Folate and amine metabolites in senile dementia: a combined trial and biochemical study by Shaw, David M., Macsweeney, David A., Johnson, Anthony L., O'Keeffe, Ruth, Naidoo, D., Macleods, D. M., Jog, Sudha, Preece, John M., Crowley, J. M.

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Untreated clinical course of cerebral cavernous malformations: a prospective, population-based cohort study by Salman, Rustam Al-Shahi, Dr, Hall, Julie M, FRCR, Horne, Margaret A, MSc, Moultrie, Fiona, MBChB, Josephson, Colin B, MD, Bhattacharya, Jo J, FRCR, Counsell, Carl E, MD, Murray, Gordon D, Prof, Papanastassiou, Vakis, FRCS[SN], Ritchie, Vaughn, MBChB, Roberts, Richard C, DPhil, Sellar, Robin J, FRCR, Warlow, Charles P, Prof

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Prevalence, Awareness, Treatment, and Control of Hypertension in Rural and Urban Communities in High-, Middle-, and Low-Income Countries by Chow, Clara K, Teo, Koon K, Rangarajan, Sumathy, Islam, Shofiqul, Gupta, Rajeev, Avezum, Alvaro, Bahonar, Ahmad, Chifamba, Jephat, Dagenais, Gilles, Diaz, Rafael, Kazmi, Khawar, Lanas, Fernando, Wei, Li, Lopez-Jaramillo, Patricio, Fanghong, Lu, Ismail, Noor Hassim, Puoane, Thandi, Rosengren, Annika, Szuba, Andrzej, Temizhan, Ahmet, Wielgosz, Andy, Yusuf, Rita, Yusufali, Afzalhussein, McKee, Martin, Liu, Lisheng, Mony, Prem, Yusuf, Salim

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Breast-conserving surgery with or without irradiation in women aged 65 years or older with early breast cancer (PRIME II): a randomised controlled trial by Kunkler, Ian H, Prof, Williams, Linda J, PhD, Jack, Wilma J L, MBChB, Cameron, David A, Prof, Dixon, J Michael, Prof

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Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomis... by Beridze, Maia, Duley, Lelia, England, Timothy J, Ranta, Annemarei, Kok, J, Duignan, J, Rodriguez, M, Tennant, S, Furnace, J, Joyson, A, Smith, M, Grimwood, G, Reddan, J, Murphy, P, Benford, A, Hazel, B, Mashate, S, Gascoyne, R, Sivakumar, R, Garside, M, Lawrence, E, Watchurst, C, Chadha, D, Williams, R, Manawadu, D, Anderson, K, Wynter, I, Kambafwile, M, Arif, S, Beadle, H, Eveson, D, Datta, P, Bateman, G, Duodu, Y, Oliver, R, Barber, M, Esson, D, Brodie, F, Dent, M, Hammonds, F, Vernon, C, Faola, F, Riddell, V, Smith, A, Keshvara, R, Ryan, L, Tittle, A, Netherton, K, Persad, N, Ali, K, Ajao, T, Reader, M, Barrett, F, Harrington, F, Maddula, M, Clarke, M, Hedstrom, A, Keenan, S, Fletcher, G, Emsley, H, Finney, K, Grocott, J, Lyjko, S, Maguire, H, Sanyal, R, Balazikova, O, Button, D, Hubbuck, C, Storey, K, Campbell, E, Johnes, M, Keaveney, C, Marsden, T, Richards, E, Khanom, N, O'Reilly, J, Wilkinson, P, Young, E, Dizayee, K, Cochrane, H, O'Connell, J, Osborne, E, Brixey, S, Peters, J, Kumar, B, Platton, M, Cvoro, V, Couser, M, Wilkinson, D, Javaid, K, Orugun, O, Crowther, H, Jolly, R, Poultney, U, Metiu, M G, Hargroves, D, Buckley, C, Hayward, D, Lehman, A, Forrest, D

