The N-terminus of the prion protein is a toxic effector regulated by the C-terminus by Wu, Bei, McDonald, Alex J, Markham, Kathleen, Rich, Celeste B, McHugh, Kyle P, Tatzelt, Jörg, Colby, David W, Millhauser, Glenn L, Harris, David A

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A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein by McDonald, Alex J., Dibble, Jessie P., Evans, Eric G.B., Millhauser, Glenn L.

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Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR by McDonald, Alex J., Leon, Deborah R., Markham, Kathleen A., Wu, Bei, Heckendorf, Christian F., Schilling, Kevin, Showalter, Hollis D., Andrews, Philip C., McComb, Mark E., Pushie, M. Jake, Costello, Catherine E., Millhauser, Glenn L., Harris, David A.

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An inter-domain regulatory mechanism controls toxic activities of PrPC by McDonald, Alex J., Wu, Bei, Harris, David A.

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An inter-domain regulatory mechanism controls toxic activities of PrP C by McDonald, Alex J, Wu, Bei, Harris, David A

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PrP overdrive: Does inhibition of α-cleavage contribute to PrPC toxicity and prion disease? by McDonald, Alex J, Millhauser, Glenn L

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Proteolytically Resistant Cellular Prion Protein Construct Retains Metal Driven CIS-Interaction while Generating Toxicity in Cells by Roseman, Graham P., McDonald, Alex J., Wu, Bei, Harris, David A., Millhauser, Glenn L.

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PrP overdrive: Does inhibition of α-cleavage contribute to PrP C toxicity and prion disease? by McDonald, Alex J, Millhauser, Glenn L

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PrP overdrive: Does inhibition of α-cleavage contribute to PrP by McDonald, Alex J, Millhauser, Glenn L

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PrP overdrive: does inhibition of α-cleavage contribute to PrP(C) toxicity and prion disease? by McDonald, Alex J, Millhauser, Glenn L

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Altered Domain Structure of the Prion Protein Caused by Cu 2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR by McDonald, Alex J, Leon, Deborah R, Markham, Kathleen A, Wu, Bei, Heckendorf, Christian F, Schilling, Kevin, Showalter, Hollis D, Andrews, Philip C, McComb, Mark E, Pushie, M Jake, Costello, Catherine E, Millhauser, Glenn L, Harris, David A

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Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records by Thompson, Ellen J., Williams, Dylan M., Walker, Alex J., Mitchell, Ruth E., Niedzwiedz, Claire L., Yang, Tiffany C., Huggins, Charlotte F., Kwong, Alex S. F., Silverwood, Richard J., Di Gessa, Giorgio, Bowyer, Ruth C. E., Northstone, Kate, Hou, Bo, Green, Michael J., Dodgeon, Brian, Doores, Katie J., Duncan, Emma L., Williams, Frances M. K., Steptoe, Andrew, Porteous, David J., McEachan, Rosemary R. C., Tomlinson, Laurie, Goldacre, Ben, Patalay, Praveetha, Ploubidis, George B., Katikireddi, Srinivasa Vittal, Tilling, Kate, Rentsch, Christopher T., Timpson, Nicholas J., Chaturvedi, Nishi, Steves, Claire J.

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[177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial by Hofman, Michael S, Emmett, Louise, Sandhu, Shahneen, Iravani, Amir, Joshua, Anthony M, Goh, Jeffrey C, Pattison, David A, Tan, Thean Hsiang, Kirkwood, Ian D, Ng, Siobhan, Francis, Roslyn J, Gedye, Craig, Rutherford, Natalie K, Weickhardt, Andrew, Scott, Andrew M, Lee, Sze-Ting, Kwan, Edmond M, Azad, Arun A, Ramdave, Shakher, Redfern, Andrew D, Macdonald, William, Guminski, Alex, Hsiao, Edward, Chua, Wei, Lin, Peter, Zhang, Alison Y, McJannett, Margaret M, Stockler, Martin R, Violet, John A, Williams, Scott G, Martin, Andrew J, Davis, Ian D, Azad, Arun A, Chua, Wei, Davis, Ian D, Dhiantravan, Nattakorn, Emmett, Louise, Ford, Kate, Hofman, Michael S, Francis, Roslyn J, Gedye, Craig, Goh, Jeffrey C, Guminski, Alex, Hsiao, Edward, Iravani, Amir, Joshua, Anthony M, Kirkwood, Ian D, Langford, Ailsa, Lawrence, Nicola, Lee, Sze-Ting, Lin, Peter, Martin, Andrew J, McDonald, William, McJannett, Margaret M, Ng, Siobhan, Pattison, David A, Ramdave, Shakher, Rana, Nisha, Redfern, Andrew D, Rutherford, Natalie K, Sandhu, Shahneen, Scott, Andrew M, Stockler, Martin R, Subramaniam, Shalini, Tan, Thean Hsiang, Violet, John A, Weickhardt, Andrew, Williams, Scott G, Yip, Sonia, Zhang, Alison Y

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Factors associated with COVID-19-related death using OpenSAFELY by Williamson, Elizabeth J., Walker, Alex J., Bhaskaran, Krishnan, Bacon, Seb, Bates, Chris, Morton, Caroline E., Curtis, Helen J., Mehrkar, Amir, Evans, David, Inglesby, Peter, Cockburn, Jonathan, McDonald, Helen I., MacKenna, Brian, Tomlinson, Laurie, Douglas, Ian J., Rentsch, Christopher T., Mathur, Rohini, Wong, Angel Y. S., Grieve, Richard, Harrison, David, Forbes, Harriet, Schultze, Anna, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, Perera, Rafael, Evans, Stephen J. W., Smeeth, Liam, Goldacre, Ben

