Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor by Garcia Fortanet, Jorge, Chen, Christine Hiu-Tung, Chen, Ying-Nan P, Chen, Zhouliang, Deng, Zhan, Firestone, Brant, Fekkes, Peter, Fodor, Michelle, Fortin, Pascal D, Fridrich, Cary, Grunenfelder, Denise, Ho, Samuel, Kang, Zhao B, Karki, Rajesh, Kato, Mitsunori, Keen, Nick, LaBonte, Laura R, Larrow, Jay, Lenoir, Francois, Liu, Gang, Liu, Shumei, Lombardo, Franco, Majumdar, Dyuti, Meyer, Matthew J, Palermo, Mark, Perez, Lawrence, Pu, Minying, Ramsey, Timothy, Sellers, William R, Shultz, Michael D, Stams, Travis, Towler, Christopher, Wang, Ping, Williams, Sarah L, Zhang, Ji-Hu, LaMarche, Matthew J

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Identification of NVP-TNKS656: The Use of Structure–Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor by Shultz, Michael D, Cheung, Atwood K, Kirby, Christina A, Firestone, Brant, Fan, Jianmei, Chen, Christine Hiu-Tung, Chen, Zhouliang, Chin, Donovan N, DiPietro, Lucian, Fazal, Aleem, Feng, Yun, Fortin, Pascal D, Gould, Ty, Lagu, Bharat, Lei, Huangshu, Lenoir, Francois, Majumdar, Dyuti, Ochala, Etienne, Palermo, M. G, Pham, Ly, Pu, Minying, Smith, Troy, Stams, Travis, Tomlinson, Ronald C, Touré, B. Barry, Visser, Michael, Wang, Run Ming, Waters, Nigel J, Shao, Wenlin

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Hexafluoroisopropanol for the Selective Deactivation of Poisonous Nucleophiles Enabling Catalytic Asymmetric Cyclopropanation of Complex Molecules by Sharland, Jack C., Dunstan, David, Majumdar, Dyuti, Gao, Jinhai, Tan, Kian, Malik, Hasnain A., Davies, Huw M. L.

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Use of Green Solvents in Metallaphotoredox Cross-Electrophile Coupling Reactions Utilizing a Lipophilic Modified Dual Ir/Ni Catalyst System by Delgado, Pete, Glass, Raoul J, Geraci, Gina, Duvadie, Rohit, Majumdar, Dyuti, Robinson, Richard I, Elmaarouf, Imran, Mikus, Malte, Tan, Kian L

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Dual Allosteric Inhibition of SHP2 Phosphatase by Fodor, Michelle, Price, Edmund, Wang, Ping, Lu, Hengyu, Argintaru, Andreea, Chen, Zhouliang, Glick, Meir, Hao, Huai-Xiang, Kato, Mitsunori, Koenig, Robert, LaRochelle, Jonathan R, Liu, Gang, McNeill, Eric, Majumdar, Dyuti, Nishiguchi, Gisele A, Perez, Lawrence B, Paris, Gregory, Quinn, Christopher M, Ramsey, Timothy, Sendzik, Martin, Shultz, Michael David, Williams, Sarah L, Stams, Travis, Blacklow, Stephen C, Acker, Michael G, LaMarche, Matthew J

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Correction to “MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery” by Brocklehurst, Cara E., Altmann, Eva, André, Jérôme, Bon, Corentin, Caya, Thomas, Davis, Holly, Decoret, Odile, Dunstan, David, Ertl, Peter, Ginsburg-Moraff, Carol, Grob, Jonathan, Gosling, Daniel J., Lapointe, Guillaume, Majumdar, Dyuti, Marziale, Alexander N., Mues, Heinrich, Palmieri, Marco, Racine, Sophie, Robinson, Richard I., Springer, Clayton, Tan, Kian, Ulmer, William, West, Laura, Wyler, René

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Abstract 2808: Simultaneous inhibition of SHP2 phosphatase at two allosteric sites by Fodor, Michelle, Price, Edmund, Wang, Ping, Lu, Hengyu, Argintaru, Andreea, Chen, Zhouliang, Glick, Meir, Hao, Huai-Xiang, Kato, Mitsunori, Koenig, Robert, LaRochelle, Jonathan R., Liu, Gang, McNeill, Eric, Majumdar, Dyuti, Nishiguchi, Gisele, Perez, Lawrence, Paris, Greg, Quinn, Christopher, Ramsey, Timothy, Sendzik, Martin, Shultz, Michael, Williams, Sarah, Stams, Travis, Blacklow, Stephen C., LaMarche, Matthew J., Acker, Michael G.

