Evaluation of the potential for pharmacokinetic and pharmacodynamic interactions between dutogliptin, a novel DPP4 inhibitor, and metformin, in type 2 diabetic patients by Li, Jianke, Klemm, Kirsti, Marie O'Farrell, A., Guler, Hans-Peter, Cherrington, Julie M., Schwartz, Sherwyn, Boyea, Teresa

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Pharmacokinetic and Pharmacodynamic Assessments of the Dipeptidyl Peptidase-4 Inhibitor PHX1149: Double-Blind, Placebo-Controlled, Single- and Multiple-Dose Studies in Healthy Subj... by O'Farrell, A. Marie, PhD, van Vliet, Andre, MD,PhD, Abou Farha, Khalid, MD,PhD, Cherrington, Julie M., PhD, Campbell, David A., PhD, Li, Xinqiang, PhD, Hanway, Denise, MS, Li, Jianke, PhD, Guler, Hans-Peter, MD

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Pharmacokinetics and antiviral activity of PHX1766, a novel HCV protease inhibitor, using an accelerated Phase I study design by HOTHO, Daphne M, DE BRUIJNE, Joep, SCHINKEL, Janke, MOLENKAMP, Richard, DE WETERING DE ROOIJ, Jeroen Van, VLIET, Andre Van, JANSSEN, Harry La, DE KNEGT, Robert J, REESINK, Hendrik W, O'FARRELL, A. Marie, BOYEA, Teresa, JIANKE LI, BRACKEN, Michele, XIN LI, CAMPBELL, David, GULER, Hans-Peter, WEEGINK, Christine J

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IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways by O'Farrell, Anne-Marie, Liu, Ying, Moore, Kevin W., Mui, Alice L.-F.

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Efficacy of Behavioral Couples Therapy Versus Individual Recovery Counseling for Addressing Posttraumatic Stress Disorder Among Women With Drug Use Disorders by Schumm, Jeremiah A., O'Farrell, Timothy J., Murphy, Marie M., Muchowski, Patrice

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Tradeoffs between fisheries harvest and the resilience of coral reefs by Bozec, Yves-Marie, O’Farrell, Shay, Bruggemann, J. Henrich, Luckhurst, Brian E., Mumby, Peter J.

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First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors by Falchook, Gerald, Infante, Jeffrey, Arkenau, Hendrik-Tobias, Patel, Manish R., Dean, Emma, Borazanci, Erkut, Brenner, Andrew, Cook, Natalie, Lopez, Juanita, Pant, Shubham, Frankel, Arthur, Schmid, Peter, Moore, Kathleen, McCulloch, William, Grimmer, Katharine, O'Farrell, Marie, Kemble, George, Burris, Howard

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Host autophagy mediates organ wasting and nutrient mobilization for tumor growth by Khezri, Rojyar, Holland, Petter, Schoborg, Todd Andrew, Abramovich, Ifat, Takáts, Szabolcs, Dillard, Caroline, Jain, Ashish, O'Farrell, Fergal, Schultz, Sebastian Wolfgang, Hagopian, William M, Quintana, Eduardo Martin, Ng, Rachel, Katheder, Nadja Sandra, Rahman, Mohammed Mahidur, Teles Reis, José Gerardo, Brech, Andreas, Jasper, Heinrich, Rusan, Nasser M, Jahren, Anne Hope, Gottlieb, Eyal, Rusten, Tor Erik

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Fatty acid synthase - Modern tumor cell biology insights into a classical oncology target by Buckley, Douglas, Duke, Gregory, Heuer, Timothy S, O'Farrell, Marie, Wagman, Allan S, McCulloch, William, Kemble, George

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A Randomized Clinical Trial of Behavioral Couples Therapy Versus Individually-Based Treatment for Drug-Abusing Women by O'Farrell, Timothy J., Schumm, Jeremiah A., Murphy, Marie M., Muchowski, Patrice M.

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THU-231 Combination of fatty acid synthase (FASN) inhibitor and thyroid hormone receptor beta (THRb) agonist, resmetirom, improved markers of NASH and cardiovascular health in LDL... by Tsai, Wen-Wei, Gart, Eveline, Morrison, Martine C., Stokman, Geurt, Martins, Eduardo, Kemble, George, O'Farrell, Marie

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p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model by HOI YEE CHOW, JUBB, Adrian M, SILVIO GUTKIND, J, HOEFLICH, Klaus P, CHERNOFF, Jonathan, KOCH, Jennifer N, JAFFER, Zahara M, STEPANOVA, Dina, CAMPBELL, David A, DURON, Sergio G, O'FARRELL, Marie, CAI, Kathy Q, KLEIN-SZANTO, Andres J. P

