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Arginine 595 is duplicated in patients with acute leukemias carrying internal tandem duplications of FLT3 and modulates its transforming potential
by
Vempati, Sridhar
,
Reindl, Carola
,
Kaza, Seshu Kumar
,
Kern, Ruth
,
Malamoussi, Theodora
,
Dugas, Martin
,
Mellert, Gudrun
,
Schnittger, Susanne
,
Hiddemann, Wolfgang
,
Spiekermann, Karsten
Published in
Blood
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Arginine (R) at Position 595 in FLT3 Is Critical for Transforming Potential of FLT3-Length Mutations
by
Vempati, Sridhar
,
Schwab, Ruth
,
Malamoussi, Theodora
,
Dugas, Martin
,
Mellert, Gudrun
,
Schnittger, Susanne
,
Hiddemann, Wolfgang
,
Spiekermann, Karsten
Published in
Blood
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Blood
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Subjects
Adult
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Aged
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Aged, 80 And Over
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Amino Acid Substitution
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1
Arginine
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1
Biological And Medical Sciences
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Cell Transformation, Neoplastic - Genetics
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Female
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Fms-Like Tyrosine Kinase 3 - Genetics
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Gene Duplication
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Hematologic And Hematopoietic Diseases
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Hematology
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Humans
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Leukemia - Genetics
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Leukemias. Malignant Lymphomas. Malignant Reticulosis. Myelofibrosis
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Life Sciences & Biomedicine
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Male
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Medical Sciences
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Middle Aged
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Mutagenesis
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Elsevier Sciencedirect Journals
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