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Structure–Efficiency Relationship of [1,2,4]Triazol-3-ylamines as Novel Nicotinamide Isosteres that Inhibit Tankyrases by Shultz, Michael D, Majumdar, Dyuti, Chin, Donovan N, Fortin, Pascal D, Feng, Yun, Gould, Ty, Kirby, Christina A, Stams, Travis, Waters, Nigel J, Shao, Wenlin

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Optimization of the in Vitro Cardiac Safety of Hydroxamate-Based Histone Deacetylase Inhibitors by Shultz, Michael D, Cao, Xueying, Chen, Christine H, Cho, Young Shin, Davis, Nicole R, Eckman, Joe, Fan, Jianmei, Fekete, Alex, Firestone, Brant, Flynn, Julie, Green, Jack, Growney, Joseph D, Holmqvist, Mats, Hsu, Meier, Jansson, Daniel, Jiang, Lei, Kwon, Paul, Liu, Gang, Lombardo, Franco, Lu, Qiang, Majumdar, Dyuti, Meta, Christopher, Perez, Lawrence, Pu, Minying, Ramsey, Tim, Remiszewski, Stacy, Skolnik, Suzanne, Traebert, Martin, Urban, Laszlo, Uttamsingh, Vinita, Wang, Ping, Whitebread, Steven, Whitehead, Lewis, Yan-Neale, Yan, Yao, Yung-Mae, Zhou, Liping, Atadja, Peter

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Abstract 2084: Conformational activation and allosteric inhibition of SHP2 in RTK-driven cancers by Acker, Michael G., Chen, Ying-Nan P., LaMarche, Matthew J., Chan, Ho Man, Fekkes, Peter, Garcia-Fortanet, Jorge, LaRochelle, Jonathan R., Antonakos, Brandon, Chen, Christine Hiu-Tung, Chen, Zhuoliang, Cooke, Vesselina G., Dobson, Jason R., Deng, Zhan, Feng, Fei, Firestone, Brant, Fodor, Michelle, Fridrich, Cary, Gao, Hui, Hao, Huai-Xiang, Jacob, Jaison, Ho, Samuel, Hsiao, Kathy, Kang, Zhao B., Karki, Rajesh, Kato, Mitsunori, Larrow, Jay, Bonte, Laura R. La, Liu, Gang, Liu, Shumei, Majumdar, Dyuti, Meyer, Matthew J., Palermo, Mark, Pu, Minying, Price, Edmund, Shakya, Subarna, Shultz, Michael D., Venkatesan, Kavitha, Wang, Ping, Warmuth, Markus, Williams, Sarah, Yang, Guizhi, Yuan, Jing, Zhang, Ji-Hu, Zhu, Ping, Blacklow, Stephen C., Ramsey, Timothy, Keen, Nicholas J., Sellers, William R., Stams, Travis, Fortin, Pascal D.

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Indanylacetic Acid Derivatives Carrying 4-Thiazolyl-phenoxy Tail Groups, a New Class of Potent PPAR α/γ/δ Pan Agonists:  Synthesis, Structure−Activity Relationship, and In Vivo Eff... by Rudolph, Joachim, Chen, Libing, Majumdar, Dyuti, Bullock, William H, Burns, Michael, Claus, Thomas, Dela Cruz, Fernando E, Daly, Michelle, Ehrgott, Frederick J, Johnson, Jeffrey S, Livingston, James N, Schoenleber, Robert W, Shapiro, Jeffrey, Yang, Ling, Tsutsumi, Manami, Ma, Xin

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