De novo assembly and delivery to mouse cells of a 101 kb functional human gene by Mitchell, Leslie A, McCulloch, Laura H, Pinglay, Sudarshan, Berger, Henri, Bosco, Nazario, Brosh, Ran, Bulajić, Milica, Huang, Emily, Hogan, Megan S, Martin, James A, Mazzoni, Esteban O, Davoli, Teresa, Maurano, Matthew T, Boeke, Jef D

Get full text

A conditional counterselectable Piga knockout in mouse embryonic stem cells for advanced genome writing applications by Zhang, Weimin, Brosh, Ran, McCulloch, Laura H., Zhu, Yinan, Ashe, Hannah, Ellis, Gwen, Camellato, Brendan R., Kim, Sang Yong, Maurano, Matthew T., Boeke, Jef D.

Get full text

Manipulating the 3D organization of the largest synthetic yeast chromosome by Zhang, Weimin, Lazar-Stefanita, Luciana, Yamashita, Hitoyoshi, Shen, Michael J, Mitchell, Leslie A, Kurasawa, Hikaru, Lobzaev, Evgenii, Fanfani, Viola, Haase, Max A B, Sun, Xiaoji, Jiang, Qingwen, Goldberg, Gregory W, Ichikawa, David M, Lauer, Stephanie L, McCulloch, Laura H, Easo, Nicole, Lin, S Jiaming, Camellato, Brendan R, Zhu, Yinan, Cai, Jitong, Xu, Zhuwei, Zhao, Yu, Sacasa, Maya, Noyes, Marcus B, Bader, Joel S, Deutsch, Samuel, Stracquadanio, Giovanni, Aizawa, Yasunori, Dai, Junbiao, Boeke, Jef D

Get full text

Context-dependent neocentromere activity in synthetic yeast chromosome VIII by Lauer, Stephanie, Luo, Jingchuan, Lazar-Stefanita, Luciana, Zhang, Weimin, McCulloch, Laura H, Fanfani, Viola, Lobzaev, Evgenii, Haase, Max A B, Easo, Nicole, Zhao, Yu, Yu, Fangzhou, Cai, Jitong, Bader, Joel S, Stracquadanio, Giovanni, Boeke, Jef D

Get full text

Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function by Luo, Jingchuan, Vale-Silva, Luis A, Raghavan, Adhithi R, Mercy, Guillaume, Heldrich, Jonna, Sun, Xiaoji, Li, Mingyu Kenneth, Zhang, Weimin, Agmon, Neta, Yang, Kun, Cai, Jitong, Stracquadanio, Giovanni, Thierry, Agnès, Zhao, Yu, Coelho, Camila, McCulloch, Laura H, Lauer, Stephanie, Kaback, David B, Bader, Joel S, Mitchell, Leslie A, Mozziconacci, Julien, Koszul, Romain, Hochwagen, Andreas, Boeke, Jef D

Get full text

Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains by McCulloch, Laura H, Sambasivam, Vijayan, Hughes, Amanda L, Annaluru, Narayana, Ramalingam, Sivaprakash, Fanfani, Viola, Lobzaev, Evgenii, Mitchell, Leslie A, Cai, Jitong, Jiang, Hua, LaCava, John, Taylor, Martin S, Bishai, William R, Stracquadanio, Giovanni, Steinmetz, Lars M, Bader, Joel S, Zhang, Weimin, Boeke, Jef D, Chandrasegaran, Srinivasan

Get full text

PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery by Ramracheya, Reshma D., McCulloch, Laura J., Clark, Anne, Wiggins, David, Johannessen, Helene, Olsen, Magnus Kringstad, Cai, Xing, Zhao, Chun-Mei, Chen, Duan, Rorsman, Patrik

