Pharmacokinetics and Pharmacodynamics of AR9281, an Inhibitor of Soluble Epoxide Hydrolase, in Single- and Multiple-Dose Studies in Healthy Human Subjects by Chen, Dawn, Whitcomb, Randall, MacIntyre, Euan, Tran, Vinh, Do, Zung N., Sabry, James, Patel, Dinesh V., Anandan, Sampath K., Gless, Richard, Webb, Heather K.

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1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: Application in the synthesis of potent human melanocortin-4 receptor selective agonists by Bakshi, Raman K., Hong, Qingmei, Olson, J.T., Ye, Zhixiong, Sebhat, Iyassue K., Weinberg, David H., MacNeil, Tanya, Kalyani, Rubana N., Tang, Rui, Martin, William J., Strack, Alison, McGowan, Erin, Tamvakopoulos, Constantin, Miller, Randy R., Stearns, Ralph A., Tang, Wei, Maclntyre, D. Euan, van der Ploeg, Lex H.T., Patchett, Arthur A., Nargund, Ravi P.

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1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypert... by Anandan, Sampath-Kumar, Webb, Heather Kay, Chen, Dawn, Wang, Yi-Xin (Jim), Aavula, Basker R., Cases, Sylvaine, Cheng, Ying, Do, Zung N., Mehra, Upasana, Tran, Vinh, Vincelette, Jon, Waszczuk, Joanna, White, Kathy, Wong, Kenneth R., Zhang, Le-Ning, Jones, Paul D., Hammock, Bruce D., Patel, Dinesh V., Whitcomb, Randall, MacIntyre, D. Euan, Sabry, James, Gless, Richard

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A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis by Walker, Matthew, Campbell, Barry R, Azer, Karim, Tong, Christopher, Fang, Kaijie, Cook, Jacquelynn J, Forrest, Michael J, Kempadoo, Kimberly, Wright, Samuel D, Saltzman, Jeffrey S, MacIntyre, Euan, Hargreaves, Richard

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Cyclopentane-based human NK1 antagonists. Part 2: Development of potent, orally active, water-soluble derivatives by Meurer, Laura C., Finke, Paul E., Owens, Karen A., Tsou, Nancy N., Ball, Richard G., Mills, Sander G., MacCoss, Malcolm, Sadowski, Sharon, Cascieri, Margaret A., Tsao, Kwei-Lan, Chicchi, Gary G., Egger, Linda A., Luell, Silvi, Metzger, Joseph M., MacIntyre, D. Euan, Rupniak, Nadia M.J., Williams, Angela R., Hargreaves, Richard J.

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Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands by Hong, Qingmei, Bakshi, Raman K., Dellureficio, James, He, Shuwen, Ye, Zhixiong, Dobbelaar, Peter H., Sebhat, Iyassu K., Guo, Liangqin, Liu, Jian, Jian, Tianying, Tang, Rui, Kalyani, Rubana N., MacNeil, Tanya, Vongs, Aurawan, Rosenblum, Charles I., Weinberg, David H., Peng, Qingping, Tamvakopoulos, Constantin, Miller, Randy R., Stearns, Ralph A., Cashen, Doreen, Martin, Willian J., Chen, Airu S., Metzger, Joseph M., Chen, Howard Y., Strack, Allison M., Fong, Tung M., Maclntyre, Euan, Van der Ploeg, Lex H.T., Wyvratt, Matthew J., Nargund, Ravi P.

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Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats by Shearman, Lauren P., Camacho, Ramon E., Sloan Stribling, D., Zhou, Dan, Bednarek, Maria A., Hreniuk, Donna L., Feighner, Scott D., Tan, Carina P., Howard, Andrew D., Van der Ploeg, Lex H.T., MacIntyre, D.Euan, Hickey, Gerard J., Strack, Alison M.

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Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents by SHEARMAN, Lauren P, SLOAN STRIBLING, D, SPANN, Stephanie K, MACNEIL, Douglas J, FONG, Tung M, METZGER, Joseph M, GOULET, Mark T, HAGMANN, William K, PLUMMER, Christopher W, FINKE, Paul E, MILLS, Sander G, SHAH, Shrenik K, CAMACHO, Ramon E, TRUONG, Quang, VAN DER PLOEG, L. H. T, EUAN MACINTYRE, D, STRACK, Alison M, ROSKO, Kimberly M, JUNYING WANG, TONG, Sharon, YUE FENG, MARSH, Donald J, HONG YU, XIAOMING GUAN

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Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide... by Guthikonda, Ravindra N., Shah, Shrenik K., Pacholok, Stephen G., Humes, John L., Mumford, Richard A., Grant, Stephan K., Chabin, Renee M., Green, Barbara G., Tsou, Nancy, Ball, Richard, Fletcher, Daniel S., Luell, Silvi, Euan MacIntyre, D., MacCoss, Malcolm

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Discovery of an orally bioavailable alkyl oxadiazole β3 adrenergic receptor agonist by FENG, D. D, BIFTU, T, MILLER, R. R, STEARNS, R. A, STRADER, C. D, TOTA, L, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F, LIPING DENG, FEENEY, W. P, FORREST, M. J, HOM, G. J, MACLNTYRE, D. E

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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective β3 adrenergic receptor agonist antiobesity agents by BIFTU, T, FENG, D. D, FORREST, M. J, HOM, G. J, MACLNTYRE, D. E, STEARNS, R. A, STRADER, C. D, WYVRATT, M. J, FISHER, M. H, WEBER, A. E, LIANG, G.-B, KUO, H, XIAOXIA QIAN, NAYLOR, E. M, COLANDREA, V. J, CANDELORE, M. R, CASCIERI, M. A, COLWELL, L. F

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Molecular approaches to the discovery of new treatments for obesity by Strader, Catherine D, MacIntyre, D Euan, Candelore, Mari R, Parker, Eric M

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