DCC Expression by Neurons Regulates Synaptic Plasticity in the Adult Brain by Horn, Katherine E., Glasgow, Stephen D., Gobert, Delphine, Bull, Sarah-Jane, Luk, Tamarah, Girgis, Jacklyn, Tremblay, Marie-Eve, McEachern, Danielle, Bouchard, Jean-François, Haber, Michael, Hamel, Edith, Krimpenfort, Paul, Murai, Keith K., Berns, Anton, Doucet, Guy, Chapman, C. Andrew, Ruthazer, Edward S., Kennedy, Timothy E.

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Abstract 1348: Targeted degradation of PARP14 Using a heterobifunctional small molecule by Wigle, Tim, Ren, Yue, Molina, Jennifer, Blackwell, Danielle, Schenkel, Laurie, Swinger, Kerren, Cheug, Anne, Abo, Ryan, Minissale, Elena, Lu, Alvin, Majer, Christina, Church, William, Dorsey, Bryan, Niepel, Mario, Perl, Nicholas, Kuplast-Barr, Kristy, McEachern, Kristen, Vasbinder, Melissa, Keilhack, Heike, Kuntz, Kevin

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A Diagnostic Prediction Model to Distinguish Multisystem Inflammatory Syndrome in Children by Clark, Matthew T., Rankin, Danielle A., Peetluk, Lauren S., Gotte, Alisa, Herndon, Alison, McEachern, William, Smith, Andrew, Clark, Daniel E., Hardison, Edward, Esbenshade, Adam J., Patrick, Anna, Halasa, Natasha B., Connelly, James A., Katz, Sophie E.

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Abstract 1344: Small molecule inhibitor of CD38 modulates its intra- and extracellular functions leading to antitumor activity by Shambharkar, Prashant, Blackwell, Danielle J., Vasbinder, Melissa M., Schenkel, Laurie B., Kunii, Kaiko, Lemera, Jenkins L., Kuplast-Barr, Kristy G., Ren, Yue, Bamberg, Ellen, Church, W. David, Majer, Christina R., Utley, Luke, McEachern, Kristen, Niepel, Mario, Wigle, Tim J., Kuntz, Kevin W., Richon, Victoria M., Keilhack, Heike, Gozgit, Joseph M.

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Abstract 3260: Potentiation of Type I interferon signaling leads to in vivo efficacy achieved with combination of chemotherapy and the PARP7 inhibitor RBN-2397 by Kunii, Kaiko, Song, Jeff J., Zimmerman, Danielle, Liu, Chang, Kuplast-Barr, Kristy G., Novak, Jonathan J., Nayak, Sunaina P., Gozgit, Joseph M., Vasbinder, Melissa M., McEachern, Kristen, Kuntz, Kevin W., Keilhack, Heike, Molina, Jennifer R.