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Allopurinol versus usual care in UK patients with ischaemic heart disease (ALL-HEART): a multicentre, prospective, randomised, open-label, blinded-endpoint trial by Mackenzie, Isla S, Hawkey, Christopher J, Ford, Ian, Greenlaw, Nicola, Pigazzani, Filippo, Rogers, Amy, Struthers, Allan D, Begg, Alan G, Wei, Li, Avery, Anthony J, Taggar, Jaspal S, Walker, Andrew, Duce, Suzanne L, Barr, Rebecca J, Dumbleton, Jennifer S, Rooke, Evelien D, Townend, Jonathan N, Ritchie, Lewis D, MacDonald, Thomas M, Ahmed, Husnat, Arthur, Peter, Aziz, Jane, Barnes, Lawrence, Boyle, Sarah, Brighton, Tom, Brown, Morris, Caulfield, Mark, Dawson, Jesse, Denvir, Martin, Doney, Alexander SF, Doshi, Sagar, Dryburgh, Moira, Eddleston, Michael, Finlayson, Jim, Fuat, Ahmet, Furnace, Jacqueline, Grieve, JW Kerr, Guthrie, Greg, Ham, Sharon, Isaard, Emma, Jennings, Claudine, Johnson, Richard, Kerr, Claire, Khan, Sohail, Krishnan, Kailash, Long, Susan, Mackintosh, Anne, Macleod, Mary Joan, McCormack, Terry, McEleny, Paul, Morar, Monique, Nadir, Adnan, Newby, David, Petrie, Colin, Preiss, David, Ralston, Stuart, Randall, Marc, Routledge, Helen, Shakir, Saad, Sharma, Raj, Shepherd, Bridget, Sims, Don, Snedden, Gordon, Trevelyan, Jasper, Weir, Christopher, Weir, Robin, Wetherall, Kirsty, Wilson, Robbie, Wilson, Adam, Zutis, Kris

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Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiologica... by Yusuf, Salim, Prof, Islam, Shofiqul, MSc, Chow, Clara K, PhD, Rangarajan, Sumathy, MSc, Dagenais, Gilles, Prof, Diaz, Rafael, MD, Gupta, Rajeev, PhD, Kelishadi, Roya, Prof, Iqbal, Romaina, PhD, Avezum, Alvaro, MD, Kruger, Annamarie, Prof, Kutty, Raman, Prof, Lanas, Fernando, MD, Lisheng, Liu, Prof, Wei, Li, Prof, Lopez-Jaramillo, Patricio, Prof, Oguz, Aytekin, MD, Rahman, Omar, Prof, Swidan, Hany, MD, Yusoff, Khalid, Prof, Zatonski, Witold, Prof, Rosengren, Annika, Prof, Teo, Koon K, Prof

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Long-term effectiveness of dopamine agonists and monoamine oxidase B inhibitors compared with levodopa as initial treatment for Parkinson's disease (PD MED): a large, open-label, p... by Gray, Richard, Ives, Natalie, Rick, Caroline, Patel, Smitaa, Gray, Alastair, Jenkinson, Crispin, McIntosh, Emma, Wheatley, Keith, Williams, Adrian, Clarke, Carl E

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A European Renal Best Practice (ERBP) position statement on the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines on Acute Kidney Injury: Part 1: defini... by FLISER, Danilo, LAVILLE, Maurice, COVIC, Adrian, FOUQUE, Denis, VANHOLDER, Raymond, JUILLARD, Laurent, VAN BIESEN, Wim

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Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicent... by Hofmeijer, Jeannette, MD, Kappelle, L Jaap, MD, Algra, Ale, MD, Amelink, G Johan, MD, van Gijn, Jan, FRCP, van der Worp, H Bart, MD

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Prevalence of a Healthy Lifestyle Among Individuals With Cardiovascular Disease in High-, Middle- and Low-Income Countries: The Prospective Urban Rural Epidemiology (PURE) Study by Teo, Koon, Lear, Scott, Islam, Shofiqul, Mony, Prem, Dehghan, Mahshid, Li, Wei, Rosengren, Annika, Lopez-Jaramillo, Patricio, Diaz, Rafael, Oliveira, Gustavo, Miskan, Maizatullifah, Rangarajan, Sumathy, Iqbal, Romaina, Ilow, Rafal, Puone, Thandi, Bahonar, Ahmad, Gulec, Sadi, Darwish, Ebtihal A, Lanas, Fernando, Vijaykumar, Krishnapillai, Rahman, Omar, Chifamba, Jephat, Hou, Yan, Li, Ning, Yusuf, Salim

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Moving knowledge into action for more effective practice, programmes and policy: protocol for a research programme on integrated knowledge translation by Graham, Ian D, Kothari, Anita, McCutcheon, Chris