Get full text

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response by Spencer, Christine N, McQuade, Jennifer L, Gopalakrishnan, Vancheswaran, McCulloch, John A, Vetizou, Marie, Cogdill, Alexandria P, Khan, Md A Wadud, Zhang, Xiaotao, White, Michael G, Peterson, Christine B, Wong, Matthew C, Morad, Golnaz, Rodgers, Theresa, Badger, Jonathan H, Helmink, Beth A, Andrews, Miles C, Rodrigues, Richard R, Morgun, Andrey, Kim, Young S, Roszik, Jason, Hoffman, Kristi L, Zheng, Jiali, Zhou, Yifan, Medik, Yusra B, Kahn, Laura M, Johnson, Sarah, Hudgens, Courtney W, Wani, Khalida, Gaudreau, Pierre-Olivier, Harris, Angela L, Jamal, Mohamed A, Baruch, Erez N, Perez-Guijarro, Eva, Day, Chi-Ping, Merlino, Glenn, Pazdrak, Barbara, Lochmann, Brooke S, Szczepaniak-Sloane, Robert A, Arora, Reetakshi, Anderson, Jaime, Zobniw, Chrystia M, Posada, Eliza, Sirmans, Elizabeth, Simon, Julie, Haydu, Lauren E, Burton, Elizabeth M, Wang, Linghua, Dang, Minghao, Clise-Dwyer, Karen, Schneider, Sarah, Chapman, Thomas, Anang, Nana-Ama A S, Duncan, Sheila, Toker, Joseph, Malke, Jared C, Glitza, Isabella C, Amaria, Rodabe N, Tawbi, Hussein A, Diab, Adi, Wong, Michael K, Patel, Sapna P, Woodman, Scott E, Davies, Michael A, Ross, Merrick I, Gershenwald, Jeffrey E, Lee, Jeffrey E, Hwu, Patrick, Jensen, Vanessa, Samuels, Yardena, Straussman, Ravid, Ajami, Nadim J, Nelson, Kelly C, Nezi, Luigi, Petrosino, Joseph F, Futreal, P Andrew, Lazar, Alexander J, Hu, Jianhua, Jenq, Robert R, Tetzlaff, Michael T, Yan, Yan, Garrett, Wendy S, Huttenhower, Curtis, Sharma, Padmanee, Watowich, Stephanie S, Allison, James P, Cohen, Lorenzo, Trinchieri, Giorgio, Daniel, Carrie R, Wargo, Jennifer A

Get full text

Association of Maternal Immune Activation during Pregnancy and Neurologic Outcomes in Offspring by Jain, Samhita, Baer, Rebecca J., McCulloch, Charles E., Rogers, Elizabeth, Rand, Larry, Jelliffe-Pawlowski, Laura, Piao, Xianhua

Get full text

A deep learning approach for fully automated cardiac shape modeling in tetralogy of Fallot by Govil, Sachin, Crabb, Brendan T., Deng, Yu, Dal Toso, Laura, Puyol-Antón, Esther, Pushparajah, Kuberan, Hegde, Sanjeet, Perry, James C., Omens, Jeffrey H., Hsiao, Albert, Young, Alistair A., McCulloch, Andrew D.

Get full text

COL6A3 Is Regulated by Leptin in Human Adipose Tissue and Reduced in Obesity by McCulloch, Laura J, Rawling, Tom J, Sjöholm, Kajsa, Franck, Niclas, Dankel, Simon N, Price, Emily J, Knight, Bridget, Liversedge, Neil H, Mellgren, Gunnar, Nystrom, Fredrik, Carlsson, Lena M, Kos, Katarina

Get full text

Global case studies for chronic kidney disease/end-stage kidney disease care by Yang, Chih-Wei, Harris, David C.H., Luyckx, Valerie A., Nangaku, Masaomi, Hou, Fan Fan, Garcia Garcia, Guillermo, Abu-Aisha, Hasan, Niang, Abdou, Sola, Laura, Bunnag, Sakarn, Eiam-Ong, Somchai, Tungsanga, Kriang, Richards, Marie, Richards, Nick, Goh, Bak Leong, Dreyer, Gavin, Evans, Rhys, Mzingajira, Henry, Twahir, Ahmed, McCulloch, Mignon I., Ahn, Curie, Osafo, Charlotte, Hsu, Hsiang-Hao, Barnieh, Lianne, Donner, Jo-Ann, Tonelli, Marcello

Get full text

Tropical root responses to global changes: A synthesis by Yaffar, Daniela, Lugli, Laynara F., Wong, Michelle Y., Norby, Richard J., Addo‐Danso, Shalom D., Arnaud, Marie, Cordeiro, Amanda L., Dietterich, Lee H., Diaz‐Toribio, Milton H., Lee, Ming Y., Ghimire, Om Prakash, Smith‐Martin, Chris M., Toro, Laura, Andersen, Kelly, McCulloch, Lindsay A., Meier, Ina C., Powers, Jennifer S., Sanchez‐Julia, Mareli, Soper, Fiona M., Cusack, Daniela F.