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Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort s... by Mathur, Rohini, Rentsch, Christopher T, Morton, Caroline E, Hulme, William J, Schultze, Anna, MacKenna, Brian, Eggo, Rosalind M, Bhaskaran, Krishnan, Wong, Angel Y S, Williamson, Elizabeth J, Forbes, Harriet, Wing, Kevin, McDonald, Helen I, Bates, Chris, Bacon, Seb, Walker, Alex J, Evans, David, Inglesby, Peter, Mehrkar, Amir, Curtis, Helen J, DeVito, Nicholas J, Croker, Richard, Drysdale, Henry, Cockburn, Jonathan, Parry, John, Hester, Frank, Harper, Sam, Douglas, Ian J, Tomlinson, Laurie, Evans, Stephen J W, Grieve, Richard, Harrison, David, Rowan, Kathy, Khunti, Kamlesh, Chaturvedi, Nishi, Smeeth, Liam, Goldacre, Ben

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Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the Open... by Bhaskaran, Krishnan, Bacon, Sebastian, Evans, Stephen JW, Bates, Chris J, Rentsch, Christopher T, MacKenna, Brian, Tomlinson, Laurie, Walker, Alex J, Schultze, Anna, Morton, Caroline E, Grint, Daniel, Mehrkar, Amir, Eggo, Rosalind M, Inglesby, Peter, Douglas, Ian J, McDonald, Helen I, Cockburn, Jonathan, Williamson, Elizabeth J, Evans, David, Curtis, Helen J, Hulme, William J, Parry, John, Hester, Frank, Harper, Sam, Spiegelhalter, David, Smeeth, Liam, Goldacre, Ben

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Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February by Grint, Daniel J, Wing, Kevin, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Evans, Stephen Jw, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Ys, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, Blomquist, Paula, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Goldacre, Ben, Smeeth, Liam, Eggo, Rosalind M

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PSMA and FDG-PET as predictive and prognostic biomarkers in patients given [177Lu]Lu-PSMA-617 versus cabazitaxel for metastatic castration-resistant prostate cancer (TheraP): a bio... by Buteau, James P, Martin, Andrew J, Emmett, Louise, Iravani, Amir, Sandhu, Shahneen, Joshua, Anthony M, Francis, Roslyn J, Zhang, Alison Y, Scott, Andrew M, Lee, Sze-Ting, Azad, Arun A, McJannett, Margaret M, Stockler, Martin R, Williams, Scott G, Davis, Ian D, Hofman, Michael S, Akhurst, Tim, Alipour, Ramin, Azad, Arun A, Banks, Patricia, Beaulieu, Alexis, Buteau, James P, Chua, Wei, Davis, Ian D, Dhiantravan, Nattakorn, Emmett, Louise, Ford, Kate, Hofman, Michael S, Francis, Roslyn J, Gedye, Craig, Goh, Jeffrey C, Guminski, Alex, Hamid, Anis, Haskali, Mohammad B, Hicks, Rodney J, Hsiao, Edward, Iravani, Amir, Joshua, Anthony M, Kirkwood, Ian D, Kong, Grace, Kwan, Edmond M, Langford, Ailsa, Lawrence, Nicola, Lee, Sze-Ting, Lewin, Jeremy, Lin, Peter, Martin, Andrew J, McDonald, William, McJannett, Margaret M, Moodie, Kate, Murphy, Declan G, Ng, Siobhan, Pattison, David A, Pokorski, Izabella, Ramdave, Shakher, Ravi Kumar, Aravind S, Redfern, Andrew D, Rutherford, Natalie K, Saghebi, Javad, Sandhu, Shahneen, Scott, Andrew M, Spain, Lavinia, Stockler, Martin R, Subramaniam, Shalini, Tan, Thean Hsiang, Thang, Sue Ping, Tran, Ben, Wallace, Roslyn, Weickhardt, Andrew, Williams, Scott G, Yip, Sonia, Zhang, Alison Y

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Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England by Grint, Daniel J, Wing, Kevin, Houlihan, Catherine, Gibbs, Hamish P, Evans, Stephen J W, Williamson, Elizabeth, McDonald, Helen I, Bhaskaran, Krishnan, Evans, David, Walker, Alex J, Hickman, George, Nightingale, Emily, Schultze, Anna, Rentsch, Christopher T, Bates, Chris, Cockburn, Jonathan, Curtis, Helen J, Morton, Caroline E, Bacon, Sebastian, Davy, Simon, Wong, Angel Y S, Mehrkar, Amir, Tomlinson, Laurie, Douglas, Ian J, Mathur, Rohini, MacKenna, Brian, Ingelsby, Peter, Croker, Richard, Parry, John, Hester, Frank, Harper, Sam, DeVito, Nicholas J, Hulme, Will, Tazare, John, Smeeth, Liam, Goldacre, Ben, Eggo, Rosalind M

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Clonality despite sex: the evolution of host-associated sexual neighborhoods in the pathogenic fungus Penicillium marneffei by Henk, Daniel A, Shahar-Golan, Revital, Devi, Khuraijam Ranjana, Boyce, Kylie J, Zhan, Nengyong, Fedorova, Natalie D, Nierman, William C, Hsueh, Po-Ren, Yuen, Kwok-Yung, Sieu, Tran P M, Kinh, Nguyen Van, Wertheim, Heiman, Baker, Stephen G, Day, Jeremy N, Vanittanakom, Nongnuch, Bignell, Elaine M, Andrianopoulos, Alex, Fisher, Matthew C

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