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The discovery and structure-activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles as selective, CNS penetrating H1-antihistamines for insomnia
by
LAVRADOR-ERB, Karine
,
BABU RAVULA, Satheesh
,
CROWE, Paul D
,
BEATON, Graham
,
JINGHUA YU
,
ZAMANI-KORD, Said
,
MOREE, WilnaJ
,
PETROSKI, Robert E
,
JIANYUN WEN
,
MALANY, Siobhan
,
HOARE, Samuel R. J
,
MADAN, Ajay
Published in
Bioorganic & medicinal chemistry letters
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Journal Title
Bioorganic & Medicinal Chemistry Letters
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Subjects
Antagonist
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Antihistamines
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Benzimidazole
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Benzimidazoles - Chemical Synthesis
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Benzimidazoles - Chemistry
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Benzimidazoles - Therapeutic Use
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Biological And Medical Sciences
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Central Nervous System - Drug Effects
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Cns
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Drug Discovery
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Erg1 Potassium Channel
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Ether-A-Go-Go Potassium Channels - Metabolism
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Histamine H1 Antagonists - Chemical Synthesis
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Histamine H1 Antagonists - Chemistry
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Histamine H1 Antagonists - Therapeutic Use
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Humans
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Hypnotics. Sedatives
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Insomnia, Herg
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Medical Sciences
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Neuropharmacology
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Sciencedirect
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Sciencedirect Journals
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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