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Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial by Sullivan, Frank, Rojas, Javier, Lowe, Gordon, McGill, Connor, Palmer, Jeb, Parakramawansha, Ruwan, MacRaild, Allan, Parry-Jones, Adrian, Johnes, Mary, Wood, Edith, Owoyele, Emmanuelle, Ballantine, Robert, Maatouk, Ahmad, Dakin, Katy, Szabo, Susan, Tysoe, Sharon, Esson, Derek, Anjum, Talat, Quinn, Leanne, Chenna, Srikanth, Gainard, Glyn, Butler, Adrian, Shelton, Faye, Havard, Diane, Board, Joanne, Murali, Elodie, Adie, Katja, Bond, Kirsty, Mudd, Paul, Moreton, Fiona, Huang, Xuya, Gartrell, Imogen, Smith, Simon, Hewitt, Jonathan, Banaras, Azra, Bakawala, Rehana, Manoj, Aravind, Sharma, Nikhil, Gbadamoshi, Lukuman, Bell, Jo, Longland, Barbara, Harrison, Melanie, Stevenson, Sarah, Jagpal, Baljit, Nelson, Sandra, Webber, Adam, Tayler, Michelle, Clayton, Susan, Gamble, Ed, Grimwood, Gemma, Reckless, Ian, Finlay, Sarah, Hayhoe, Helen, Tallantyre, Emma, White, Susan, Reddan, Julie, Jarrett, David, Harrington-Davies, Yasmin, Shahmehri, Shahrzad, Henry, Margo, Hazel, Beth, Shah, Alex, Datta, Prabal, Thompson, Teresa, Herman, Jane, Howard, Joanne, Dhar, Saikat, Baird, Yolanda, Davies, Ruth, Little, Victoria, Cherian, Suja, Cunningham, Mishell, Zahoor, Tajammal, Webster, Timothy, Jenkins, Colin, Hughes, Claire, Whitcher, Alison, Ravenhill, Garth, Saada, Janak, Perfitt, Rebekah, Tauro, Suzanne, Cuddy, Sarah, Markova, Skarlet, Thomas, Isobel, Sekaran, Lakshmanan, Elfandi, Khaled, Salehin, Maqsud, Ghaly, George, Horton, Sarah, Bell, Murdina, Gilham, Ellie, Fuller, Tracy, Goorah, Neetish, Bell, Angela, Kelly, Christine, Tomlinson, Benjamin, Donaldson, Denise, Kenton, Antony, Subramonian, Santhosh, Owusu-Agyei, Peter

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Safety and tolerability of SCH 530348 in patients undergoing non-urgent percutaneous coronary intervention: a randomised, double-blind, placebo-controlled phase II study by Becker, Richard C, Prof, Moliterno, David J, Prof, Jennings, Lisa K, Prof, Pieper, Karen S, MS, Pei, Jinglan, MS, Niederman, Alan, MD, Ziada, Khaled M, MD, Berman, Gail, MD, Strony, John, MD, Joseph, Diane, Mahaffey, Kenneth W, MD, Van de Werf, Frans, Prof, Veltri, Enrico, MD, Harrington, Robert A, Prof

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Frequency and Patterns of Brain Infarction in Patients With Embolic Stroke of Undetermined Source: NAVIGATE ESUS Trial by Sharma, Mukul, Smith, Eric E., Pearce, Lesly A., Shoamanesh, Ashkan, Perera, Kanjana S., Coutts, Shelagh B., Damgaard, Dorte, Ameriso, Sebastian F., Rha, Joung-Ho, Modrau, Boris, Yoon, Byung-Woo, Romano, Marina, Messé, Steven R., Barlinn, Jessica, Lambeck, Johann, Saad, Feryal, Berkowitz, Scott D., Mundl, Hardi, Connolly, Stuart J., Hart, Robert G.

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Widespread non-adherence to guidelines in the operative management of diabetes-related foot disease complications

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The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3])... by Sandercock, Peter, Wardlaw, Joanna M, Lindley, Richard I, Dennis, Martin, Cohen, Geoff, Murray, Gordon, Innes, Karen, Venables, Graham, Czlonkowska, Anna, Kobayashi, Adam, Ricci, Stefano, Murray, Veronica, Berge, Eivind, Slot, Karsten Bruins, Hankey, Graeme J, Correia, Manuel, Peeters, Andre, Matz, Karl, Lyrer, Phillippe, Gubitz, Gord, Phillips, Stephen J, Arauz, Antonio

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A Computational Account of the Production Effect: Still Playing Twenty Questions With Nature by Jamieson, Randall K., Mewhort, D. J. K., Hockley, William E.