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Cytosponge-trefoil factor 3 versus usual care to identify Barrett's oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial by Muldrew, Beth, Gehrung, Marcel, Tripathi, Monika, Smith, Samuel G, Muddu, Ajay, Northrop, Alex, Shiner, Alice, Takhar, Amrit, Jarman, Andrea, Wong, Angela, Gibbons, Anita, Lalonde, Anna, Lee, Arlene, Wilson, Ashley, Donepudi, Balaji, Coghill, Ben, de Quadros, Bruno, Bratten, Carla, Brown, Carly, Moorbey, Chantelle, Clisby, Charles, Gordon, Charles, Castle, Chris, Newark, Chris, Norris, Chrissie, A'Court, Christine, Graham, Claire, Rees, Colin, Paschalides, Costas, Morris, Danielle, Hagan, Daryl, Cronk, David, Phillips, Dean, Kejariwal, Deepak, Adams, Fran, Pesola, Francesca, Forbes, Gareth, Collins, Glenn, Irvine, Gordon, Fourie, Gysbert, Doyle, Harriet, Bowyer, Helen, Modelell, Ines, Emmerson, Ingrid, Ortiz, Jacobo, Johnson, Jenny, Ducker, Jill, Skinner, Jo, Dash, Joanne, Miralles, Jose, Ridgway, Josephine, Ince, Julia, Milne, Kate, Baseley, Laura, Lovat, Laurence, Berney, Lee, Westwood, Lisa, Leggett, Loraine, Scovell, Louise, Saunders, Lucy, Baldry, Marie, Macedo, Mario, Attah, Mark, Wallard, Matthew, Penacerrada, Melchizedek, Baker-Moffatt, Michelle, Brewer, Nick, Todd, Nicky, Zolle, Olga, Ojechi, Patrick, Banim, Paul, Spellar, Paula, Bhandari, Pradeep, Kant, Prashant, Nixon, Rachel, Russell, Rebecca, Skule, Rene, Fox, Robin, Bastiman, Sally, Warburton, Samantha, Leith-Russell, Sarah, Utting, Sarah, Wytrykowski, Sarah, Malhotra, Shalini, Woods, Sharon, Conway, Shaun, Macrae, Shona, Singh, Shruti, Fourie, Simona, Campbell, Siobhan, Goel, Sonica, Jones, Stephen, Knight, Steve, Allen, Sue, Leighton, Theresa, Bray, Tim, Santosh, Vanaja, Briggs, William, Khan, Zohrah, Sasieni, Peter

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FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models by O’Farrell, Marie, Duke, Greg, Crowley, Richard, Buckley, Douglas, Martins, Eduardo B., Bhattacharya, Dipankar, Friedman, Scott L., Kemble, George

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A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease by Fiedler, Walter, Serve, Hubert, Döhner, Hartmut, Schwittay, Michael, Ottmann, Oliver G., O'Farrell, Anne-Marie, Bello, Carlo L., Allred, Randy, Manning, William C., Cherrington, Julie M., Louie, Sharianne G., Hong, Weiru, Brega, Nicoletta M., Massimini, Giorgio, Scigalla, Paul, Berdel, Wolfgang E., Hossfeld, Dieter K.

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SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo by O'Farrell, Anne-Marie, Abrams, Tinya J., Yuen, Helene A., Ngai, Theresa J., Louie, Sharianne G., Yee, Kevin W.H., Wong, Lily M., Hong, Weiru, Lee, Leslie B., Town, Ajia, Smolich, Beverly D., Manning, William C., Murray, Lesley J., Heinrich, Michael C., Cherrington, Julie M.

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A Randomized Clinical Trial of Behavioral Couples Therapy Versus Individually Based Treatment for Women With Alcohol Dependence by Schumm, Jeremiah A., O'Farrell, Timothy J., Kahler, Christopher W., Murphy, Marie M., Muchowski, Patrice

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364 Obstetrical and neonatal outcomes among pregnancies with SARS-CoV-2 by Trahan, Marie Julie, O'Farrell, Patrick, Mitric, Cristina, Desilets, Jade, Bastrash, Marie-Pier, Malhame, Isabelle, El-Messidi, Amira, Abenhaim, Haim A.

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Partner Violence Before and After Individually Based Alcoholism Treatment for Male Alcoholic Patients by O'Farrell, Timothy J, Fals-Stewart, William, Murphy, Marie, Murphy, Christopher M

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An Innovative Phase I Clinical Study Demonstrates Inhibition of FLT3 Phosphorylation by SU11248 in Acute Myeloid Leukemia Patients by O'FARRELL, Anne-Marie, FORAN, James M, HEINRICH, Michael C, BERDEL, Wolfgang E, BELLO, Carlo, JACOBS, Mark, SCIGALLA, Paul, MANNING, William C, KELSEY, Stephen, CHERRINGTON, Julie M, FIEDLER, Walter, SERVE, Hubert, PAQUETTE, Ron L, COOPER, Maureen A, YUEN, Helene A, LOUIE, Sharianne G, KIM, Heidi, NICHOLAS, Susan

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