Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma by MA, Xiao-Hong, SHENGFU PIAO, DAN WANG, MCAFEE, Quentin W, NATHANSON, Katherine L, LUM, Julian J, LI, Lin Z, AMARAVADI, Ravi K

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Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma by Ma, Xiao-Hong, Piao, Sheng-Fu, Dey, Souvik, McAfee, Quentin, Karakousis, Giorgos, Villanueva, Jessie, Hart, Lori S, Levi, Samuel, Hu, Janice, Zhang, Gao, Lazova, Rossitza, Klump, Vincent, Pawelek, John M, Xu, Xiaowei, Xu, Wei, Schuchter, Lynn M, Davies, Michael A, Herlyn, Meenhard, Winkler, Jeffrey, Koumenis, Constantinos, Amaravadi, Ravi K

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Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency by McAfee, Quentin, Zhang, Zhihui, Samanta, Arabinda, Levi, Samuel M, Ma, Xiao-Hong, Piao, Shengfu, Lynch, John P, Uehara, Takeshi, Sepulveda, Antonia R, Davis, Lisa E, Winkler, Jeffrey D, Amaravadi, Ravi K

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Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy by Goli, Rahul, Li, Jian, Brandimarto, Jeff, Levine, Lisa D., Riis, Valerie, McAfee, Quentin, DePalma, Steven, Haghighi, Alireza, Seidman, J. G., Seidman, Christine E., Jacoby, Daniel, Macones, George, Judge, Daniel P., Rana, Sarosh, Margulies, Kenneth B., Cappola, Thomas P., Alharethi, Rami, Damp, Julie, Hsich, Eileen, Elkayam, Uri, Sheppard, Richard, Alexis, Jeffrey D., Boehmer, John, Kamiya, Chizuko, Gustafsson, Finn, Damm, Peter, Ersbøll, Anne S., Goland, Sorel, Hilfiker-Kleiner, Denise, McNamara, Dennis M., Arany, Zolt

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Abstract 112: The 3CL Protease Of SARS-CoV2 Induces Sarcomeric Degradation Through Cleavage Of The Giant Protein Obscurin by Yucel, Nora, McAfee, Quentin, Paterlini, Maria G, Arany, Zoltan

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Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force by McAfee, Quentin, Caporizzo, Matthew A, Uchida, Keita, Bedi, Kenneth C, Margulies, Kenneth B, Arany, Zolt, Prosser, Benjamin L

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PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer by Rebecca, Vito W, Nicastri, Michael C, Fennelly, Colin, Chude, Cynthia I, Barber-Rotenberg, Julie S, Ronghe, Amruta, McAfee, Quentin, McLaughlin, Noel P, Zhang, Gao, Goldman, Aaron R, Ojha, Rani, Piao, Shengfu, Noguera-Ortega, Estela, Martorella, Alessandra, Alicea, Gretchen M, Lee, Jennifer J, Schuchter, Lynn M, Xu, Xiaowei, Herlyn, Meenhard, Marmorstein, Ronen, Gimotty, Phyllis A, Speicher, David W, Winkler, Jeffrey D, Amaravadi, Ravi K

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Truncated titin proteins in dilated cardiomyopathy by McAfee, Quentin, Chen, Christina Yingxian, Yang, Yifan, Caporizzo, Matthew A, Morley, Michael, Babu, Apoorva, Jeong, Sunhye, Brandimarto, Jeffrey, Bedi, Jr, Kenneth C, Flam, Emily, Cesare, Joseph, Cappola, Thomas P, Margulies, Kenneth, Prosser, Benjamin, Arany, Zolt

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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme by Rosenfeld, Myrna R, Ye, Xiaobu, Supko, Jeffrey G, Desideri, Serena, Grossman, Stuart A, Brem, Steven, Mikkelson, Tom, Wang, Daniel, Chang, Yunyoung C, Hu, Janice, McAfee, Quentin, Fisher, Joy, Troxel, Andrea B, Piao, Shengfu, Heitjan, Daniel F, Tan, Kay-See, Pontiggia, Laura, O'Dwyer, Peter J, Davis, Lisa E, Amaravadi, Ravi K

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A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles by Rebecca, Vito W, Nicastri, Michael C, McLaughlin, Noel, Fennelly, Colin, McAfee, Quentin, Ronghe, Amruta, Nofal, Michel, Lim, Chun-Yan, Witze, Eric, Chude, Cynthia I, Zhang, Gao, Alicea, Gretchen M, Piao, Shengfu, Murugan, Sengottuvelan, Ojha, Rani, Levi, Samuel M, Wei, Zhi, Barber-Rotenberg, Julie S, Murphy, Maureen E, Mills, Gordon B, Lu, Yiling, Rabinowitz, Joshua, Marmorstein, Ronen, Liu, Qin, Liu, Shujing, Xu, Xiaowei, Herlyn, Meenhard, Zoncu, Roberto, Brady, Donita C, Speicher, David W, Winkler, Jeffrey D, Amaravadi, Ravi K