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Patient care and clinical outcomes for patients with COVID-19 infection admitted to African high-care or intensive care units (ACCCOS): a multicentre, prospective, observational co... by Miller, Malcolm, Michell, William Lance, Aniteye, Ernest, Elhadi, Muhammed, Fawzy, Maher, Fredericks, David, Gebre, Meseret, Hardy, Anneli, Joubert, Ivan, Macleod, Kieran, Mekonnen, Zelalem, Msosa, Vanessa, Ndonga, Andrew, Ngumi, Zipporah, Piercy, Jenna Louise, Taylor, Elliott H, van Straaten, Dawid, Awad, Ahmed, Shaban, Mahmoud, Elmehrath, Ahmed O, Elganainy, Mohamed, Essam, Mahmoud, Ali, Aboubakr, Hussein, Aliae Mohamed, kamel, Emad Zarief, Ahmed, Islam, Rafaat, Nashwa, Azzam, Ahmed, Azab, Mohammed, Ghozy, Sherief, El Kassas, Mohamed, Azzam, Aml, Elmandouh, Omar, Addisie, Abebe, Eshete, Akine, Desita, Kokeb, Agidew, Yared, Tesfaye, Emnet, Hailemariam, Gelaw, Keneni, Dame Fikadu, Gemechu, Tirunesh Busha, Abera, Elias Tewabe, Lawson, Aba, Sottie, Daniel Akwanfo, Obeng, William, Bitta, Caesar, Yahya, Mohammed Mahdi Ali, Majeed, Elsalhein, Abusalama, Abdurraouf A, Alziyituni, Zainab, Gamra, Marwa F, Khel, Samer, Adam, Safia, Alsoufi, Ahmed, Binnawara, Muhannad, Msherghi, Ahmed, Bouhuwaish, Ahmad Elmabri Mohammad, Taher, Ahmed SA, Mabedi, Delia, Lorenzoni, Cesaltina, Mambo, Jorge, Mamane, Maikassoua, Adesoji Ademuyiwa, Adesoji Ademuyiwa, Adeyeye, Ademola, Orshio, Donald, Isamade, Erdoo Suckie, Embu, Henry, Nuhu, Samuel, Ojiakor, Samuel, Nuhu, Ahmed, Kwayabura, Salisu, Fowotade, Adeola, Sanusi, Arinola, Osinaike, Babatunde, Idowu, Olusola, Amali, Abdullahi Oteikwu, Ibrahim, Sanusi, Kida, Ibrahim, Scribante, Juan, Kalla, Ismail Sikander, Mdladla, Aurence, Matos-Puig, Roel, Ramkillawan, Arisha, Devenish, Liam, Fernandes, Nicole, Grabowski, Nicola, Rammego, Mapule, Dhlamini, Masikhanyise Elizabeth, Neuhoff, Matthew, Kabambi, Freddy, Dickerson, Roger, Moletsane, Godfrey, Loots, Helene, Vorster, Frans Christiaan, Sebastian, Melinda, Rheeder, Paul, van Hougenhouck-Tulleken, Wesley, van der Linde, Pieter, Swart, Reinier, Govender, Veneshree

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Perioperative intravenous contrast administration and the incidence of acute kidney injury after major gastrointestinal surgery: prospective, multicentre cohort study by Ahmed, WUR, Claireaux, HA, Patel, P, Barai, I, Fearnhead, N, Falamarzi, A, Perai, K Gascon, Hopkins, M, McCartan, N, Cabdi, N M O, Galea, M, Looi, W L, Kerr, M, Seetharam, P, Schramm, M, Tan, C Yan, Sanders, E, Jain, P, Verma, N, Dindyal, S, Menon, D, Turner, J, Karbowiak, M, Searle, C, Brown, R, Concannon, K, Crilly, C, Stringfellow, T D, Murtaza, A, Power, A, Marimuthu, K, Kersey, T, Carter, R, Rai, A, Khan, K, Roberts, G, Stewart, D, Imam, S Z, Perry, C, King, S, Ramjas, D, Bath, M F, Cruddas, L, Osei‐Bordom, D, Trenear, R, Clements, S E, Rogers, D, Thachettu, A, Do, V, Thomas, A, Hernon, J, Shurovi, B N, Cohen, J, Cullum, R, Phillips, J, Zhu, Y, Keyte, A, Gnanappiragasam, D, Lex, J, McGeorge, E, Rodman, L, Davies, E, Thompson, J, Hanson, M, Riley, B J, Yates, J, Varcada, M, Church, R, Osborn, G, Kremel, D, Hammad, A, Torrance, H D, Haq, T, McDowell, E, Ramsden, J, Rajendran, S, Bull, K, Sultan, S, Sen, P, Bhome, R, Elliott, J, Jones, A, Lim, D, Roe, T, Mecia, L, Powell, C, Sureshkumar, A, Salman, M, Jones, C, Yin, Z D, Ross, F, Sajid, M, Lakin, F, Alberts, J, Crewe, A, Ubhi, H K, Adeogun, A, Davison, C, Babatunde, F, Chandler, S

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