Multiplex gene expression analysis for high-throughput drug discovery: screening and analysis of compounds affecting genes overexpressed in cancer cells by Johnson, Paul H, Walker, Roger P, Jones, Steven W, Stephens, Kathy, Meurer, Janet, Zajchowski, Deborah A, Luke, May M, Eeckman, Frank, Tan, Yuping, Wong, Linda, Parry, Gordon, Morgan, Jr, Thomas K, McCarrick, Meg A, Monforte, Joseph

Get full text

Multiplex Gene Expression Analysis for High-Throughput Drug Discovery: Screening and Analysis of Compounds Affecting Genes Overexpressed in Cancer Cells 1 Supplementary material fo... by Paul H. Johnson, Roger P. Walker, Steven W. Jones, Kathy Stephens, Janet Meurer, Deborah A. Zajchowski, May M. Luke, Frank Eeckman, Yuping Tan, Linda Wong, Gordon Parry, Thomas K. Morgan, Jr, Meg A. McCarrick, Joseph Monforte

Get full text

PPARδ AGONIST REN001 IMPROVES MITOCHONDRIAL FUNCTION IN SKELETAL MUSCLE: A POTENTIAL TREATMENT FOR PRIMARY MITOCHONDRIAL MYOPATHIES by Adams, John, McCarrick, Meg, O’Carroll, Colin

Get full text

Discovery of the c‑Jun N‑Terminal Kinase Inhibitor CC-90001 by Nagy, Mark A, Hilgraf, Robert, Mortensen, Deborah S, Elsner, Jan, Norris, Stephen, Tikhe, Jayashree, Yoon, Won, Paisner, David, Delgado, Mercedes, Erdman, Paul, Haelewyn, Jason, Khambatta, Godrej, Xu, Li, Romanow, William J, Condroski, Kevin, Bahmanyar, Sogole, McCarrick, Meg, Benish, Brent, Blease, Kate, LeBrun, Laurie, Moghaddam, Mehran F, Apuy, Julius, Canan, Stacie S, Bennett, Brydon L, Satoh, Yoshitaka

Get full text

Structure-based optimization of aminothiadiazole inhibitors of AKT by Mortensen, Deborah S., Hegde, Sayee G., Perrin-Ninkovic, Sophie M., Bahmanyar, Sogole, McCarrick, Meg, Harris, Roy, Hilgraf, Robert, Lee, Branden G. S., McKie, Jeff, Nadolny, Lisa, Sapienza, John, Collette, Alice, Cox, Sarah, Gamez, James C., Hensel, Jennifer L., Hua, Xuequn Helen, Leisten, Jim, Raymon, Heather K., Tran, Tam, Narla, Rama Krishna

Get full text

Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor by Plantevin Krenitsky, Véronique, Nadolny, Lisa, Delgado, Mercedes, Ayala, Leticia, Clareen, Steven S., Hilgraf, Robert, Albers, Ronald, Hegde, Sayee, D’Sidocky, Neil, Sapienza, John, Wright, Jonathan, McCarrick, Meg, Bahmanyar, Sogole, Chamberlain, Philip, Delker, Silvia L., Muir, Jeff, Giegel, David, Xu, Li, Celeridad, Maria, Lachowitzer, Jeff, Bennett, Brydon, Moghaddam, Mehran, Khatsenko, Oleg, Katz, Jason, Fan, Rachel, Bai, April, Tang, Yang, Shirley, Michael A., Benish, Brent, Bodine, Tracey, Blease, Kate, Raymon, Heather, Cathers, Brian E., Satoh, Yoshitaka

Get full text

Design, Synthesis, and Activity of a Novel Series of Factor Xa Inhibitors:  Optimization of Arylamidine Groups by Phillips, Gary, Guilford, William J, Buckman, Brad O, Davey, David D, Eagen, Keith A, Koovakkat, Sunil, Liang, Amy, McCarrick, Meg, Mohan, Raju, Ng, Howard P, Pinkerton, Michael, Subramanyam, Babu, Ho, Elena, Trinh, Lan, Whitlow, Marc, Wu, Shung, Xu, Wei, Morrissey, Michael M

Get full text

Solid-phase synthesis of naphthylamidines as factor VIIa/tissue factor inhibitors by Buckman, Brad O., Chou, Yuo-Ling, McCarrick, Meg, Liang, Amy, Lentz, Dao, Mohan, Raju, Morrissey, Michael M., Shaw, Kenneth J., Trinh, Lan, Light, David R.

Get full text