Evaluation of the Emergency Severity Index in US Emergency Departments for the Rate of Mistriage by Sax, Dana R, Warton, E Margaret, Mark, Dustin G, Vinson, David R, Kene, Mamata V, Ballard, Dustin W, Vitale, Tina J, McGaughey, Katherine R, Beardsley, Aaron, Pines, Jesse M, Reed, Mary E

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Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency by Egbertson, Melissa, McGaughey, Georgia B., Pitzenberger, Steven M., Stauffer, Shaun R., Coburn, Craig A., Stachel, Shawn J., Yang, Wenjin, Barrow, James C., Neilson, Lou Anne, McWherter, Melody, Perlow, Debra, Fahr, Bruce, Munshi, Sanjeev, Allison, Timothy J., Holloway, Katharine, Selnick, Harold G., Yang, ZhiQiang, Swestock, John, Simon, Adam J., Sankaranarayanan, Sethu, Colussi, Dennis, Tugusheva, Katherine, Lai, Ming-Tain, Pietrak, Beth, Haugabook, Shari, Jin, Lixia, Chen, I.-W., Holahan, Marie, Stranieri-Michener, Maria, Cook, Jacquelynn J., Vacca, Joseph, Graham, Samuel L.

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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pKa in enzyme inhibition by RAJAPAKSE, Hemaka A, NANTERMET, Philippe G, LAI, Ming-Tain, ESPESETH, Amy S, SHI, Xiao-Ping, COLUSSI, Dennis, PIETRAK, Beth, CROUTHAMEL, Ming-Chih, TUGUSHEVA, Katherine, QIAN HUANG, MIN XU, SIMON, Adam J, SELNICK, Harold G, KUO, Lawrence, HAZUDA, Daria J, GRAHAM, Samuel, VACCA, Joseph P, BARROW, James C, MCGAUGHEY, Georgia B, MUNSHI, Sanjeev, LINDSLEY, Stacey R, YOUNG, Mary Beth, NGO, Phung L, KATHERINE HOLLOWAY, M

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Discovery of Oxadiazoyl Tertiary Carbinamine Inhibitors of β-Secretase (BACE-1) by Rajapakse, Hemaka A, Nantermet, Philippe G, Selnick, Harold G, Munshi, Sanjeev, McGaughey, Georgia B, Lindsley, Stacey R, Young, Mary Beth, Lai, Ming-Tain, Espeseth, Amy S, Shi, Xiao-Ping, Colussi, Dennis, Pietrak, Beth, Crouthamel, Ming-Chih, Tugusheva, Katherine, Huang, Qian, Xu, Min, Simon, Adam J, Kuo, Lawrence, Hazuda, Daria J, Graham, Samuel, Vacca, Joseph P

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First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman prim... by Sankaranarayanan, Sethu, Holahan, Marie A, Colussi, Dennis, Crouthamel, Ming-Chih, Devanarayan, Viswanath, Ellis, Joan, Espeseth, Amy, Gates, Adam T, Graham, Samuel L, Gregro, Allison R, Hazuda, Daria, Hochman, Jerome H, Holloway, Katharine, Jin, Lixia, Kahana, Jason, Lai, Ming-tain, Lineberger, Janet, McGaughey, Georgia, Moore, Keith P, Nantermet, Philippe, Pietrak, Beth, Price, Eric A, Rajapakse, Hemaka, Stauffer, Shaun, Steinbeiser, Melissa A, Seabrook, Guy, Selnick, Harold G, Shi, Xiao-Ping, Stanton, Matthew G, Swestock, John, Tugusheva, Katherine, Tyler, Keala X, Vacca, Joseph P, Wong, Jacky, Wu, Guoxin, Xu, Min, Cook, Jacquelynn J, Simon, Adam J

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Discovery and X-ray Crystallographic Analysis of a Spiropiperidine Iminohydantoin Inhibitor of β-Secretase by Barrow, James C, Stauffer, Shaun R, Rittle, Kenneth E, Ngo, Phung L, Yang, ZhiQiang, Selnick, Harold G, Graham, Samuel L, Munshi, Sanjeev, McGaughey, Georgia B, Holloway, M. Katharine, Simon, Adam J, Price, Eric A, Sankaranarayanan, Sethu, Colussi, Dennis, Tugusheva, Katherine, Lai, Ming-Tain, Espeseth, Amy S, Xu, Min, Huang, Qian, Wolfe, Abigail, Pietrak, Beth, Zuck, Paul, Levorse, Dorothy A, Hazuda, Daria, Vacca, Joseph P

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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine p K a in enzyme inhibition by Rajapakse, Hemaka A., Nantermet, Philippe G., Selnick, Harold G., Barrow, James C., McGaughey, Georgia B., Munshi, Sanjeev, Lindsley, Stacey R., Young, Mary Beth, Ngo, Phung L., Katherine Holloway, M., Lai, Ming-Tain, Espeseth, Amy S., Shi, Xiao-Ping, Colussi, Dennis, Pietrak, Beth, Crouthamel, Ming-Chih, Tugusheva, Katherine, Huang, Qian, Xu, Min, Simon, Adam J., Kuo, Lawrence, Hazuda, Daria J., Graham, Samuel, Vacca, Joseph P.

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SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pK sub(a) in enzyme inhibition by Rajapakse, Hemaka A, Nantermet, Philippe G, Selnick, Harold G, Barrow, James C, McGaughey, Georgia B, Munshi, Sanjeev, Lindsley, Stacey R, Young, Mary Beth, Ngo, Phung L, Holloway, MKatherine, Lai, Ming-Tain, Espeseth, Amy S, Shi, Xiao-Ping, Colussi, Dennis, Pietrak, Beth, Crouthamel, Ming-Chih, Tugusheva, Katherine, Huang, Qian, Xu, Min, Simon, Adam J, Kuo, Lawrence, Hazuda, Daria J, Graham, Samuel, Vacca, Joseph P

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First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates... by Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi, Ming-Chih Crouthamel, Viswanath Devanarayan, Joan Ellis, Amy Espeseth, Adam T. Gates, Samuel L. Graham, Allison R. Gregro, Daria Hazuda, Jerome H. Hochman, Katharine Holloway, Lixia Jin, Jason Kahana, Ming-tain Lai, Janet Lineberger, Georgia McGaughey, Keith P. Moore, Philippe Nantermet, Beth Pietrak, Eric A. Price, Hemaka Rajapakse, Shaun Stauffer, Melissa A. Steinbeiser, Guy Seabrook, Harold G. Selnick, Xiao-Ping Shi, Matthew G. Stanton, John Swestock, Katherine Tugusheva, Keala X. Tyler, Joseph P. Vacca, Jacky Wong, Guoxin Wu, Min Xu, Jacquelynn J. Cook, Adam J. Simon

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