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Abstract 335: Titin Truncations in Human Heart Tissue by McAfee, Quentin, Brandimarto, Jeff, Rhoades, Joshua, Bede, Ken, Margulies, Kenneth, Arany, Zoltan

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Truncated titin protein in dilated cardiomyopathy incorporates into the sarcomere and transmits force by McAfee, Quentin, Caporizzo, Matthew A, Uchida, Keita, Bedi, Jr, Kenneth C, Margulies, Kenneth B, Arany, Zolt, Prosser, Benjamin L

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Extracellular stiffness induces contractile dysfunction in adult cardiomyocytes via cell-autonomous and microtubule-dependent mechanisms by Vite, Alexia, Caporizzo, Matthew A., Corbin, Elise A., Brandimarto, Jeffrey, McAfee, Quentin, Livingston, Carissa E., Prosser, Benjamin L., Margulies, Kenneth B.

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Truncated titin in the cardiac myofibril in dilated cardiomyopathy by McAfee, Quentin, Chen, Christina Yingxian, Yang, Yifan, Caporizzo, Matthew, Morley, Michael, Babu, Apoorva, Jeong, Sunhye, Brandimarto, Jeffrey, Bedi, Kenneth, Flam, Emily, Cesare, Joseph, Cappola, Thomas, Margulies, Kenneth, Prosser, Benjamin, Arany, Zoltan

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Truncated titin protein in dilated cardiomyopathy by McAfee, Quentin, Yingxian Chen, Christina, Yang, Yifan, Caporizzo, Matthew A., Morley, Michael P., Babu, Apoorva, Jeong, Sunhye, Brandimarto, Jeffrey, Bedi, Kenneth C., Flam, Emily, Cesare, Joseph, Cappola, Thomas P., Margulies, Kenneth B., Prosser, Benjamin L., Arany, Zolt

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Abstract P494: Truncated Titin Protein In Dilated Cardiomyopathy by McAfee, Quentin, Chen, Christina Yingxian, Caporizzo, Matthew, Morley, Michael, Babu, Apoorva, Jeong, Sunhye, Brandimarto, Jeff, Bedi, Kenneth, Flam, Emily, Cesare, Joseph, Cappola, Tom, Margulies, Kenneth B, Prosser, Benjamin, Arany, Zoltan

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ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells by Piao, Shengfu, Ojha, Rani, Rebecca, Vito W., Samanta, Arabinda, Ma, Xiao-hong, Mcafee, Quentin, Nicastri, Michael C., Buckley, Meghan, Brown, Eric, Winkler, Jeffrey D., Gimotty, Phyllis A., Amaravadi, Ravi K.

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Abstract 1024: Expression pattern of ALDH1A1 and HLTF predicts sensitivity to lysosomal autophagy inhibitors in cancer cells by Piao, Shengfu, Samanta, Arabinda, Ma, Xiaohong, Mcafee, Quentin W., Rebecca, Vito W., Buckley, Meghan, Brown, Eric J., Gimotty, Phyllis A., Amaravadi, Ravi K.

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Abstract 1018: Structural features of novel dimeric quinacrines that have single-agent antitumor activity determine the mechanism of action: destabilization of mTORC1/lysosomal int... by Rebecca, Vito W., Nicastri, Michael, McGlaughlin, Noel, McAfee, Quentin, Zhang, Gao, Alicea, Gretchen M., Piao, Shengfu, Fennelly, Colin, Murugan, Sengottuvelan, Wei, Zhi, Mills, Gordon B., Lu, Yiling, Herlyn, Meenhard, Winkler, Jeffrey D., Amaravadi, Ravi K.

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Abstract 1018: Structural features of novel dimeric quinacrines that have single-agent antitumor activity determine the mechanism of action: destabilization of mTORC1lysosomal inte... by Rebecca, Vito W, Nicastri, Michael, McGlaughlin, Noel, McAfee, Quentin, Zhang, Gao, Alicea, Gretchen M, Piao, Shengfu, Fennelly, Colin, Murugan, Sengottuvelan, Wei, Zhi, Mills, Gordon B, Lu, Yiling, Herlyn, Meenhard, Winkler, Jeffrey D, Amaravadi, Ravi K

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