang, Haiying, Lyden, David C, Rudin, Charles M, Jones, David R, Li, Bob T, Isbell, James M

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Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis by Zarnegar, Sara, Durham, Benjamin H., Khattar, Pallavi, Shukla, Neerav N., Benayed, Ryma, Lacouture, Mario E., Lavi, Ehud, Lyden, David C., Diamond, Eli L., Dunkel, Ira J., Abdel‐Wahab, Omar

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Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers by Bezdan, Daniela, Grigorev, Kirill, Meydan, Cem, Pelissier Vatter, Fanny A., Cioffi, Michele, Rao, Varsha, MacKay, Matthew, Nakahira, Kiichi, Burnham, Philip, Afshinnekoo, Ebrahim, Westover, Craig, Butler, Daniel, Mozsary, Chris, Donahoe, Timothy, Foox, Jonathan, Mishra, Tejaswini, Lucotti, Serena, Rana, Brinda K., Melnick, Ari M., Zhang, Haiying, Matei, Irina, Kelsen, David, Yu, Kenneth, Lyden, David C., Taylor, Lynn, Bailey, Susan M., Snyder, Michael P., Garrett-Bakelman, Francine E., Ossowski, Stephan, De Vlaminck, Iwijn, Mason, Christopher E.

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Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma by Dunkel, Ira J., Khakoo, Yasmin, Kernan, Nancy A., Gershon, Timothy, Gilheeney, Stephen, Lyden, David C., Wolden, Suzanne L., Orjuela, Manuela, Gardner, Sharon L., Abramson, David H.

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Webinar | Deciphering cancer: Understanding tumor invasion and the metastatic microenvironment by Lyden, David C., Rafii, Shahin

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High-quality Scanning Electron Microscopy Incorporated with a Freeze-drying and Gaseous Nitrogen-based Approach for Cell-extracellular Vesicle Interactions by Uryu, Kunihiro, Soplop, Nadine, Boudreau, Nancy, Kenific, Candia, Matei, Irina, Hashimoto, Ayako, Hoshino, Ayuko, Lyden, David C

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Exosomal MEK1 delays tumor growth by promoting anti-tumor immunity by Searles, Stephen, Lyden, David C, Bui, Jack D

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KRASG12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma by Jones, Gregory D., Caso, Raul, Tan, Kay See, Mastrogiacomo, Brooke, Sanchez-Vega, Francisco, Liu, Yuan, Connolly, James G., Murciano-Goroff, Yonina R., Bott, Matthew J., Adusumilli, Prasad S., Molena, Daniela, Rocco, Gaetano, Rusch, Valerie W., Sihag, Smita, Misale, Sandra, Yaeger, Rona, Drilon, Alexander, Arbour, Kathryn C., Riely, Gregory J., Rosen, Neal, Lito, Piro, Zhang, Haiying, Lyden, David C., Rudin, Charles M., Jones, David R., Li, Bob T., Isbell, James M.

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Id1 negatively regulates osteoclast differentiation and maintains hematopoietic stem cell niche homeostasis by Chan, April S, Jensen, Kristian K, Lederman, Hannah K, Kaplan, Rosandra N, Rivella, Stefano, Lyden, David C

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A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies by Gilheeney, Stephen W., Lyden, David C., Sgouros, Shirley, Antunes, Nuno, Gerald, William, Kramer, Kim, Lis, Eric, Meyers, Paul, Rosen, Nancy, Thaler, Howard T., Trippett, Tanya, Wexler, Leonard, Dunkel, Ira J.

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The Space Omics and Medical Atlas (SOMA) and international astronaut biobank by Overbey, Eliah G., Kim, JangKeun, Tierney, Braden T., Park, Jiwoon, Houerbi, Nadia, Lucaci, Alexander G., Garcia Medina, Sebastian, Damle, Namita, Najjar, Deena, Grigorev, Kirill, Afshin, Evan E., Ryon, Krista A., Sienkiewicz, Karolina, Klotz, Remi, Ortiz, Veronica, MacKay, Matthew, Schweickart, Annalise, Sierra, Maria A., Valenzuela, Matias F., Dantas, Ezequiel, Nelson, Theodore M., Foox, Jonathan, Narayanan, S. Anand, Schmidt, Caleb M., Schmidt, Michael A., Schmidt, Julian C., Mullane, Sean, Tigchelaar, Seth Stravers, Levitte, Steven, Westover, Craig, Bhattacharya, Chandrima, Lucotti, Serena, Wain Hirschberg, Jeremy, Proszynski, Jacqueline, Burke, Marissa, Kleinman, Ashley S., Loy, Conor, Mzava, Omary, Lenz, Joan, Paul, Doru, Mozsary, Christopher, Sanders, Lauren M., Taylor, Lynn E., Khan, Sharib A., Suhail Mohamad, Mir, Byhaqui, Syed Gufran Ahmad, Gajadhar, Aaron S., Tandel, Purvi, Yang, Qiu, Chu, Jessica, Benz, Ryan W., Siddiqui, Asim, Hornburg, Daniel, Blease, Kelly, Moreno, Juan, Boddicker, Andrew, Zhao, Junhua, Lajoie, Bryan, Scott, Ryan T., Gilbert, Rachel R., Lai Polo, San-huei, Altomare, Andrew, Kruglyak, Semyon, Levy, Shawn, Ariyapala, Ishara, Beer, Joanne, Zhang, Bingqing, Hudson, Briana M., Rininger, Aric, Church, Sarah E., Beheshti, Afshin, Church, George M., Smith, Scott M., Crucian, Brian E., Zwart, Sara R., Matei, Irina, Lyden, David C., Garrett-Bakelman, Francine, Krumsiek, Jan, Chen, Qiuying, Miller, Dawson, Shuga, Joe, Williams, Stephen, Nemec, Corey, Trudel, Guy, Pelchat, Martin, Laneuville, Odette, De Vlaminck, Iwijn, Gross, Steven, Bolton, Kelly L., Bailey, Susan M., Furman, David, Melnick, Ari M., Costes, Sylvain V., Shirah, Bader, Yu, Min, Menon, Anil S., Mateus, Jaime, Meydan, Cem, Mason, Christopher E.

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Abstract 4805: The role of exosomes in fibrosarcoma progression by Nakajima, Miho, Searles, Stephen C., Hoshino, Ayuko, Offer, Katherine M., Kenific, Candia M., Bui, Jack D., Lyden, David C.

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