Get full text

A genome-wide association search for type 2 diabetes genes in African Americans by Palmer, Nicholette D, McDonough, Caitrin W, Hicks, Pamela J, Roh, Bong H, Wing, Maria R, An, S Sandy, Hester, Jessica M, Cooke, Jessica N, Bostrom, Meredith A, Rudock, Megan E, Talbert, Matthew E, Lewis, Joshua P, Ferrara, Assiamira, Lu, Lingyi, Ziegler, Julie T, Sale, Michele M, Divers, Jasmin, Shriner, Daniel, Adeyemo, Adebowale, Rotimi, Charles N, Ng, Maggie C Y, Langefeld, Carl D, Freedman, Barry I, Bowden, Donald W, Voight, Benjamin F, Scott, Laura J, Steinthorsdottir, Valgerdur, Morris, Andrew P, Dina, Christian, Welch, Ryan P, Zeggini, Eleftheria, Huth, Cornelia, Aulchenko, Yurii S, Thorleifsson, Gudmar, McCulloch, Laura J, Ferreira, Teresa, Grallert, Harald, Amin, Najaf, Wu, Guanming, Willer, Cristen J, Raychaudhuri, Soumya, McCarroll, Steve A, Langenberg, Claudia, Hofmann, Oliver M, Dupuis, Josée, Qi, Lu, Segrè, Ayellet V, van Hoek, Mandy, Navarro, Pau, Ardlie, Kristin, Balkau, Beverley, Benediktsson, Rafn, Bennett, Amanda J, Blagieva, Roza, Boerwinkle, Eric, Bonnycastle, Lori L, Boström, Kristina Bengtsson, Bravenboer, Bert, Bumpstead, Suzannah, Burtt, Noël P, Charpentier, Guillaume, Chines, Peter S, Cornelis, Marilyn, Couper, David J, Crawford, Gabe, Doney, Alex S F, Elliott, Katherine S, Elliott, Amanda L, Erdos, Michael R, Fox, Caroline S, Franklin, Christopher S, Ganser, Martha, Gieger, Christian, Grarup, Niels, Green, Todd, Griffin, Simon, Groves, Christopher J, Guiducci, Candace, Hadjadj, Samy, Hassanali, Neelam, Herder, Christian, Isomaa, Bo, Jackson, Anne U, Johnson, Paul R V, Jørgensen, Torben, Kao, Wen H L, Klopp, Norman, Kong, Augustine, Kraft, Peter, Kuusisto, Johanna, Lauritzen, Torsten, Li, Man, Lieverse, Aloysius, Lindgren, Cecilia M, Lyssenko, Valeriya, Marre, Michel, Meitinger, Thomas, Midthjell, Kristian, Morken, Mario A, Narisu, Narisu

Get full text

Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI by Vasey, Baptiste, Nagendran, Myura, Campbell, Bruce, Clifton, David A, Denaxas, Spiros, Denniston, Alastair K, Faes, Livia, Geerts, Bart, Mateen, Bilal A, McCradden, Melissa D, Morgan, Lauren, Ting, Daniel S W, Weber, Wim, Wheatstone, Peter, Lee, Aaron Y, Fraser, Alan G, Connell, Ali, Vira, Alykhan, Esteva, Andre, Beam, Andrew L, de Hond, Anne, Bradlow, Anthony, Ercole, Ari, Paez, Arsenio, Tsanas, Athanasios, Kirby, Barry, Glocker, Ben, Velardo, Carmelo, Park, Chang Min, Paton, Chris, Johner, Christian, McGenity, Clare, Faivre-Finn, Corinne, Simon, Crispin, Bzdok, Danilo, Treanor, Darren, Steiner, David F, Higgins, David, Benson, Dawn, O’Regan, Declan P, Neri, Emanuele, Magrabi, Farah, Rademakers, Frank E, Hogg, H D Jeffry, Chan, Heang-Ping, McIntyre, Hugh F, Harvey, Hugh, Habli, Ibrahim, Fackler, James C, Shaw, James, Higham, Janet, Wohlgemut, Jared M, Chong, Jaron, Cohen, Jérémie F, Kers, Jesper, Morley, Jessica, Krois, Joachim, Monteiro, Joao, Moons, Karel G M, Karpathakis, Kassandra, Catchpole, Ken, Hood, Kerenza, Balaskas, Konstantinos, Kamnitsas, Konstantinos, Militello, Laura, Oakden-Rayner, Lauren, Lovat, Laurence B, Smits, Luc J M, Hinske, Ludwig C, van Smeden, Maarten, Giavina-Bianchi, Mara, Daley, Mark, Sendak, Mark P, Sujan, Mark, Rovers, Maroeska, DeCamp, Matthew, Woodward, Matthew, Komorowski, Matthieu, Marsden, Max, Mackintosh, Maxine, Abramoff, Michael D, Armengol de la Hoz, Miguel Ángel, Hambidge, Neale, Peek, Niels, Ahmad, Omer F, Keane, Pearse A, Ferreira, Pedro N P, Mascagni, Pietro, Guan, Pujun, Chopra, Reena, Finlayson, Samuel G, Vollmer, Sebastian J, Tan, Tien-En, Stocker, Tom JW, Giannini, Valentina, Madai, Vince I, Newcombe, Virginia, Ng, Wei Yan, Park, Yoonyoung, Perkins, Zane B