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Trauma 2021: Trauma Association of Canada Annual Scientific Meeting, Vancouver, British Columbia (virtual), April 12–16, 2021Perceptions of a trauma team regarding in situ simulati... by Bednarek, Olga, O’Leary, Mike, Hurley, Sean, Cummings, Caleb, Bird, Ruth, Frattini, Sidney, McEachern, Stacey, Benjamin, Susan, Pereira, Asha, Brigode, William, MacLean, Alyssa, Moore, Lynne, Makish, Amy, Sadler, Joanne, Albacete, Samantha, Forbes, Hayley, Grzelak, Sonia, Strauss, Rachel, Upadhyaya, Yashita, Leung, Vivian, Tropiano, Joseph, Moore, Marcus, Greene, Jennifer, Goldstein, Judah, Schmitz, Erika, Bratu, Ioana, Alballa, Abdulrahman Saleh, Dawe, Philip, Malone, Judi, Javidan, Arshia P., Allen, Leah, Curtis, R. Mason, Ssebazza, Karen, Schellenberg, Morgan, Lampron, Jacinthe, Tanenbaum, Brandy, Chisholm, Allison, Ringuette, Julie, Watson, Ian, Shi, Daniel, Bhangu, Avneesh, Moffat, Brad, Fong, Deanna, Farquharson, Simon, Al Khaboori, Sadiq, Lorthios-Guilledroit, Agathe, Côté, Caroline, McPherson, John, Tran, Alexandre, Guttman, Matthew, Yeung, Matthew, Poirier, Renée-Anne, Siddiqi, Mahwash, Evans, Teresa, Guiab, Keren, Bradley, Nori, Elliott, Cara, Power, Adam, Kirkpatrick, Andrew, Merkle, Alex, Jessula, Sam, Minor, Samuel, Emsley, Jason, Sameoto, Colleen, Fitzpatrick, Eleanor, Erdogan, Mete, Green, Robert, Sibley, Aaron, Jain, Trevor, Nicholson, Brent, Stryhn, Henrik, Karsli, Cengiz, Stuhler, Rivanna, Ng, Elaine, Coates, Angela, Engels, Paul, Talsma, Akke Neel, Lobchuk, Michelle, Thongpriwan, Vipavee, Cahill, Shawn, Mis, Justin, Starr, Fredric, Bokhari, Faran, Ladak, Adil, Snelgrove, Ryan, Wang, Haili, Power, Hollie, Allen, Laura, Leeper, Rob, Parry, Neil, Ball, Ian, Vogt, Kelly, Rawls, Danielle, Ramler, Geoff, Andres, Ellie, Lakha, Nasira, Brisson, Angie, Merchant, Jennah, Widder, Sandy, Berube, Melanie

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484. Identification of Early Features to Differentiate Hospitalized Children Admitted for Suspected MIS-C from Alternative Diagnoses by Clark, Matthew T, Rankin, Danielle A, Patrick, Anna E, Gotte, Alisa, Herndon, Alison, McEachern, William, Smith, Andrew, Thompson, Mary Ann, Moore, M D, Starnes, Joseph R, Anderson, Jessica, Whitmore, Melanie, Jabs, Kathy, Kidd, Rebecca, McDaniel, Heather L, Wolf, Ryan, Clark, Daniel E, Davogustto, Giovanni, Hardison, Edward, Wells, Quinn, Parra, David, Halasa, Natasha B, Connelly, James A, Katz, Sophie E

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Abstract 2154: PARP7 inhibitor RBN-2397 increases tumoral IFN signaling leading to various tumor cell intrinsic effects and tumor regressions in mouse models by Molina, Jennifer R., Gozgit, Joseph M., Vasbinder, Melissa M., Abo, Ryan P., kunii, Kaiko, Kuplast-Barr, Kristy G., Gui, Bin, Nayak, Sunaina P., Minissale, Elena, Swinger, Kerren K., Wigle, Tim J., Lu, Alvin Z., Blackwell, Danielle J., Majer, Christina R., Ren, Yue, Bamberg, Ellen, Niepel, Mario, Mo, Jan-Rung, Church, William D., Mady, Ahmed S., Song, Jeff, Varsamis, Zacharenia A., Utley, Luke, Rao, Patricia E., Mitchison, Timoty J., Kuntz, Kevin W., Richon, Victoria M., McEachern, Kristen, Keilhack, Heike

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Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication by Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, McEachern, Ernest, Metz, Markus, Harwig, Curtis, Li, Tong-Shuang, Yang, Wen, Bogucki, David, Zhu, Yongbao, Langille, Jonathan, Veale, Duane, Ba, Tuya, Bey, Michael, Baird, Ian, Kaller, Alan, Krumpak, Maria, Leitch, David, Satori, Michael, Vocadlo, Krystyna, Guay, Danielle, Nan, Susan, Yee, Helen, Crawford, Jason, Chen, Gang, Wilson, Trevor, Carpenter, Bryon, Gauthier, David, MacFarland, Ron, Mosi, Renee, Bodart, Veronique, Wong, Rebecca, Fricker, Simon, Schols, Dominique

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