Get full text

TGFβ and CIS Inhibition Overcomes NK-cell Suppression to Restore Antitumor Immunity by Souza-Fonseca-Guimaraes, Fernando, Rossi, Gustavo R., Dagley, Laura F., Foroutan, Momeneh, McCulloch, Timothy R., Yousef, Jumana, Park, Hae-Young, Gunter, Jennifer H., Beavis, Paul A., Lin, Cheng-Yu, Hediyeh-Zadeh, Soroor, Camilleri, Tania, Davis, Melissa J., Huntington, Nicholas D.

Get full text

The Lin28/let-7 Axis Regulates Glucose Metabolism by Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.

Get full text

Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease by El-Sayed, Najib M, Myler, Peter J, Bartholomeu, Daniella C, Nilsson, Daniel, Aggarwal, Gautam, Tran, Anh-Nhi, Ghedin, Elodie, Worthey, Elizabeth A, Delcher, Arthur L, Blandin, Gae̊lle, Westenberger, Scott J, Caler, Elisabet, Cerqueira, Gustavo C, Branche, Carole, Haas, Brian, Anupama, Atashi, Arner, Erik, Åslund, Lena, Attipoe, Philip, Bontempi, Esteban, Bringaud, Frédéric, Burton, Peter, Cadag, Eithon, Campbell, David A, Carrington, Mark, Crabtree, Jonathan, Darban, Hamid, da Silveira, Jose Franco, de Jong, Pieter, Edwards, Kimberly, Englund, Paul T, Fazelina, Gholam, Feldblyum, Tamara, Ferella, Marcela, Frasch, Alberto Carlos, Gull, Keith, Horn, David, Hou, Lihua, Huang, Yiting, Kindlund, Ellen, Klingbeil, Michele, Kluge, Sindy, Koo, Hean, Lacerda, Daniela, Levin, Mariano J, Lorenzi, Hernan, Louie, Tin, Machado, Carlos Renato, McCulloch, Richard, McKenna, Alan, Mizuno, Yumi, Mottram, Jeremy C, Nelson, Siri, Ochaya, Stephen, Osoegawa, Kazutoyo, Pai, Grace, Parsons, Marilyn, Pentony, Martin, Pettersson, Ulf, Pop, Mihai, Ramirez, Jose Luis, Rinta, Joel, Robertson, Laura, Salzberg, Steven L, Sanchez, Daniel O, Seyler, Amber, Sharma, Reuben, Shetty, Jyoti, Simpson, Anjana J, Sisk, Ellen, Tammi, Martti T, Tarleton, Rick, Teixeira, Santuza, Van Aken, Susan, Vogt, Christy, Ward, Pauline N, Wickstead, Bill, Wortman, Jennifer, White, Owen, Fraser, Claire M, Stuart, Kenneth D, Andersson, Björn

Get full text

Parental origin of sequence variants associated with complex diseases by Gudjonsson, Sigurjon A, Sigurdsson, Helgi, Kristinsson, Kari Th, Sigurdsson, Asgeir, Hreidarsson, Astradur B, Masson, Gisli, Ferguson-Smith, Anne C, Frigge, Michael L, Jonsson, Thorvaldur, Stacey, Simon N, Olafsson, Jon H, Benediktsdottir, Kristrun R, Gudbjartsson, Daniel F, Besenbacher, Soren, Gylfason, Arnaldur, Sigurgeirsson, Bardur, Olason, Pall I, Sverrisson, Sverrir, Stefansson, Kari, Johannsson, Oskar Th, Thorsteinsdottir, Unnur, Benediktsson, Rafn, Thorleifsson, Gudmar, Kong, Augustine, Steinthorsdottir, Valgerdur, Sulem, Patrick, Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Sigurdsson, Gunnar

Get full text

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes by Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T., Li, Q., Nie, C., Wu, R., Morris, A. P., Ladenvall, C., Cauchi, S., Stančáková, A., Andersen, G., Astrup, A., Banasik, K., Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, J. M., Kristiansen, K., Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liao, Q., Liu, X., Ma, T., Ma, X., Marre, M., Mokrosiński, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, T. W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., van’t Riet, E., van Leeuwen, N., Varga, T. V., Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., ‘t Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, T., Wang, J., Nielsen, R., Pedersen, O.

Get full text